Tyrosine Hydroxylase Content of Residual Striatal Dopamine Nerve Terminals Following 6‐Hydroxydopamine Administration: A Flow Cytometric Study

Journal of Neurochemistry

Volumn 53, Issue 3, 1989, Pages 879-885

  Wolf, Marina E ^a   Zigmond, Michael J ^b   Kapatos, Gregory ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

6 Hydroxydopamine; Flow cytometry; Nigrostriatal dopamine neurons; Synaptosomes; Tyrosine hydroxylase

Indexed keywords

OXIDOPAMINE; TYROSINE 3 MONOOXYGENASE;

ANIMAL CELL; ANIMAL EXPERIMENT; BRAIN INJURY; DOPAMINERGIC NERVE CELL; FLOW CYTOMETRY; NONHUMAN; PRIORITY JOURNAL; SYNAPTOSOME;

ANIMAL; CORPUS STRIATUM; DOPAMINE; FLOW CYTOMETRY; FLUORESCEIN-5-ISOTHIOCYANATE; FLUORESCEINS; FLUORESCENT ANTIBODY TECHNIQUE; FLUORESCENT DYES; HYDROXYDOPAMINES; MALE; NERVE ENDINGS; OXIDOPAMINE; RATS; RATS, INBRED STRAINS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; SYNAPTOSOMES; THIOCYANATES; TYROSINE 3-MONOOXYGENASE;

EID: 0024311918     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.1989.tb11786.x     Document Type: Article

References (38)

1. Short‐ and long‐term changes in tyrosine hydroxylase activity in rat brain after subtotal destruction of central noradrenergic neurons
2. Hyperactivity of DA neurons after partial destruction of nigrostriatal DA system
3. Time course of adaptations in dopamine biosynthesis, metabolism, and release following nigrostriatal lesions: implications for behavioral recovery from brain injury
4. Brain dopamine and the syndromes of parkinsonism and Huntington: clinical, morphological, and neurochemical correlations
5. A rapid, sensitive method for detection of alkaline phosphatase‐conjugated anti‐antibody on western blots
6. Effect of 6‐hydroxydopamine on brain norepinephrine and dopamine: evidence for selective degeneration of catecholamine neurons. J.
7. Dopamine receptors
8. 3H]spiroperidol binding
9. Effects of l‐methyI‐4‐phenyl‐1,2,3,6‐tetrahydropyridine (MPTP) on catecholamines and metabolites in primate brain and CSF
10. Regulation of dopamine synthesis in the medial prefrontal cortex is mediated by release‐modulating autoreceptors: studies in vivo
11. The isolation of nerve endings from brain: an electron‐microscopic study of cell fragments derived bv homogenization and centrifugation
12. Studies in postmortem dopamine uptake. I. Kinetic characterization of the synaptosomal dopamine uptake in rat and human brain after postmortem storage and cryopreservation. Comparison with noradrenaline and serotonin uptake
13. Studies in postmortem dopamine uptake. II. Alterations of the synaptosomal catecholamine uptake in postmortem brain regions in schizophrenia. J.
14. Metabolically active synaptosomes can be prepared from frozen rat and human brain
15. Partial lesions of the nigrostriatal system in rat brain: biochemical characterization
16. In vitro studies on central and peripheral monoamine neurons at the ultrastructural level
17. Electron and fluorescence microscopical studies on the nucleus caudatus putamen of the rat after unilateral lesions of ascending nigro‐neostriatal dopamine neurons
18. The use of autoradiographic techniques for the identification and mapping of transmitter‐specific neurones in CNS
19. Improved technique utilizing nonfat dried milk for analysis of proteins and nucleic acids transferred to nitrocellulose
20. Cleavage of structural proteins during the assemblv of the head of bacteriophage T4
21. The neu‐rochemistry of Parkinson's disease: effect of L‐dopa therapy
22. Restoration of dopaminergic inhibition of cholinergic function after partial damage to the nigro‐striatal bundle
23. Homospecific activity (activity per enzyme protein) of tyrosine hydroxylase increases in Parkinsonian brain
24. 3‐norepinephrine into the lateral ventricle of the rat brain
25. Short‐term effects of dopamine‐depleting brain lesions on spontaneous activity of Type II striatal neurons: relation to local dopamine concentration and behavior
26. A simplification of the protein assay method of Lowry et al. which is more generally applicable
27. Effect of L‐dopa on brain monoamines and their metabolites in Parkinson's disease
28. Normalization of extracellular dopamine in striatum following recovery from a partial unilateral 6‐OHDA lesion of the substantia nigra: a microdialysis study in freely moving rats
29. Homovanillic acid and dihydroxyphenylacetic acid in the striatum of monkeys with brain lesions
30. Increased dopamine efflux from striatal slices during development and after nigrostriatal bundle damage
31. Fixation of ejaculated spermatozoa for electron microscopia
32. Supersensitivity to dopamine agonists following unilateral. 6‐hydroxydopamine‐induced striatal lesions in mice
33. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications
34. Flow cytometric analysis of rat striatal nerve terminals
35. Flow cytometric analysis and isolation of permeabilized dopamine nerve terminals from rat striatum
36. Deficits in feeding behavior after intraventricular injection of 6‐hydroxydopamine in rats
37. Supersensitivity after intraventricular 6‐hydroxydopamine: relation to dopamine depletion
38. Neurochemical compensation after nigrostriatal bundle injury in an animal model of preclinical Parkinsonism