Roles of Individual Human Cytochrome P-450 Enzymes in the Bioactivation of Benzo(a)pyrene, 7,8-Dihydroxy-7,8-dihydrobenzo(a)pyrene, and Other Dihydrodiol Derivatives of Polycyclic Aromatic Hydrocarbons

Cancer Research

Volumn 49, Issue 22, 1989, Pages 6304-6312

  Shimada, Tsutomu ^a,c   Martin, Martha V ^a   Guengerich, F Peter ^a   Pruess Schwartz, Donna ^b   Marnett, Lawrence J ^b  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WAYNE STATE UNIVERSITY   (United States)

^c OSAKA PREFECTURAL INSTITUTE OF PUBLIC HEALTH   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

7,8 DIHYDRO 7,8 DIHYDROXYBENZO[A]PYRENE; BENZO[A]PYRENE; CYTOCHROME P450; POLYCYCLIC AROMATIC HYDROCARBON; RADIOISOTOPE;

ARTICLE; HUMAN; HUMAN CELL; METABOLIC ACTIVATION; PRIORITY JOURNAL;

7,8-DIHYDRO-7,8-DIHYDROXYBENZO(A)PYRENE 9,10-OXIDE; ANIMAL; BENZO(A)PYRENE; BIOTRANSFORMATION; CYTOCHROME P-450 ENZYME SYSTEM; DIHYDROXYDIHYDROBENZOPYRENES; DNA DAMAGE; GENE EXPRESSION; GENES, STRUCTURAL; HUMAN; ISOENZYMES; KINETICS; LUNG; MICROSOMES; MICROSOMES, LIVER; POLYCYCLIC HYDROCARBONS; RATS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0024326433     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: None     Document Type: Article

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