Pyroglutamyl peptidase II, a thyrotropin releasing hormone degrading enzyme: purification and specificity studies of the rabbit brain enzyme

Neurochemistry International

Volumn 15, Issue 1, 1989, Pages 81-89

  Wilk, Sherwin ^a   Wilk, Elizabeth K ^a  

^a CITY UNIVERSITY OF NEW YORK   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PEPTIDASE; PROTIRELIN;

ANIMAL CELL; BRAIN HOMOGENATE; ENZYME PURIFICATION; NONHUMAN; PRIORITY JOURNAL;

EID: 0024389791     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/0197-0186(89)90079-X     Document Type: Article

References (33)

1. Estimation of molecular weight of proteins by Sephadex-gel filtration
2. Adenohypophyseal degradation of thyrotropin releasing hormone regulated by thyroid hormones
3. Characterization of a thyroliberin-degrading serum enzyme catalyzing the hydrolysis of thyroliberin at the pyroglutamyl-histidine bond
4. Specificity of a serum peptidase hydrolyzing thyroliberin at the pyroglutamyl-histidine bond
5. A new coupling component for sulfanilamide determination
6. An evaluation of the role of a pyroglutamyl peptidase, a post-proline cleaving enzyme and a post-proline dipeptidyl amino peptidase, each purified from the soluble fraction of guinea-pig brain, in the degradation of thyroliberin in vitro
7. Physiological relevance of pyroglutamate aminopeptidase II
8. Purification and characterization of a novel neurotensin-degrading peptidase from rat brain synaptic membranes
9. Disc electrophoresis—II. Method and application to human serum proteins
10. The determination of enzyme inhibitor constants
11. The direct linear plot. A new graphical procedure for estimating enzyme kinetic parameters
12. Delineation of a particulate thyrotropin-releasing hormone-degrading enzyme in rat brain by the use of specific inhibitors of prolyl endopeptidase and pyroglutamyl peptide hydrolase
13. Presence of a membrane bound pyroglutamyl aminopeptidase degrading thyrotropin releasing hormone in rat brain
14. The colorimetric determination of leucine aminopeptidase in urine and serum of normal subjects and patients with cancer and other diseases
15. Localization of thyroliberin pyroglutamyl peptidase on synaptosomal-membrane preparations of guinea-pig brain tissue
16. Enzymic inactivation of hypothalamic regulatory hormones
17. Reactivity of cyclic peptides. III. Reaction of isomeric histidine, tyrosine peptides with p-nitrophenyl acetate
18. N-Carbobenzoxy-L-pyroglutamyl-L-histidyl peptides
19. The use of analogues of TRH to probe the specificity of pyroglutamyl peptidase II
20. Protein measurement with the Folin phenol reagent
21. Bovine pituitary pyrrolidonecarboxylyl peptidase
22. Purification and kinetic studies on a narrow specificity synaptosomal membrane pyroglutamate aminopeptidase from guinea-pig brain
23. Regulation of thyrotropin releasing hormone degrading enzymes in rat brain and pituitary by L-3,5,3′-triiodothyronine
24. Characterization of a pyroglutamate aminopeptidase from rat serum that degrades thyrotropin releasing hormone
25. Subcellular distribution of the enzymes degrading thyrotropin releasing hormone and metabolites in rat brain
26. Are there neuropeptide-specific peptidases?
27. Prolyl endopeptidase
28. Neuropeptide-specific peptidases: Does brain contain a specific TRH-degrading enzyme?
29. Inhibition of rabbit brain prolyl endopeptidase by N-benzyloxycarbonyl-prolyl-prolinal, a transition state aldehyde inhibitor
30. Pyroglutamyl diazomethyl ketone: Potent inhibitor of pyroglutamyl peptide hydrolase
31. Purification and properties of rabbit brain “Thyroliberinase”, a membrane-bound thyrotropin-releasing hormone degrading enzyme
32. Post-proline dipeptidyl aminopeptidase (dipeptidyl aminopeptidase IV) from lamb kidney. Purification and some enzymatic properties