Interaction of tRNA with 23S rRNA in the ribosomal A, P, and E sites

Cell

Volumn 57, Issue 4, 1989, Pages 585-597

  Moazed, Danesh ^a   Noller, Harry F ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORAMPHENICOL; RIBOSOME RNA; TRANSFER RNA;

GENETIC ENGINEERING; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS;

BASE SEQUENCE; ESCHERICHIA COLI; RIBOSOMES; RNA, BACTERIAL; RNA, RIBOSOMAL; RNA, RIBOSOMAL, 23S; RNA, TRANSFER; RNA, TRANSFER, AMINO ACYL; SUPPORT, U.S. GOV'T, P.H.S.; TRANSFERASES;

EID: 0024334898     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/0092-8674(89)90128-1     Document Type: Article

References (62)

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2. The binding site for ribosomal protein L2 within 23S ribosomal RNA of Escherichia coli
3. The binding site for protein L1 on 23S ribosomal RNA of Escherichia coli
4. Protection of ribosomal RNA from kethoxal in polyribosomes
5. Mutational alterations in 50S proteins of the Escherichia coli ribosomes
6. Phe to Escherichia coli ribosomes
7. Crosslinking of the anticodon of P site bound tRNA to C-1400 of E. coli 16S RNA does not require the participation of the 50S subunit
8. Sequence at the site of attachment of an affinity-label derivative of puromycin on 23S ribosomal RNA of Escherichia coli ribosomes
9. Translation and translocation of defined RNA messengers
10. 70S ribosomes of E. coli have an additional site for deacylated tRNA binding
11. A compilation of large subunit rRNA sequences presented in a structural format
12. The behaviour of acetylphenylalanyl soluble ribonucleic acid in polyphenylalnine synthesis
13. 3H]-p-azidopuromycin photoaffinity labeling of Escherichia coli ribosomes: evidence for site-specific interactions at U2504 and G2505 in domain V of 23S ribosomal RNA
14. The sequence of reactions leading to the synthesis of a peptide bond on reticulocyte ribosomes
15. Kinetic proofreading a new mechanism for reducing errors in biosynthetic processes requiring high specificity
16. 23S ribosomal RNA mutations in halobacteria conferring resistance to the anti-80S ribosome targeted antibiotic anisomycin
17. Quantitative study of interaction of deacylated tRNA with Escherichia coli ribosomes
18. Aminoacyl tRNA binding at the recognition site is the first step of the elongation cycle of protein synthesis
19. Evolutionary relationships amongst archaebacteria: a comparative study of 23S ribosomal RNAs of a sulfur-dependent extreme thermopile, an extreme halophile, and a thermophilic methanogen
20. Destabilization of codon-anti-codon interaction in the ribosomal exit site
21. tRNA binding sites of ribosomes from Escherichia coli
22. Affinities of tRNA binding sites of ribosomes from Escherichia coli
23. Phe in exit site of Escherichia coli ribosomes
24. Relative affinities of all Escherichia coli aminoacyl-tRNAs for elongation factor Tu-GTP
25. Codon-anticodon interaction at the ribosomal peptidyl-site
26. Action of venom phosphodiesterase on transfer RNA from Escherichia coli
27. Transfer RNA shields specific nucleotides in 16S ribosomal RNA from attack by chemical probes
28. Chloramphenicol, erythromycin, carbomycin and vernamycin B protect overlapping sites in the peptidyl transferase region of 23S ribosomal RNA
29. Rapid chemical probing of conformation in 16S ribosomal RNA and 30S ribosomal subunits using primer extension
30. Interaction of elongation factors EF-G and EF-Tu with a conserved loop in 23S rRNA
31. Ribosome-catalyzed peptidyl transfer: effect of some inhibitors of protein synthesis
32. The peptidyl transferase activity of ribosomes
33. Catalysis of peptidyl transfer by human tonsil ribosomes and effects of some antibiotics
34. Kinetic amplification of enzyme discrimination
35. RNA code words and protein synthesis
36. Structure of ribosomal RNA
37. Secondary structure of 16S ribosomal RNA
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39. Secondary structure model for 23S ribosomal RNA
40. Structure and function of ribosomes and their molecular components
41. Ribosome structure, function, and evolution: ribosomal RNA, proteins, and functional sites in three dimensions
42. Identification of 50S proteins at the peptidyl-tRNA binding site of E. coli ribosomes
43. Structural and functional interactions of tRNA-ribosome complex
44. Allosteric interactions between the ribosomal transfer RNA-binding sites A and E
45. Three tRNA binding sites on Escherichia coli ribosomes
46. Comparison of ribosomal entry and acceptor transfer ribonucleic acid binding sites on Escherichia coli 70S ribosomes
47. Phe
48. Mechanism of ribosomal translocation: tRNA binds transiently to an exit site before leaving the ribosome during translocation
49. Antibiotic resistance mutations in 16S and 23S ribosomal RNA genes of Escherichia coli
50. Photo-affinity labeling at the peptidyl transferase centre reveals two different positions for the A- and P-sites in domain V of 23S rRNA
51. Analysis of RNA structure using chemical and enzymatic probing monitored by primer extension
52. Immunoelectron microscopy of Escherichia coli ribosomes
53. The puromycin reaction and its relationship to protein synthesis
54. The importance of highly conserved nucleotides in the binding region of chloroamphenicol at the peptidyl transferase centre of Escherichia coli 23S ribosomal RNA
55. Interaction of siomycin with acceptor site of Escherichia coli ribosomes
56. The synthesis of proteins upon ribosomes
57. Binding of transfer ribonucleic acid to ribosomes engaged in protein synthesis: number and properties of ribosomal binding sites
58. tRNA binding to and topographical arrangement on E. coli ribosomes
59. Molecular mechanisms of translocation: a reciprocating ratchet mechanism
60. Mechanism of inhibition of protein synthesis by kirromycin
61. The use of 2-iminothiolane as an RNA-protein cross-linking agent in Escherichia coli ribosomes and the localization on 23S RNA of sites cross-linked to proteins L4 L6 L21 L23 L27 and L29
62. Codon-anticodon interaction at the ribosomal P (peptidyl) site