Production of anti-insulin monoclonal antibody and its clinical application

Diabetes Research and Clinical Practice

Volumn 7, Issue SUPPL. 1, 1989, Pages

  Ishihara, Kenzo ^a   Taniguchi, Hiroshi ^a   Hara, Yasuhisa ^a   Ejiri, Kazushige ^a   Baba, Shigeaki ^a   Shiroza, Satoshi ^b  

^a KOBE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b SEKISUI CHEMICAL CO LTD   (Japan)

Author keywords

Anti insulin monoclonal antibody; Clinical application; Production

Indexed keywords

GLUCAGON; MONOCLONAL ANTIBODY; RADIOISOTOPE; SOMATOSTATIN;

ANIMAL CELL; ANIMAL EXPERIMENT; CELL CULTURE; CONTROLLED STUDY; ENZYME IMMUNOASSAY; MOUSE; NONHUMAN; PRIORITY JOURNAL; RADIOIMMUNOASSAY;

ANIMAL; ANTIBODIES, MONOCLONAL; HUMAN; HYBRIDOMAS; IMMUNOENZYME TECHNIQUES; INSULIN; MALE; MICE; MICE, INBRED BALB C; RADIOIMMUNOASSAY; SWINE;

EID: 0024396751     PISSN: 01688227     EISSN: None     Source Type: Journal    
DOI: 10.1016/0168-8227(89)90091-0     Document Type: Article

References (9)

1. Continuous cultures of fused cells secreting antibody of predefined specificity
2. Use of polyethylene glycol to separate free and antibody-bound peptide hormones in radioimmunoassay
3. Overview: monoclonal antibodies
4. Application of monoclonal antibody techniques to endocrinology
5. Hybridoma antibody recognition of the insulin molecule
6. Mapping epitopes on the insulin molecule using monoclonal antibodies
7. Idiotypes on monoclonal antibodies to bovine insulin 1. Two public idiotypes on antibovine insulin hybridomas define idiotypically distinct families of hybridomas
8. Binding of insulin to its receptor impairs recognition by monoclonal anti-insulin antibodies