Radioresistant DNA synthesis and human genetic disease

Human Genetics

Volumn 82, Issue 2, 1989, Pages 113-117

  Young, Babara R ^a   Painter, Robert B ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RADIOISOTOPE;

ALZHEIMER DISEASE; ATAXIA TELANGIECTASIA; CELL CULTURE; DNA SYNTHESIS; DOSE RESPONSE; FIBROBLAST; HEREDITY; HUMAN; PRIORITY JOURNAL; RADIATION RESPONSE; RADIOSENSITIVITY; X RAY;

ATAXIA TELANGIECTASIA; CELLS, CULTURED; DNA; DOSE-RESPONSE RELATIONSHIP, RADIATION; FIBROBLASTS; HUMAN; SUPPORT, U.S. GOV'T, NON-P.H.S.;

EID: 0024313378     PISSN: 03406717     EISSN: 14321203     Source Type: Journal    
DOI: 10.1007/BF00284040     Document Type: Article

References (27)

1. An assessment of the radiosensitivity of ataxia-telangiectasia heterozygotes
2. Radioresistant DNA synthesis in cells of patients showing increased chromosomal sensitivity to ionizing radiation
3. The repair of potentially lethal damage in X-irradiated cultures of normal and ataxia telangiectasia human fibroblasts
4. Subchromosomal DNA synthesis in X-irradiated V-79 cells
5. Unusual levels of (ADP-ribose)n and DNA synthesis in ataxia telangiectasia cells following γ-ray irradiation
6. Isolation and purification of large quantities of DNA replication intermediates by pH step alkaline elution
7. Variant of ataxia-telangiectasia with low-level radio-sensitivity
8. Radiosensitive Down syndrome lymphoblastoid lines have normal ionizing radiation-induced inhibition of DNA synthesis
9. Effect of ionizing radiation on DNA synthesis in ataxia telangiectasia cells
10. Patients with an inherited syndrome characterized by immunodeficiency, microcephaly, and chromosomal instability: genetic relationship to ataxia telangiectasia
11. A derivative of an ataxia-telangiectasia (A-T) cell line with normal radiosensitivity but A-T-like inhibition of DNA synthesis
12. Effect of confluent holding on potentially lethal damage repair, cell cycle progression, and chromosomal aberrations in human normal and ataxia-telangiectasia fibroblasts
13. Effects of ionizing radiations on DNA replication in cultured mammalian cells
14. Differences in replicon behavior between X-irradiation-sensitive L5178Y mouse lymphoma cells and A-T fibroblasts using DNA fiber autoradiography
15. Radioresistant DNA synthesis: an intrinsic feature of ataxia telangiectasia
16. Are lesions induced by ionizing radiation direct blocks to DNA chain elongation?
17. Inhibition of mammalian cell DNA synthesis by ionizing radiation
18. X-ray-induced inhibition of DNA synthesis in Chinese hamster ovary, human HeLa, and mouse L cells
19. Radiosensitivity in ataxia-telangiectasia: a new explanation
20. Cellular hypersensitivity to chronic γ-radiation in cultured fibroblasts from ataxia-telangiectasia heterozygotes
21. The effect of 313 nanometer light on initiation of replicons in mammalian cell DNA containing bromodeoxyuridine
22. Effect of aphidicolin on de novo DNA synthesis, DNA repair and cytotoxicity in γ-irradiated human fibroblasts. Implications for the enhanced radiosensitivity in ataxia telangiectasia
23. Hypersensitivity to ionizing radiation, in vitro, in a new chromosomal breakage disorder, the Nijmegen Breakage Syndrome
24. Evidence that X-irradiation inhibits DNA replicon initiation in Chinese hamster cells
25. Radiation effects on DNA chain growth in mammalian cells
26. The rate of DNA synthesis in normal human and ataxia telangiectasia cells after exposure to X-irradiation