Structure of complex of synthetic HIV-1 protease with a substrate-based inhibitor at 2.3 Å resolution

Science

Volumn 246, Issue 4934, 1989, Pages 1149-1152

  Miller, Maria ^a   Schneider, Jens ^b   Sathyanarayana, Bangalore K ^a   Toth, Mihaly V ^c   Marshall, Garland R ^c   Clawson, Leigh ^b   Selk, Linda ^b   Kent, Stephen B H ^b,d   Wlodawer, Alexander ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d BOND UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

PEPTIDE INHIBITOR; PROTEINASE; UNCLASSIFIED DRUG;

ARTICLE; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; NONHUMAN; PRIORITY JOURNAL; ULTRASTRUCTURE;

AMINO ACID SEQUENCE; BINDING SITES; CHEMISTRY, PHYSICAL; CRYSTALLIZATION; ENDOPEPTIDASES; GENE PRODUCTS, GAG; HIV PROTEASE; HIV-1; HYDROGEN BONDING; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; OLIGOPEPTIDES; PROTEASE INHIBITORS; PROTEIN CONFORMATION; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0024344021     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.2686029     Document Type: Article

References (21)