SCOPUS 정보 검색 플랫폼

Angewandte Chemie International Edition in English

Volumn 28, Issue 7, 1989, Pages 870-878

The Purine Path to Chemotherapy (Nobel Lecture)

(1) Elion, Gertrude B a

a Burroughs Wellcome Co (United States)

Author keywords

Drug research; Nobel lecture; Purine path

Indexed keywords

ACICLOVIR; ADENOSINE DERIVATIVE; ALLOPURINOL; ALLOPURINOL RIBOSIDE; AZATHIOPRINE; MERCAPTOPURINE; PURINE DERIVATIVE; TIOGUANINE; VIDARABINE; XANTHINE OXIDASE;

CANCER; DRUG METABOLISM; DRUG RESEARCH; GOUT; IMMUNOSUPPRESSIVE TREATMENT; REVIEW; STRUCTURE ACTIVITY RELATION;

EID: 0024375599 PISSN: 05700833 EISSN: 15213773 Source Type: Journal
DOI: 10.1002/anie.198908701 Document Type: Review

Times cited : (36)

References (160)

1
- 0002009389
- (1940) Br. J. Exp. Pathol. , vol.21 , pp. 74
- Woods, D.D.¹

2
- 84990129333
- Lancet , vol.1940 , pp. 955
- Fildes, P.¹

3
- 0342271384
- (1950) J. Biol. Chem. , vol.183 , pp. 1
- Hitchings, G.H.¹ Elion, G.B.² Falco, E.A.³ Russell, P.B.⁴ Sherwood, M.B.⁵ VanderWerff, H.⁶

4
- 0010229670
- (1950) Ann. N. Y. Acad. Sci. , vol.52 , pp. 1318
- Hitchings, G.H.¹ Elion, G.B.² Falco, E.A.³ Russell, P.B.⁴ VanderWerff, H.⁵

5
- 0000327611
- (1947) J. Biol. Chem. , vol.167 , pp. 461
- Kalckar, H.M.¹

6
- 84894891273
- The Identification of Guanine in Extracts of Girella Nigricans: The Specificity of Guanase
- (1944) Proceedings of the National Academy of Sciences , vol.30 , pp. 294
- Hitchings, G.H.¹ Falco, E.A.²

7
- 84965948636
- (1950) Fed. Proc. Fed. Am. Soc. Exp. Biol. , vol.9 , pp. 197
- Lorz, D.C.¹ Hitchings, G.H.²

8
- 37049193425
- The Structure and Synthesis of the Liver L. casei Factor
- (1946) Science , vol.103 , pp. 667
- Angier, R.B.¹ Boothe, J.H.² Hutchings, B.L.³ Mowat, J.H.⁴ Semb, J.⁵ Stokstad, E.L.R.⁶ Subbarow, Y.⁷ Waller, C.W.⁸ Cosulich, D.B.⁹ Fahrenbach, M.J.¹⁰ Hultquist, M.E.¹¹ Kuh, E.¹² Northey, E.H.¹³ Seeger, D.R.¹⁴ Stickels, J.P.¹⁵ Smith, J.M.¹⁶

9
- 37049212222
- (1945) Science (Washington) , vol.102 , pp. 251
- Hitchings, G.H.¹ Falco, E.A.² Sherwood, M.B.³

10
- 60749122636
- (1950) J. Biol. Chem. , vol.185 , pp. 651
- Elion, G.B.¹ Hitchings, G.H.²

11
- 0005739849
- Pyrimidine derivatives as antagonists of pteroylglutamic acid.
- (1948) J Biol Chem , vol.174 , pp. 765
- Hitchings, G.H.¹ Elion, G.B.² VanderWerff, H.³ Falco, E.A.⁴

12
- 84936314106
- The limitations of inhibition analysis.
- (1948) J Biol Chem , vol.174 , pp. 1037
- Hitchings, G.H.¹ Elion, G.B.² VanderWerff, H.³

13
- 84990089209
- J. Chem. Soc. , vol.1944 , pp. 124
- Carrington, H.C.¹

14
- 0000345568
- (1952) J. Am. Chem. Soc. , vol.74 , pp. 411
- Elion, G.B.¹ Burgi, E.² Hitchings, G.H.³

15
- 33947464420
- (1955) J. Am. Chem. Soc. , vol.77 , pp. 1676
- Elion, G.B.¹ Hitchings, G.H.²

16
- 33645407998
- (1950) J. Biol. Chem. , vol.187 , pp. 511
- Elion, G.B.¹ Hitchings, G.H.²

17
- 77049151825
- (1953) J. Biol. Chem. , vol.200 , pp. 7
- Elion, G.B.¹ VanderWerff, H.² Hitchings, G.H.³ Basis, M.E.⁴ Levin, D.H.⁵ Brown, J.B.⁶

18
- 0001592508
- (1955) J. Biol. Chem. , vol.215 , pp. 417
- Kornberg, A.¹ Lieberman, I.² Simms, E.S.³

19
- 1842394042
- (1949) Cancer (Philadelphia) , vol.2 , pp. 119
- Burchenal, J.H.¹ Bendich, A.² Brown, J.B.³ Elion, G.B.⁴ Hitchings, G.H.⁵ Rhoads, C.P.⁶ Stock, C.C.⁷

20
- 76549239062
- (1951) Cancer (Philadelphia) , vol.4 , pp. 186
- Biesele, J.J.¹ Berger, R.E.² Wilson, A.Y.³ Hitchings, G.H.⁴ Elion, G.B.⁵

21
- 0011368517
- (1951) Cancer (Philadelphia) , vol.4 , pp. 549
- Burchenal, J.H.¹ Karnofsky, D.A.² Kingsley‐Pillars, E.M.³ Southam, C.M.⁴ Myers, W.P.L.⁵ Escher, G.C.⁶ Craver, L.F.⁷ Dargeon, W.⁸ Rhoads, C.P.⁹

22
- 24344480503
- (1949) Science (Washington) , vol.110 , pp. 454
- Thompson, R.L.¹ Wilkin, M.L.² Hitchings, G.H.³ Elion, G.B.⁴ Falco, E.A.⁵ Russell, P.B.⁶

23
- 2342555005
- (1950) J. Immunol. , vol.65 , pp. 529
- Thompson, R.L.¹ Price, M.L.² Menton, S.A.³ Elion, G.B.⁴ Hitchings, G.H.⁵

24
- 0000204463
- (1951) J. Biol. Chem. , vol.192 , pp. 505
- Elion, G.B.¹ Hitchings, G.H.² VanderWerff, H.³

25
- 0344842419
- 6-Mercaptopurine: effects in mouse sarcoma 180 and in normal animals.
- (1953) Cancer Res , vol.13 , pp. 593
- Clarke, D.A.¹ Phillips, F.S.² Sternberg, S.S.³ Stock, C.C.⁴ Elion, G.B.⁵ Hitchings, G.H.⁶

26
- 0003170385
- (1954) Ann. N. Y. Acad. Sci. , vol.60 , pp. 283
- Philips, F.S.¹ Sternberg, S.S.² Hamilton, L.³ Clarke, D.A.⁴

27
- 0000284526
- (1953) Blood , vol.8 , pp. 965
- Burchenal, J.H.¹ Murphy, M.L.² Ellison, R.R.³ Sykes, M.P.⁴ Tan, C.T.C.⁵ Leone, L.A.⁶ Karnofsky, D.A.⁷ Craver, L.F.⁸ Dargeon, H.W.⁹ Rhoads, C.P.¹⁰

28
- 84990137378
- C. P. Rhoads, Ann. N. Y. Acad. Sci.
- (1954) 6‐Mereaptopurine , vol.60 , pp. 183

29
- 84910180690
- (1954) Ann. N. Y. Acad. Sci. , vol.60 , pp. 200
- Elion, G.B.¹ Singer, S.² Hitchings, G.H.³

30
- 33645268977
- (1953) J. Biol. Chem. , vol.204 , pp. 35
- Elion, G.B.¹ Singer, S.² Hitchings, G.H.³

31
- 49749180640
- (1957) Arch. Biochem. Biophys. , vol.71 , pp. 358
- Balis, M.E.¹ Levin, D.H.² Brown, G.B.³ Elion, G.B.⁴ Nathan, H.C.⁵ Hitchings, G.H.⁶

32
- 84918013437
- G. E. W. Wolstenholme, C. M. O'Connor, Churchill, London
- (1957) The Chemistry and Biology of Purines

33
- 84990100860
- in [31 a] pp. 204–232.
- Greenberg, G.R.¹ Jaenicke, L.²

34
- 84990155694
- in [31 a], pp. 233–252.
- Buchanan, J.M.¹ Flaks, J.G.² Hartman, S.C.³ Levenberg, B.⁴ Lukens, L.N.⁵ Warren, L.⁶

35
- 0001169833
- (1959) Adv. Enzymol. Relat. Subj. Biochem. , vol.21 , pp. 199
- Buchanan, J.M.¹ Hartman, S.C.²

36
- 84936302570
- I. Brodsky, S. B. Kahn, J. H. Moyer, Grune & Stratton, New York
- (1972) Cancer Chemotherapy II, Twenty‐Second Hahnemann Symposium , pp. 23-32
- Hitchings, G.H.¹ Elion, G.B.²

37
- 84914423887
- Williams & Wilkins, Baltimore
- (1975) Pharmacological Basis of Cancer Chemotherapy , pp. 547-564
- Elion, G.B.¹

38
- 0006608479
- (1954) Ann. N. Y. Acad. Sci. , vol.60 , pp. 297
- Elion, G.B.¹ Bieber, S.² Hitchings, G.H.³

39
- 0344099828
- (1954) Ann. N. Y. Acad. Sci. , vol.60 , pp. 304
- Hamilton, L.¹ Elion, G.B.²

40
- 84936329134
- (1957) Proc. R. Soc. Med. , vol.50 , pp. 7
- Elion, G.B.¹

41
- 0000082652
- (1958) Cancer Res. , vol.18 , pp. 445
- Clarke, D.A.¹ Elion, G.B.² Hitchings, G.H.³ Stock, C.C.⁴

42
- 0141899196
- (1959) J. Am. Chem. Soc. , vol.81 , pp. 1898
- Elion, G.B.¹ Goodman, I.² Lange, W.³ Hitchings, G.H.⁴

43
- 0037797348
- (1960) Cancer Chemother. Rep. , vol.8 , pp. 36
- Elion, G.B.¹ Bieber, S.² Hitchings, G.H.³

44
- 0037797350
- (1960) Cancer Chemother. Rep. , vol.8 , pp. 47
- Elion, G.B.¹ Callahan, S.W.² Hitchings, G.H.³ Rundles, R.W.⁴

45
- 84990135667
- (1962) Proc. Int. Congr. Hematol. 8th , vol.1960 , pp. 642-645
- Elion, G.B.¹ Callahan, S.W.² Hitchings, G.H.³ Rundles, R.W.⁴

46
- 33947470277
- (1959) J. Am. Chem. Soc. , vol.81 , pp. 3042
- Elion, G.B.¹ Mueller, S.² Hitchings, G.H.³

47
- 0038959862
- (1963) Cancer Res. , vol.23 , pp. 1207
- Elion, G.B.¹ Callahan, S.² Rundles, R.W.³ Hitchings, G.H.⁴

48
- 0014087635
- (1967) Fed. Proc. Fed. Am. Soc. Exp. Biol. , vol.26 , pp. 898
- Elion, G.B.¹

49
- 0015713214
- (1973) J. Pharmacol. Exp. Ther. , vol.187 , pp. 588
- de Miranda, P.¹ Beacham, L.M.² Creagh, T.H.³ Elion, G.B.⁴

50
- 0003302198
- (1975) Handb. Exp. Pharmacol. , vol.38 , pp. 404-425
- Elion, G.B.¹ Hitchings, G.H.²

51
- 0016589408
- (1975) J. Pharmacol. Exp. Ther. , vol.195 , pp. 50
- de Miranda, P.¹ Beacham, L.M.² Creagh, T.H.³ Elion, G.B.⁴

52
- 0002539411
- (1961) Cancer Chemother. Rep. , vol.14 , pp. 93
- Elion, G.B.¹ Callahan, S.² Bieber, S.³ Rundles, R.W.⁴

53
- 33746929768
- (1961) Cancer Chemother. Rep. , vol.14 , pp. 99
- Rundles, R.W.¹ Laszlo, J.² Itoga, T.³ Hobson, G.B.⁴ Garrison, F.E.⁵

54
- 84964117731
- Effect of 6-Mercaptopurine on Antibody Production.
- (1958) Experimental Biology and Medicine , vol.99 , pp. 164
- Schwartz, R.¹ Stack, J.² Dameshek, W.³

55
- 0013952824
- (1966) J. Exp. Med. , vol.124 , pp. 363
- Chanmougan, D.¹ Schwartz, R.S.²

56
- 36949079215
- (1959) Nature (London) , vol.183 , pp. 1682
- Schwartz, R.¹ Dameshek, W.²

57
- 25844508400
- (1961) Proc. Soc. Exp. Biol. Med. , vol.107 , pp. 796
- Nathan, H.C.¹ Bieber, S.² Elion, G.B.³ Hitchings, G.H.⁴

58
- 73649168363
- (1962) Proc. Soc. Exp. Biol. Med. , vol.111 , pp. 334
- Bieber, S.¹ Elion, G.B.² Hitchings, G.H.³ Hooper, D.C.⁴ Nathan, H.C.⁵

59
- 84990100969
- Lancet , vol.1960 , pp. 417
- Calne, R.Y.¹

60
- 0345615911
- (1961) Transplant. Bull. , vol.28 , pp. 65
- Calne, R.Y.¹

61
- 0000418858
- (1962) Ann. N. Y. Acad. Sci. , vol.99 , pp. 743
- Calne, R.Y.¹ Alexandra, G.P.J.² Murray, J.E.³

62
- 73649153279
- (1963) N. Engl. J. Med. , vol.268 , pp. 1315
- Murray, J.E.¹ Merrill, J.P.² Harrison, J.H.³ Wilson, R.E.⁴ Dammin, G.J.⁵

63
- 84990137817
- Advisory Committee to the Renal Transplant Registry
- (1975) The Twelfth Report of the Human Renal Transplant Registry (JAMA J. Am. Med. Assoc. , vol.233 , pp. 787

64
- 0021052020
- (1983) Transplantation , vol.36 , pp. 658
- Perdue, S.T.¹ Terasaki, P.I.² Cats, S.³ Mickey, M.R.⁴

65
- 0023872053
- (1988) Transplantation , vol.45 , pp. 410
- Takiff, H.¹ Cook, D.J.² Himaya, N.S.³ Mickey, M.R.⁴ Terasaki, P.I.⁵

66
- 0344353552
- (1963) Pharmacol. Rev. , vol.15 , pp. 365
- Hitchings, G.H.¹ Elion, G.B.²

67
- 0342505924
- Antipurines and Purine Metabolism
- (1988) Handb. Exp. Pharmacol. , vol.85 , pp. 517-533
- Wolberg, G.¹

68
- 0016770050
- (1975) Arthritis Rheum. , vol.18 , pp. 15
- Hunter, T.¹ Urowitz, M.B.² Gordon, D.A.³ Smythe, H.A.⁴ Ogryzlo, M.A.⁵

69
- 0009637250
- (1962) Cancer Chemother. Rep. , vol.16 , pp. 197
- Elion, G.B.¹ Callahan, S.W.² Hitchings, G.H.³ Rundles, R.W.⁴ Laszlo, J.⁵

70
- 0002294206
- (1963) Biochem. Pharmacol. , vol.12 , pp. 85
- Elion, G.B.¹ Callahan, S.² Nathan, H.³ Bieber, S.⁴ Rundles, R.W.⁵ Hitchings, G.H.⁶

71
- 0000249506
- (1963) Trans. Assoc. Am. Physicians , vol.76 , pp. 126
- Rundles, R.W.¹ Wyngaarden, J.B.² Hitchings, G.H.³ Elion, G.B.⁴ Silberman, H.R.⁵

72
- 0013970076
- (1966) Ann. Rheum. Dis. , vol.25 , pp. 615
- Rundles, R.W.¹

73
- 0021816364
- (1985) Cancer Res. , vol.45 , pp. 2415
- Hitchings, G.H.¹ Elion, G.B.²

74
- 34247511889
- (1966) Am. J. Med. , vol.40 , pp. 548
- Vogler, W.R.¹ Bain, J.A.² Huguley, C.M.³ Palmer, H.G.⁴ Lowrey, M.E.⁵

75
- 0013965754
- (1966) Ann. Rheum. Dis. , vol.25 , pp. 601
- Hitchings, G.H.¹

76
- 84990076092
- J. T. Scott, Ann. Rheum. Dis.
- (1966) Symposium on Allopurinol , vol.25 , pp. 599

77
- 0013966678
- (1966) Ann. Rheum. Dis. , vol.25 , pp. 608
- Elion, G.B.¹

78
- 0014939684
- (1970) J. Biol. Chem. , vol.245 , pp. 2837
- Massey, V.¹ Komai, H.² Palmer, G.³ Elion, G.B.⁴

79
- 78650521802
- (1970) Vitam. Horm. (N. Y.) , vol.28 , pp. 505
- Massey, V.¹ Komai, H.² Palmer, G.³ Elion, G.B.⁴

80
- 0013926855
- (1966) Biochem. Pharmacol. , vol.15 , pp. 863
- Elion, G.B.¹ Kovensky, A.² Hitchings, G.H.³ Metz, E.⁴ Rundles, R.W.⁵

81
- 0001446652
- Allopurinol and Other Inhibitors of Urate Synthesis
- (1978) Handb. Exp. Pharmacol. , vol.51 , pp. 485-514
- Elion, G.B.¹

82
- 0014312197
- (1968) Am. J. Med. , vol.45 , pp. 69
- Elion, G.B.¹ Yü² Gutman, A.B.³ Hitchings, G.H.⁴

83
- 0001010840
- (1964) Am. J. Med. , vol.37 , pp. 885
- Yü¹ Gutman, A.B.²

84
- 0008682760
- (1963) Biochim. Biophys. Acta , vol.72 , pp. 119
- Pomales, R.¹ Bieber, S.² Friedman, R.³ Hitchings, G.H.⁴

85
- 4243343414
- (1965) Biochim. Biophys. Acta , vol.95 , pp. 505
- Pomales, R.¹ Elion, G.B.² Hitchings, G.H.³

86
- 0343417165
- The regulation of activity of phosphoribosyl-pyrophosphate amidotransferase by purine ribonacleotides: a potential feedback control of purine biosyntoesis.
- (1959) J Biol Chem , vol.234 , pp. 1492
- Wyngaarden, J.B.¹ Ashton, D.M.²

87
- 0001315431
- (1965) J. Clin. Invest. , vol.44 , pp. 623
- Goldfinger, S.¹ Klinenberg, J.R.² Seegmiller, J.E.³

88
- 84873780964
- (1965) Ann. Intern. Med. , vol.62 , pp. 639
- Klinenberg, J.R.¹ Goldfinger, S.E.² Seegmiller, J.E.³

89
- 0021808688
- (1985) Arch Intern. Med. , vol.145 , pp. 1492
- Rundles, R.W.¹

90
- 84990159457
- A. Rapado, R. W. E. Watts, C. H. M. M. DeBruyn, Purine Metabolism in Man III, Plenum, New York
- (1980)

91
- 84990137885
- in [88a] Part A, pp. 263–267.
- Elion, G.B.¹ Benezra, F.M.² Beardmore, T.D.³ Keller, W.N.⁴

92
- 0013878277
- (1966) Ann. Intern. Med. , vol.64 , pp. 229
- Rundles, R.W.¹ Metz, E.² Silberman, H.R.³

93
- 0013966249
- (1966) Ann. Rheum. Dis. , vol.25 , pp. 691
- de Vries, A.¹ Frank, M.² Liberman, U.A.³ Sperling, O.⁴

94
- 84989996668
- Xanthine oxidase inhibition in the management of hyperuricemia in leukemias and lymphomas
- (1965) Arthritis & Rheumatism , vol.8 , pp. 896
- Krakoff, I.H.¹

95
- 0016056036
- Antileishmanial Effect of Allopurinol
- (1974) Antimicrobial Agents and Chemotherapy , vol.5 , pp. 469
- Pfaller, M.A.¹ Marr, J.J.²

96
- 0018764380
- (1979) J. Biol. Chem. , vol.254 , pp. 3959
- Nelson, D.J.¹ Bugge, C.J.I.² Elion, G.B.³ Berens, R.L.⁴ Mary, J.J.⁵

97
- 0018598669
- (1979) J. Biol. Chem. , vol.254 , pp. 11 544
- Nelson, D.J.¹ LaFon, S.W.² Tuttle, J.V.³ Miller, W.H.⁴ Miller, R.L.⁵ Krenitsky, T.A.⁶ Elion, G.B.⁷ Berens, R.L.⁸ Mary, J.J.⁹

98
- 0018135606
- (1978) Science (Washington) , vol.201 , pp. 1018
- Marr, J.¹ Berens, R.² Nelson, D.³

99
- 0018718810
- (1979) J. Biol. Chem. , vol.254 , pp. 8422
- Spector, T.¹ Jones, T.E.² Elion, G.B.³

100
- 84990137934
- in [88a] Part B, pp. 271–276.
- Krenitsky, T.A.¹ Koszalka, G.W.² Tuttle, J.V.³ Adamczyk, D.L.⁴ Elion, G.B.⁵ Mary, J.J.⁶

101
- 0018889614
- (1980) Biochem. Pharmacol. , vol.29 , pp. 2397
- Berens, R.L.¹ Mary, J.J.² Nelson, D.J.³ LaFon, S.W.⁴

102
- 0020079254
- (1982) Biochem. Pharmacol. , vol.31 , pp. 231
- LaFon, S.W.¹ Nelson, D.J.² Berens, R.L.³ Marr, J.J.⁴

103
- 0020449998
- (1982) Antimicrob. Agents Chemother. , vol.22 , pp. 657
- Berens, R.L.¹ Marr, J.J.² Steele De Cruz, F.³ Nelson, D.J.⁴

104
- 0020061061
- (1982) Biochem. Pharmacol. , vol.31 , pp. 225
- Spector, T.¹ Berens, R.L.² Mary, J.J.³

105
- 0016592841
- (1975) Biochem. Pharmacol. , vol.24 , pp. 1235
- Nelson, D.J.¹ Elion, G.B.²

106
- 0019456643
- (1981) Trans. R. Soc. Trop. Med. Hyg. , vol.75 , pp. 556
- Kager, P.A.¹ Rees, P.H.² Wellde, B.T.³ Hockmeyer, W.T.⁴ Lyerly, W.H.⁵

107
- 0022407820
- (1985) Arq. Bras. Cardiol. , vol.45 , pp. 217
- Meirovich, C.I.¹ Montrull, H.L.² Gallerano, R.H.³ Sosa, R.R.⁴

108
- 0014389530
- (1968) Chemotherapy (Basel) , vol.13 , pp. 321
- Schabel, F.M.¹

109
- 0016590235
- (1975) Ann. N. Y. Acad. Sci. , vol.255 , pp. 468
- Elion, G.B.¹ Rideout, J.L.² de Miranda, P.³ Collins, P.⁴ Bauer, D.J.⁵

110
- 0015044567
- (1971) J. Med. Chem. , vol.14 , pp. 367
- Schaeffer, H.J.¹ Gurwara, S.² Vince, R.³ Bittner, S.⁴

111
- 0017639148
- (1977) Proc. Natl. Acad. Sci. USA , vol.74 , pp. 5716
- Elion, G.B.¹ Furman, P.A.² Fyfe, J.A.³ de Miranda, P.⁴ Beauchamp, L.⁵ Schaeffer, H.J.⁶

112
- 0017811137
- (1978) Nature (London) , vol.272 , pp. 583
- Schaeffer, H.J.¹ Beauchamp, L.² de Miranda, P.³ Elion, G.B.⁴ Bauer, D.J.⁵ Collins, P.⁶

113
- 84912428241
- (1982) Fed. Proc. Fed. Am. Soc. Exp. Biol. , vol.41 , pp. 1733
- Good, S.S.¹ de Miranda, P.²

114
- 0011869515
- (1983) Clin. Pharmacol. Ther. (St. Louis) , vol.33 , pp. 256
- Krasny, H.C.¹ Liao, S.H.T.² Good, S.S.³ Petty, B.⁴ Lietman, P.S.⁵

115
- 0020617884
- (1983) Biochem. Pharmacol. , vol.32 , pp. 2505
- Spector, T.¹ Jones, T.E.² Beacham, L.M.³

116
- 0019906763
- (1982) Am. J. Med. , vol.73 , pp. 7
- Elion, G.B.¹

117
- 0021020843
- (1983) J. Antimicrob. Chemother. , vol.12 , pp. 19
- Collins, P.¹

118
- 0021025352
- (1983) J. Antimicrob. Chemother. , vol.12 , pp. 9
- Elion, G.B.¹

119
- 0018251481
- (1978) J. Biol. Chem. , vol.253 , pp. 8721
- Fyfe, J.A.¹ Keller, P.M.² Furman, P.A.³ Miller, R.L.⁴ Elion, G.B.⁵

120
- 0019321437
- (1980) J. Biol. Chem. , vol.255 , pp. 7204
- Miller, W.H.¹ Miller, R.L.²

121
- 0020408238
- (1982) Biochem. Pharmacol. , vol.31 , pp. 3879
- Miller, W.H.¹ Miller, R.L.²

122
- 0019777091
- (1981) Antimicrob. Agents Chemother. , vol.20 , pp. 518
- Furman, P.A.¹ de Miranda, P.² St. Clair, M.H.³ Elion, G.B.⁴

123
- 0022350376
- (1985) J. Biol. Chem. , vol.260 , pp. 8664
- Keller, P.M.¹ McKee, S.A.² Fyfe, J.A.³

124
- 0018733296
- (1979) J. Virol. , vol.32 , pp. 72
- Furman, P.A.¹ St. Clair, M.H.² Fyfe, J.A.³ Rideout, J.L.⁴ Keller, P.M.⁵ Elion, G.B.⁶

125
- 0019257150
- (1980) Antimicrob. Agents Chemother. , vol.18 , pp. 741
- St. Clair, M.H.¹ Furman, P.A.² Lubbers, C.M.³ Elion, G.B.⁴

126
- 0342385015
- J. Mills, L. Corey, Elsevier, New York
- (1986) Antiviral Chemotherapy: New Directions for Clinical Application and Research , pp. 118-137
- Elion, G.B.¹

127
- 0021230407
- (1984) Antimicrob. Agents Chemother. , vol.25 , pp. 507
- McGuirt, P.V.¹ Shaw, J.E.² Elion, G.B.³ Furman, P.A.⁴

128
- 0021191524
- (1984) J. Biol. Chem. , vol.259 , pp. 9575
- Furman, P.A.¹ St. Clair, M.H.² Spector, T.³

129
- 0019818628
- (1981) Biochem. Pharmacol. , vol.30 , pp. 3071
- Keller, P.M.¹ Fyfe, J.A.² Beauchamp, L.³ Lubbers, C.M.⁴ Furman, P.A.⁵ Schaeffer, H.J.⁶ Elion, G.B.⁷

130
- 0018852875
- (1980) Proc. Natl. Acad. Sci. USA , vol.77 , pp. 2270
- Schnipper, L.E.¹ Crumpacker, C.S.²

131
- 0019869763
- (1981) J. Viroi. , vol.40 , pp. 936
- Furman, P.A.¹ Coen, D.M.² St. Clair, M.H.³ Schaffer, P.A.⁴

132
- 0019932369
- (1982) Am. J. Med. , vol.73 , pp. 383
- Biron, K.K.¹ Fyfe, J.A.² Noblin, J.E.³ Elion, G.B.⁴

133
- 0018889782
- (1980) Virology , vol.102 , pp. 420
- Furman, P.A.¹ McGuirt, P.V.² Keller, P.M.³ Fyfe, J.A.⁴ Elion, G.B.⁵

134
- 0021022096
- (1983) J. Antimicrob. Chemother. , vol.12 , pp. 113
- Pagano, J.S.¹ Sixbey, J.W.² Lin, J.‐C.³

135
- 0020261015
- (1982) Biochem. Biophys. Res. Commun. , vol.108 , pp. 1716
- Ashton, W.T.¹ Karkas, J.D.² Field, A.K.³ Tolman, R.L.⁴

136
- 0021055765
- (1983) J. Biol. Chem. , vol.258 , pp. 12460
- Cheng, Y.C.¹ Grill, S.P.² Dutschman, G.E.³ Narayama, K.⁴ Bastow, K.F.⁵

137
- 0021807545
- (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 2473
- Biron, K.K.¹ Stanat, S.C.² Sorrell, J.B.³ Fyfe, J.A.⁴ Keller, P.M.⁵ Lambe, C.U.⁶ Nelson, D.J.⁷

138
- 0019812773
- (1981) J. Pharmacol. Exp. Ther. , vol.219 , pp. 309
- de Miranda, P.¹ Krasny, H.C.² Page, D.A.³ Elion, G.B.⁴

139
- 0019640845
- (1981) Clin. Pharmacol Ther. (St. Louis) , vol.30 , pp. 662
- de Miranda, P.¹ Good, S.S.² Laskin, O.L.³ Krasny, H.C.⁴ Connor, J.D.⁵ Lietman, P.S.⁶

140
- 0019904665
- (1982) Am. J. Med. , vol.73 , pp. 215
- de Miranda, P.¹ Good, S.S.² Krasny, H.C.³ Connor, J.D.⁴ Laskin, O.L.⁵ Lietman, P.S.⁶

141
- 0019913589
- (1982) Am. J. Med. , vol.73 , pp. 91
- Good, S.S.¹ de Miranda, P.²

142
- 0018619586
- (1979) Clin. Pharmacol. Ther. (St. Louis) , vol.26 , pp. 718
- de Miranda, P.¹ Whitley, R.J.² Blum, M.R.³ Keeney, R.E.⁴ Barton, N.⁵ Cocchetto, D.M.⁶ Good, S.⁷ Hemstreet, G.P.⁸ Kirk, L.E.⁹ Page, D.A.¹⁰ Elion, G.B.¹¹

143
- 0021089633
- (1983) J. Antimicrob. Chemother. , vol.12 , pp. 29
- de Miranda, P.¹ Blum, M.R.²

144
- 0019919014
- (1982) Am. J. Med. , vol.73 , pp. 186
- Blum, M.R.¹ Liao, S.H.T.² de Miranda, P.³

145
- 0019932361
- (1982) Am. J. Med. , vol.73 , pp. 27
- Tucker, W.E.¹

146
- 0021807511
- (1985) Cancer Res. , vol.45 , pp. 2943
- Elion, G.B.¹

147
- 0021083645
- (1983) J. Antimicrob. Chemother. , vol.12 , pp. 79
- Corey, L.¹ Benedetti, J.² Critchlow, C.³ Mertz, G.⁴ Douglas, J.⁵ Fife, K.⁶ Fahnlander, A.⁷ Remington, M.L.⁸ Winter, C.⁹ Dragavon, J.¹⁰

148
- 84990137845
- Lancet , vol.1982 , Issue.2 , pp. 571
- Nilsen, A.E.¹ Aasen, T.² Halsos, A.M.³ Kinge, B.R.⁴ Tjotta, E.A.L.⁵ Wikstrom, K.⁶ Fiddian, A.P.⁷

149
- 0020567567
- (1983) N. Engl. J. Med. , vol.308 , pp. 916
- Bryson, Y.J.¹ Dillon, M.² Lovett, M.³ Acuna, G.⁴ Taylor, S.⁵ Cherry, J.D.⁶ Johnson, B.L.⁷ Wiesmeier, E.⁸ Creagh‐Kirk, T.⁹ Keeney, R.¹⁰

150
- 84935315195
- (1984) JAMA J. Am. Med. Assoc. , vol.251 , pp. 2103
- Reichman, R.C.¹ Badger, G.J.² Mertz, G.J.³ Corey, L.⁴ Richman, D.D.⁵ Connor, J.D.⁶ Redfield, D.⁷ Savoia, M.C.⁸ Oxman, M.N.⁹ Bryson, Y.¹⁰ Tyrrell, D.¹¹ Portnoy, J.¹² Creagh‐Kirk, T.¹³ Keeney, R.E.¹⁴ Ashikaga, T.¹⁵ Dolin, R.¹⁶

151
- 0023767079
- (1988) Am. J. Med. , vol.85 , pp. 14
- Mertz, G.J.¹ Eron, L.² Kaufman, R.³ Goldberg, L.⁴ Raab, B.⁵ Conant, M.⁶ Mills, J.⁷ Kurtz, T.⁸ Davis, L.G.⁹

152
- 0023789971
- (1988) Am. J. Med. , vol.85 , pp. 20
- Mattison, H.R.¹ Reichman, R.C.² Benedetti, J.³ Bolgiano, D.⁴ Davis, L.G.⁵ Bailey‐Farchione, A.⁶ Remington, M.⁷ Winter, C.⁸ Corey, L.⁹

153
- 84990082098
- Lancet , vol.1982 , Issue.2 , pp. 118
- Bean, B.¹ Braun, C.²

154
- 0021071577
- (1983) J. Antimicrob. Chemother. , vol.12 , pp. 169
- Balfour, H.H.¹ McMonigal, K.A.² Bean, B.³

155
- 0019933062
- (1982) Am. J. Med. , vol.73 , pp. 229
- Meyers, J.D.¹ Wade, J.C.² Mitchell, C.D.³ Saral, R.⁴ Lietman, P.S.⁵ Durack, D.T.⁶ Levin, M.J.⁷ Segreti, A.C.⁸ Balfour, H.H.⁹

156
- 0020042788
- (1982) Ann. Intern. Med. , vol.96 , pp. 265
- Wade, J.C.¹ Newton, B.² McLaren, C.³ Fluornoy, N.⁴ Keeney, R.E.⁵ Meyers, J.D.⁶

157
- 0019842283
- (1981) N. Engl. J. Med. , vol.305 , pp. 63
- Saral, R.¹ Burns, W.H.² Laskin, O.L.³ Santos, G.W.⁴ Lietman, P.S.⁵

158
- 0021055309
- (1983) Ann. Intern. Med. , vol.99 , pp. 773
- Saral, R.¹ Ambinder, R.F.² Burns, W.H.³ Angelopulos, C.M.⁴ Griffin, D.E.⁵ Burke, P.J.⁶ Lietman, P.S.⁷

159
- 84990074986
- II
- Lancet , vol.1984 , pp. 707
- Sköldenberg, B.¹ Forsgren, M.² Alestig, K.³ Bergstrom, T.⁴ Burman, L.⁵ Dahlgvist, E.⁶ Forkman, A.⁷ Fryden, A.⁸ Lovgren, K.⁹ Norlin, K.¹⁰ Norrby, R.¹¹ Olding‐Stenkvist, E.¹² Stiernstedt, J.¹³ Uhnoo, I.¹⁴ DeVahl, K.¹⁵

160
- 0022645112
- (1986) N. Engl. J. Med. , vol.314 , pp. 144
- Whitley, R.J.¹ Alford, C.A.² Hirsch, M.S.³ Schooley, R.T.⁴ Luby, J.P.⁵ Aoki, F.Y.⁶ Hanley, D.⁷ Nahmias, A.J.⁸ Soong, S.J.⁹

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