메뉴 건너뛰기




Volumn 321, Issue 6, 1989, Pages 337-343

Early Metabolic Defects in Persons at Increased Risk for Non-Insulin-Dependent Diabetes Mellitus

Author keywords

[No Author keywords available]

Indexed keywords

RADIOISOTOPE;

EID: 0024348996     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJM198908103210601     Document Type: Article
Times cited : (806)

References (47)
  • 1
    • 0017250908 scopus 로고
    • Nonketotic diabetes mellitus: insulin deficiency or insulin resistance?
    • Reaven GM, Bernstein R, Davis B, Olefsky JM. Nonketotic diabetes mellitus: insulin deficiency or insulin resistance? Am J Med 1976; 60: 80–8.
    • (1976) Am J Med , vol.60 , pp. 80-88
    • Reaven, G.M.1    Bernstein, R.2    Davis, B.3    Olefsky, J.M.4
  • 2
    • 0024026298 scopus 로고
    • The triumvirate: β-cell, muscle, liver: a collusion responsible for NIDDM
    • DeFronzo RA. The triumvirate: β-cell, muscle, liver: a collusion responsible for NIDDM. Diabetes 1988; 37: 667–87.
    • (1988) Diabetes , vol.37 , pp. 667-687
    • DeFronzo, R.A.1
  • 3
    • 0021106597 scopus 로고
    • Insulin resistance in noninsulin-dependent diabetes mellitus: does it exist and can it be measured?
    • Reaven GM. Insulin resistance in noninsulin-dependent diabetes mellitus: does it exist and can it be measured? Am J Med 1983; 74: 3–17.
    • (1983) Am J Med , vol.74 , pp. 3-17
    • Reaven, G.M.1
  • 4
    • 0023916553 scopus 로고
    • Abnormal patterns of insulin secretion in non-insulin-dependent diabetes mellitus
    • Polonsky KS, Given BD, Hirsch LJ, et al. Abnormal patterns of insulin secretion in non-insulin-dependent diabetes mellitus. N Engl J Med 1988; 318: 1231–9.
    • (1988) N Engl J Med , vol.318 , pp. 1231-1239
    • Polonsky, K.S.1    Given, B.D.2    Hirsch, L.J.3
  • 5
    • 0015504632 scopus 로고
    • Insulin excess as the initial lesion in diabetes
    • Jackson WP, Van Mieghem W, Keller P. Insulin excess as the initial lesion in diabetes. Lancet 1972; 1: 1040–4.
    • (1972) Lancet , vol.1 , pp. 1040-1044
    • Jackson, W.P.1    Van Mieghem, W.2    Keller, P.3
  • 6
    • 0015922861 scopus 로고
    • Dose–response relation between plasma-insulin and blood-glucose levels during oral glucose loads in prediabetic and diabetic subjects
    • Cerasi E, Efendic S, Luft R. Dose–response relation between plasma-insulin and blood-glucose levels during oral glucose loads in prediabetic and diabetic subjects. Lancet 1973; 1: 794–7.
    • (1973) Lancet , vol.1 , pp. 794-797
    • Cerasi, E.1    Efendic, S.2    Luft, R.3
  • 7
    • 85023241307 scopus 로고
    • Insulin responses to oral carbohydrate in true prediabetics and matched controls
    • Savage PJ, Gorden P, Bennett PH, Miller M. Insulin responses to oral carbohydrate in true prediabetics and matched controls. Lancet 1975; 1: 3002.
    • (1975) Lancet , vol.1 , pp. 3002
    • Savage, P.J.1    Gorden, P.2    Bennett, P.H.3    Miller, M.4
  • 9
    • 0019774153 scopus 로고
    • On the pathogenesis of maturity-onset diabetes
    • Luft R, Wajngot A, Efendic S. On the pathogenesis of maturity-onset diabetes. Diabetes Care 1981; 4: 58–63.
    • (1981) Diabetes Care , vol.4 , pp. 58-63
    • Luft, R.1    Wajngot, A.2    Efendic, S.3
  • 10
    • 0019774156 scopus 로고
    • Quantitative and qualitative changes in the early insulin response to glucose in subjects with impaired carbohydrate tolerance
    • Ratzmann KP, Schulz B, Heinke P, Michaelis D. Quantitative and qualitative changes in the early insulin response to glucose in subjects with impaired carbohydrate tolerance. Diabetes Care 1981; 4: 85–91.
    • (1981) Diabetes Care , vol.4 , pp. 85-91
    • Ratzmann, K.P.1    Schulz, B.2    Heinke, P.3    Michaelis, D.4
  • 11
    • 0022623832 scopus 로고
    • Hyperinsulinemia in a population at high risk for non-insulin-dependent diabetes mellitus
    • Haffner SM, Stern MP, Hazuda HP, Pugh JA, Patterson JK. Hyperinsulinemia in a population at high risk for non-insulin-dependent diabetes mellitus. N Engl J Med 1986; 315: 220–4.
    • (1986) N Engl J Med , vol.315 , pp. 220-224
    • Haffner, S.M.1    Stern, M.P.2    Hazuda, H.P.3    Pugh, J.A.4    Patterson, J.K.5
  • 13
    • 0023924773 scopus 로고
    • Impaired glucose tolerance as a disorder of insulin action: longitudinal and cross-sectional studies in Pima Indians
    • Lillioja S, Mott DM, Howard BV, et al. Impaired glucose tolerance as a disorder of insulin action: longitudinal and cross-sectional studies in Pima Indians. N Engl J Med 1988; 318: 1217–25.
    • (1988) N Engl J Med , vol.318 , pp. 1217-1225
    • Lillioja, S.1    Mott, D.M.2    Howard, B.V.3
  • 14
    • 0023951171 scopus 로고
    • Impaired pulsatile secretion of insulin in relatives of patients with non-insulin-dependent diabetes
    • O'Rahilly S, Turner RC, Matthews DR. Impaired pulsatile secretion of insulin in relatives of patients with non-insulin-dependent diabetes. N Engl J Med 1988; 318: 1225–30.
    • (1988) N Engl J Med , vol.318 , pp. 1225-1230
    • O'Rahilly, S.1    Turner, R.C.2    Matthews, D.R.3
  • 16
    • 0037992274 scopus 로고
    • Genetics of diabetes
    • In: Alberti KGMM, Krall LP, eds. Amsterdam: Elsevier
    • Leslie RDG, Pyke DA. Genetics of diabetes. In: Alberti KGMM, Krall LP, eds. Diabetes annual 3. Amsterdam: Elsevier, 1987:39–54.
    • (1987) Diabetes annual 3. , pp. 39-54
    • Leslie, R.D.G.1    Pyke, D.A.2
  • 19
    • 0000886435 scopus 로고
    • Genetics of type 2A- and type 2Bdiabetes mellitus
    • abstract.
    • Köbberling J, Tillil H, Lorenz HJ. Genetics of type 2A- and type 2Bdiabetes mellitus. Diabetes Res Clin Pract 1985; 11: Suppl 1: S311. abstract.
    • (1985) Diabetes Res Clin Pract , vol.11 , pp. S311
    • Köbberling, J.1    Tillil, H.2    Lorenz, H.J.3
  • 20
    • 85023229212 scopus 로고
    • Diabetes mellitus. Technical report series. No. 727. Geneva: World Health Organization, 1985.
    • (1985)
  • 21
    • 0018520840 scopus 로고
    • Glucose clamp technique: a method for quantifying insulin secretion and resistance
    • DeFronzo RA, Tobin JD, Andres R. Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am J Physiol 1979; 237: E214–E223.
    • (1979) Am J Physiol , vol.237 , pp. E214-E223
    • DeFronzo, R.A.1    Tobin, J.D.2    Andres, R.3
  • 22
    • 0023930822 scopus 로고
    • The theoretical bases of indirect calorimetry: a review
    • Ferrannini E. The theoretical bases of indirect calorimetry: a review. Metabolism 1988; 37: 287–301.
    • (1988) Metabolism , vol.37 , pp. 287-301
    • Ferrannini, E.1
  • 24
    • 0023229372 scopus 로고
    • Non-steady state: error analysis of Steele's model and developments for glucose kinetics
    • Cobelli C, Mari A, Ferrannini E. Non-steady state: error analysis of Steele's model and developments for glucose kinetics. Am J Physiol 1987; 252: E679–E689.
    • (1987) Am J Physiol , vol.252 , pp. E679-E689
    • Cobelli, C.1    Mari, A.2    Ferrannini, E.3
  • 25
    • 0000648085 scopus 로고
    • Influences of glucose loading and of injected insulin on hepatic glucose output
    • Steele R. Influences of glucose loading and of injected insulin on hepatic glucose output. Ann NY Acad Sci 1959; 82: 420–30.
    • (1959) Ann NY Acad Sci , vol.82 , pp. 420-430
    • Steele, R.1
  • 26
    • 0003565214 scopus 로고
    • BMDP statistical software manual
    • Berkeley, Calif.: University of California Press
    • Dixon WJ, ed. BMDP statistical software manual. Berkeley, Calif.: University of California Press, 1985.
    • (1985)
    • Dixon, W.J.1
  • 27
    • 0019415752 scopus 로고
    • Receptor and postreceptor defects contribute to the insulin resistance in noninsulin-dependent diabetes mellitus
    • Kolterman OG, Gray RS, Griffin J, et al. Receptor and postreceptor defects contribute to the insulin resistance in noninsulin-dependent diabetes mellitus. J Clin Invest 1981; 68: 957–69.
    • (1981) J Clin Invest , vol.68 , pp. 957-969
    • Kolterman, O.G.1    Gray, R.S.2    Griffin, J.3
  • 28
    • 0023726257 scopus 로고
    • Oxidative and non-oxidative glucose metabolism in non-obese type 2 (non-insulin-dependent) diabetic patients
    • Golay A, DeFronzo RA, Ferrannini E, et al. Oxidative and non-oxidative glucose metabolism in non-obese type 2 (non-insulin-dependent) diabetic patients. Diabetologia 1988; 31: 585–91.
    • (1988) Diabetologia , vol.31 , pp. 585-591
    • Golay, A.1    DeFronzo, R.A.2    Ferrannini, E.3
  • 29
    • 0021691098 scopus 로고
    • Relationships between insulin secretion, insulin action, and fasting plasma glucose concentration in nondiabetic and noninsulin-dependent diabetic subjects
    • Bogardus C, Lillioja S, Howard BV, Reaven G, Mott D. Relationships between insulin secretion, insulin action, and fasting plasma glucose concentration in nondiabetic and noninsulin-dependent diabetic subjects. J Clin Invest 1984; 74: 1238–46.
    • (1984) J Clin Invest , vol.74 , pp. 1238-1246
    • Bogardus, C.1    Lillioja, S.2    Howard, B.V.3    Reaven, G.4    Mott, D.5
  • 30
    • 4244002644 scopus 로고
    • Diminished insulin sensitivity in normoglycemic offspring of two non-insulin-dependent diabetic parents
    • abstract.
    • Warram J, Martin B, Soeldner JS. Diminished insulin sensitivity in normoglycemic offspring of two non-insulin-dependent diabetic parents. Diabetes 1988; 37: Suppl 1: 9A. abstract.
    • (1988) Diabetes , vol.37 , pp. 9A
    • Warram, J.1    Martin, B.2    Soeldner, J.S.3
  • 31
    • 0023640773 scopus 로고
    • In vivo insulin action is familial characteristic in nondiabetic Pima Indians
    • Lillioja S, Mott DM, Zawadzki JK, et al. In vivo insulin action is familial characteristic in nondiabetic Pima Indians. Diabetes 1987; 36: 1329–35.
    • (1987) Diabetes , vol.36 , pp. 1329-1335
    • Lillioja, S.1    Mott, D.M.2    Zawadzki, J.K.3
  • 32
    • 0022450553 scopus 로고
    • Beta-cell dysfunction, rather than insulin insensitivity, is the primary defect in familial type 2 diabetes
    • O'Rahilly SP, Nugent Z, Rudenski AS, et al. Beta-cell dysfunction, rather than insulin insensitivity, is the primary defect in familial type 2 diabetes. Lancet 1986; 2: 360–4.
    • (1986) Lancet , vol.2 , pp. 360-364
    • O'Rahilly, S.P.1    Nugent, Z.2    Rudenski, A.S.3
  • 33
    • 0018758830 scopus 로고
    • An attempt to define the nature of chemical diabetes using a multidimensional analysis
    • Reaven GM, Miller RG. An attempt to define the nature of chemical diabetes using a multidimensional analysis. Diabetologia 1979; 16: 17–24.
    • (1979) Diabetologia , vol.16 , pp. 17-24
    • Reaven, G.M.1    Miller, R.G.2
  • 34
    • 0021258643 scopus 로고
    • Correlation between muscle glycogen synthase activity and in vivo insulin action in man
    • Bogardus C, Lillioja S, Stone K, Mott D. Correlation between muscle glycogen synthase activity and in vivo insulin action in man. J Clin Invest 1984; 73: 1185–90.
    • (1984) J Clin Invest , vol.73 , pp. 1185-1190
    • Bogardus, C.1    Lillioja, S.2    Stone, K.3    Mott, D.4
  • 35
    • 0019935341 scopus 로고
    • The effect of graded doses of insulin on total glucose uptake, glucose oxidation, and glucose storage in man
    • Thiebaud D, Jacot E, DeFronzo RA, Maeder E, Jequier E, Felber JP. The effect of graded doses of insulin on total glucose uptake, glucose oxidation, and glucose storage in man. Diabetes 1982; 31: 957–63.
    • (1982) Diabetes , vol.31 , pp. 957-963
    • Thiebaud, D.1    Jacot, E.2    DeFronzo, R.A.3    Maeder, E.4    Jequier, E.5    Felber, J.P.6
  • 36
    • 50549202600 scopus 로고
    • The glucose fatty-acid cycle: its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus
    • Randle PJ, Garland PB, Hales CN, Newsholme EA. The glucose fatty-acid cycle: its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus. Lancet 1963; 1: 785–9.
    • (1963) Lancet , vol.1 , pp. 785-789
    • Randle, P.J.1    Garland, P.B.2    Hales, C.N.3    Newsholme, E.A.4
  • 38
    • 0023618126 scopus 로고
    • Role of lipid oxidation in pathogenesis of insulin resistance of obesity and type II diabetes
    • Felber JP, Ferrannini E, Golay A, et al. Role of lipid oxidation in pathogenesis of insulin resistance of obesity and type II diabetes. Diabetes 1987; 36: 1341–50.
    • (1987) Diabetes , vol.36 , pp. 1341-1350
    • Felber, J.P.1    Ferrannini, E.2    Golay, A.3
  • 39
    • 0017689690 scopus 로고
    • Unexplained hyperinsulinemia in normal and “prediabetic” Pima Indians compared with normal Caucasians: an example of racial differences in insulin secretion
    • Aronoff SL, Bennett PH, Gorden P, Rushforth N, Miller M. Unexplained hyperinsulinemia in normal and “prediabetic” Pima Indians compared with normal Caucasians: an example of racial differences in insulin secretion. Diabetes 1977; 26: 827–40.
    • (1977) Diabetes , vol.26 , pp. 827-840
    • Aronoff, S.L.1    Bennett, P.H.2    Gorden, P.3    Rushforth, N.4    Miller, M.5
  • 40
    • 0016593484 scopus 로고
    • Hyperinsulinemia and hypoinsulinemia: insulin responses to oral carbohydrate over a wide spectrum of glucose tolerance
    • Savage PJ, Dippe SE, Bennett PH, et al. Hyperinsulinemia and hypoinsulinemia: insulin responses to oral carbohydrate over a wide spectrum of glucose tolerance. Diabetes 1975; 24: 362–8.
    • (1975) Diabetes , vol.24 , pp. 362-368
    • Savage, P.J.1    Dippe, S.E.2    Bennett, P.H.3
  • 41
    • 0018760433 scopus 로고
    • Low insulin response — genetic aspects and implications
    • Luft R, Efendic S. Low insulin response — genetic aspects and implications. Horm Metab Res 1979; 11: 415–23.
    • (1979) Horm Metab Res , vol.11 , pp. 415-423
    • Luft, R.1    Efendic, S.2
  • 42
    • 0021708511 scopus 로고
    • Pancreatic beta cell function in offspring of conjugal diabetic parents: assessment by IRI and C-peptide ratio
    • Snehalatha C, Mohan V, Ramachandran A, Jayashree R, Viswanathan M. Pancreatic beta cell function in offspring of conjugal diabetic parents: assessment by IRI and C-peptide ratio. Horm Metab Res 1984; 16: Suppl: 142–4.
    • (1984) Horm Metab Res , vol.16 , pp. 142-144
    • Snehalatha, C.1    Mohan, V.2    Ramachandran, A.3    Jayashree, R.4    Viswanathan, M.5
  • 43
    • 0021674563 scopus 로고
    • Secretion and hepatic removal of insulin in the healthy offspring of type 2 (non-insulin-dependent) diabetic subjects
    • Bonora E, Zavaroni I, Bruschi F, et al. Secretion and hepatic removal of insulin in the healthy offspring of type 2 (non-insulin-dependent) diabetic subjects. Diabete Metab 1984; 10: 250–4.
    • (1984) Diabete Metab , vol.10 , pp. 250-254
    • Bonora, E.1    Zavaroni, I.2    Bruschi, F.3
  • 45
    • 0022868041 scopus 로고
    • Heterogeneity of insulin responses: phases leading to type 2 (non-insulin-dependent) diabetes mellitus in the rhesus monkey
    • Hansen BC, Bodkin NL. Heterogeneity of insulin responses: phases leading to type 2 (non-insulin-dependent) diabetes mellitus in the rhesus monkey. Diabetologia 1986; 29: 713–9.
    • (1986) Diabetologia , vol.29 , pp. 713-719
    • Hansen, B.C.1    Bodkin, N.L.2
  • 46
    • 0017154704 scopus 로고
    • The syndromes of insulin resistance and acanthosis nigricans: insulin-receptor disorders in man
    • Kahn CR, Flier JS, Bar RS, et al. The syndromes of insulin resistance and acanthosis nigricans: insulin-receptor disorders in man. N Engl J Med 1976; 294: 739–45.
    • (1976) N Engl J Med , vol.294 , pp. 739-745
    • Kahn, C.R.1    Flier, J.S.2    Bar, R.S.3
  • 47
    • 84912594624 scopus 로고
    • Diabetes, in acromegaly and other endocrine disorders
    • In: DeGroot LJ, Cahill GF Jr, Odell WD, et al., eds. New York: Grune & Stratton
    • Flier JS, Roth J. Diabetes in acromegaly and other endocrine disorders. In: DeGroot LJ, Cahill GF Jr, Odell WD, et al., eds. Endocrinology. Vol. 2. New York: Grune & Stratton, 1979:1085–92.
    • (1979) Endocrinology. , vol.2 , pp. 1085-1092
    • Flier, J.S.1    Roth, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.