Effects of Protein Malnutrition and Endotoxin on the Intestinal Mucosal Barrier to the Translocation of Indigenous Flora in Mice

Journal of Parenteral and Enteral Nutrition

Volumn 13, Issue 6, 1989, Pages 572-578

  Li, Ma ^a   Specian, Robert D ^a   Berg, Rodney D ^a   Deitch, Edwin A ^a  

^a LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTOXIN;

ANIMAL EXPERIMENT; ARTICLE; HISTOLOGY; MALNUTRITION; MEMBRANE PERMEABILITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN METABOLISM;

ANIMAL; BACTERIAL PHYSIOLOGY; ENDOTOXINS; FEMALE; GASTROINTESTINAL SYSTEM; INTESTINAL MUCOSA; MICE; MICE, INBRED STRAINS; PROTEIN DEFICIENCY; SPECIFIC PATHOGEN-FREE ORGANISMS; SUPPORT, U.S. GOV'T, P.H.S.;

ANIMALIA; BACTERIA (MICROORGANISMS);

EID: 0024355459     PISSN: 01486071     EISSN: 19412444     Source Type: Journal    
DOI: 10.1177/0148607189013006572     Document Type: Article

References (29)

1. Berg RD, Garlington AW: Translocation of certain indigenous bacteria from the gastrointestinal tract to the mesenteric lymphy nodes and other organs in a gnotobiotic mouse model. Infect Immun 23: 403-411, 1979
2. Deitch EA, Maejima K., Berg R.: Effect of oral antibiotics and bacterial overgrowth on the translocation of the GI tract microflora in burned rats. J Trauma 25: 385-392, 1985
3. Berg RD: Inhibition of Escherichia coli translocation from the gastrointestinal tract by normal cecal floral in gnotobiotic or antibiotic-decontaminated mice. Infect Immun 29: 1073-1081, 1980
4. Deitch EA, Winterton J., Berg R.: Deficiency of T cell-mediated immunity promotes bacterial translocation from the GI tract after thermal injury. Arch Surg 121: 97-101, 1986
5. Morehouse J., Specian R., Stewart J., et al: Promotion of the translocation of indigenous bacteria of mice from the GI tract by oral ricinoleic acid. Gastroenterology 91: 673-682, 1986
6. Deitch EA, Bridges RM: Effect of stress and trauma on bacterial translocation from the gut. J Surg Res 42: 536-542, 1987
7. Deitch EA, Berg R.: Endotoxin but not malnutrition promotes bacterial translocation of the gut flora in burned mice. J Trauma 27: 161-166, 1987
8. Chandra RK: Nutrition infection and immunity: Present knowledge and future directions. Lancet 1: 688-691, 1983
9. Deitch EA, Winterton J., Li M., et al: The gut as portal of entry for bacteremia: Role of protein malnutrition. Ann Surg 205: 681-692, 1987
10. Tankaro J.: Intestinal changes in protein-deficient rats. Exp Mol Pathol 3: 224-231, 1964
11. Hill RB Jr, Prosper J., Hirshfield JS, et al: Protein starvation and the small intestine. I. The growth and morphology of the small intestine in weanling rats. Exp Mol Pathol 8: 66-74, 1968
12. Sherman P., Forstner J., Roomi N., et al: Mucin depletion in the intestine of malnourished rats. Am J Physiol 248:(Gastrointest Liver Physiol 11):G418-G423, 1985
13. Syme G.: The effect of protein-deficient isoenergetic diets on the growth of rat jejunal mucosa. Br J Nutr 84: 25-36, 1982
14. Deitch EA, Winterton J., Berg R.: Effect of starvation, malnutrition, and trauma on the gastrointestinal tract flora and bacterial translocation. Arch Surg 122: 1019-1024, 1987
15. Smythe PM, Schonland M., Brereton-Stiles GG, et al: Thymolymphatic deficiency and depression of cell-mediated immunity in protein-calorie malnutrition. Lancet 2: 939-943, 1971
16. Keusch GT, Douglas SD, Hammer G., et al: Antibacterial functions of macrophages in experimental protein-calorie malnutrition. II. Cellular and humoral factors for chemotaxis, phagocytosis, and intracellular bacteriacidal activity. J Infect Dis 138: 134-142, 1978
17. Chaudry IH, Schleck S., Kovacs KF, et al: Effect of prolonged starvation on reticuloendothelial function and survival following trauma. J Trauma 21: 604-611, 1981
18. Kudsk KA, Stone JM, Carpenter G., et al: Enteral and parenteral feeding influences mortality after hemoglobin E. coli peritonitis in normal rats. J Trauma 23: 605-609, 1983
19. Kudsk KA, Stone JM, Carpenter G.: Effects of enteral versus parenteral feeding on body composition of malnourished animals. J Trauma 22: 904-906, 1982
20. Peterson SR, Kudsk KA, Carpenter G., et al: Malnutrition and immunocompetence: Increased mortality following an infectious challenge during hyperalimentation. J Trauma 21: 528-533, 1981
21. Nolan JP, Hare DK, McDevitt JJ, Ali MV: In vitro studies of intestinal endotoxin absorption. I. Kinetic absorption in the isolated everted gut sac. Gastroenterology 72: 434-439, 1977
22. Walker RI, Porvasznik MJ: Disruption of the permeability barrier (zone occludens) between intestinal epithelial cells by lethal doses of endotoxin. Infect Immun 21: 655-658, 1982
23. McDermott MR, Mark DA, Befus AD, et al: Impaired intestinal localization of mesenteric lymphoblasts associated with vitamin A deficiency and protein-calorie malnutrition. Immunology 45: 1-5, 1982
24. Morrison DC, Ryan JL: Bacterial endotoxins and host immune responses. Adv Immunol 28: 293-450, 1979
25. Lyscom N., Brueton MJ: Intraepithelial, lamina propria and Peyer's patch lymphocytes of the rat small intestine. Immunology 45: 775-783, 1982
26. Deitch EA, Bridges W., Baker J., et al: Hemorrhagic shock-induced bacterial translocation is reduced by xanthine oxidase inhibition or inactivation. Surgery 104: 191-198, 1988
27. Bodey GP: Antibiotic prophylaxis in cancer patients: Regimens of oral, nonabsorbable antibiotics for prevention of infection during induction of remission. Rev Infect Dis 3(suppl):S259-S268, 1981
28. Cesario TL, Slater LM, Armentrout SA, et al: Septicemia in acute leukemia. Med Pediatr Oncol 5: 193-203, 1978
29. Border JR, Hassett J., LaDuca J., et al: The gut origin septic states in blunt multiple trauma (ISS=40) in the ICU. Ann Surg 206: 427-448, 1987