Chemotherapeutic evaluation of glucarate and n-(4-hydroxyphenyl)retinamide alone and in combination in the rat mammary tumor model

Journal of the National Cancer Institute

Volumn 81, Issue 23, 1989, Pages 1820-1823

  Abou issa, Hussein ^a   Webb, Thomas E ^a   Minton, John P ^a   Moeschberger, Melvin ^b  

^a Department of Surgery ^*  (United States)

^b OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FENRETINIDE; SACCHARATE CALCIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST CANCER; DRUG POTENTIATION; FEMALE; GROWTH INHIBITION; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT;

9,10-DIMETHYL-1,2-BENZANTHRACENE; ANIMAL; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; DRUG SYNERGISM; FEMALE; FENRETINIDE; GLUCARIC ACID; MAMMARY NEOPLASMS, EXPERIMENTAL; RATS; RATS, INBRED STRAINS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TRETINOIN;

EID: 0024305973     PISSN: 00278874     EISSN: None     Source Type: Journal    
DOI: 10.1093/jnci/81.23.1820     Document Type: Article

References (27)

1. Moon RC, Itri LM: Retinoids and cancer. In The Retinoids, vol 2 (Sporn MB, Roberts AB, Goodman DS, eds). New York: Academic Press, 1984, pp 327-371
2. Thompson HJ, Herbst EJ, Meeker LP: Chemoprevention of mammary carcinogenesis: A comparative review of the efficacy of a polyamine antimetabolite, retinoids and selenium. JNC1 77:595-598, 1986
3. Moon RC, Grubbs CJ, Sporn MB, et al: Retinylacetate inhibits mammary carcinogenesis induced by /V-methyl-ZV-nitrosourea. Nature 267:620-621, 1977
4. Abou-Issa H, Duruibe VA: Anticarcino- genic effect of retinoids on 7, 12-dimethyl- benz(a)anthracene-induced mammary tumor induction, and its relationship to cyclic AMP-dependent protein kinase. Biochem Biophys Res Commun 135:116-123, 1986
5. Moon RC, Thompson HJ, Becci PJ, et al: A-4-Hydroxyphenyl retinamide, a new retinoid for preventing breast cancer in the rat. Cancer Res 39:1339-1349, 1979
6. Rustin GJ, Eccles SA: The potential use of retinoids in oncology (meeting report). Br J Cancer 51:443-445, 1985
7. Oredipe OA, Barth RF, Hanausek-Walaszek M, et al: Effects of calcium glucarate on the promotion of diethylnitrosamine-initiated altered hepatic foci in rats. Cancer Lett 38:95-99, 1987
8. Walaszek Z, Hanausek-Walaszek M, Webb TE: Dietary glucarate-mediated reduction of sensitivity of murine strains to chemical carcinogenesis. Cancer Lett 33:25-32, 1986
9. Dwtvedi C, Downie AA, Webb TE: Modulation of chemically initiated and promoted skin tumorigenesis in CD-I mice by dietary glucarate. J Environ Pathol Toxicol Oncol. In press
10. Walaszek Z, Hanausek-Walaszek M, Minton JP, et al: Dietary glucarate as antipromoter of 7, 12-dimethylbenz(a)anthra- cene-induced mammary tumorigenesis. Carcinogenesis 7:1463-1466, 1986
11. Marsh CA: Metabolism of D-glucuronolactone in mammalian system. II. Conversion of D-glucuronolactone to D-glucaric acid by tissue preparations. Biochem J 87:82-90, 1963
12. Dwtvedi C, Heck WJ, Downie AA, et al: Effect of calcium glucarate on net glucuronidation. Biochem Med Met Biol. In press
13. 3 Carcinogenesis 9:187-192, 1988
14. Dwtvedi C, Downie AA, Webb TE: Net glucuronidation in different rat strains: Importance of microsomal /J-glucuronidase. FASEBJ 1:303-307, 1987
15. Abou-Issa HM, Durube VA, Minton JP, et al: Putative metabolites derived from dietary combinations of calcium glucarate and (V-(4-hydroxyphenyl)retinamide act synergistically to inhibit the induction of rat mammary tumors by 7, 12-dimethylbenz(a)anthracene. Proc Natl Acad Sci USA 85:4181-4184, 1988
16. Huggins C, Grand LC, Brillantes F: Mammary cancer induced by a single feeding of polynuclear hydrocarbons, and its suppression. Nature 185:204-207, 1961
17. Welsch CW: Rodent models to examine in vivo hormonal regulation of mammary gland tumorigenesis. In Cellular and Molecular Biology of Mammary Cancer (Kidwell W, Heppner G, Anderson E, eds). New York: Plenum Press, 1987, pp 163-179
18. Steel GG: Growth Kinetics of Tumors. London: Oxford Univ Press, 1977, pp 5-25
19. Schuller DE, Abou-Issa H, Parrish R: Estrogen and progesterone receptors in head and neck cancer. Arch Otolaryngol 110:725-727, 1984
20. Scatchard G: The attraction of proteins for small molecules and ions. Ann N Y Acad Sci 51:660-672, 1949
21. Lowry OH, Rosebrough NJ, Farr AL, et al: Protein measurement with the Folin phenol reagent. J Biol Chem 193:265-275, 1951
22. Klurfeld DM, Welch CB, Davis MJ, et al: Determination of degree of energy restriction necessary to reduce DMBA-induced mammary tumorigenesis in rats during the promotion phase. J Nutr 119:286-291, 1989
23. Stolfi RL, Stolfi LM, Sawyer RC, et al: Chemotherapeutic evaluation using clinical criteria in spontaneous autochthonous murine breast tumors. J Natl Cancer Inst 80:52-55, 1988
24. Zile MH, Cullum ME, Simpson RU, et al: Induction of differentiation of human promyelocytic leukemia cell line HL-60 by retinoyl glucuronide, a biologically active metabolite of vitamin A. Proc Natl Acad Sci USA 84:2208-2212, 1987
25. Gallup JM, Barua AB, Furr HC, et al: Effects of retinoid /S-glucuronides and N- retinoylamines on differentiation of HL-60 cells in vitro. Proc Soc Exp Biol Med 186:269-294, 1987
26. Cho-Chung YS: Modes of tumor regression. Rev Endocrine-Related Cancer 28:13-18, 1988
27. The United States Pharmacopiea Conventional, Inc. United States Pharmacopeia. 20th rev. Easton, PA: Mack Printing Co., 1980, p 108