Structure of the β subunit of translational initiation factor elF-2

Cell

Volumn 54, Issue 5, 1988, Pages 633-639

  Pathak, Vinay K ^a   Nielsen, Peter J ^b   Trachsel, Hans ^c   Hershey, John W B ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b MAX PLANCK INSTITUTE OF IMMUNOBIOLOGY AND EPIGENETICS   (Germany)

^c UNIVERSITY OF BERN   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; INITIATION FACTOR; INITIATION FACTOR 2; PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; COMPARATIVE STUDY; FUNGAL GENE; GENETICS; HUMAN; ISOLATION AND PURIFICATION; MACROMOLECULE; MOLECULAR CLONING; MOLECULAR GENETICS; NUCLEIC ACID HYBRIDIZATION; NUCLEOTIDE SEQUENCE; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY; SPECIES DIFFERENCE; STRUCTURAL GENE;

AMINO ACID SEQUENCE; BASE SEQUENCE; CLONING, MOLECULAR; COMPARATIVE STUDY; DNA; EUKARYOTIC INITIATION FACTOR-2; GENES, FUNGAL; GENES, STRUCTURAL; HUMAN; MACROMOLECULAR SYSTEMS; MOLECULAR SEQUENCE DATA; NUCLEIC ACID HYBRIDIZATION; PEPTIDE INITIATION FACTORS; PROTEINS; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY, NUCLEIC ACID; SPECIES SPECIFICITY; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0024297795     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(88)80007-2     Document Type: Article

References (44)

1. mRNA cap-binding protein: cloning of the gene encoding protein synthesis initiation factor elF-4E from saccharomyces cerevisiae
2. Affinity labeling of protein synthesis factors
3. Potential metal-binding domains in nucleic acid binding proteins
4. Structure of chromatin
5. Structure and phosphorylation of eukaryotic initiation factor 2
6. GTP binding domain: three consensus sequence elements with distinct spacing
7. The isolation and characterization from rabbit reticulocytes of two forms of eukaryotic initiation factor 2 having different β polypeptides
8. Mutations at a Zinc(II) finger motif in the elF-2β gene in yeast alter translation initiation codon selection during the scanning process
9. Identification and quantitation of levels of protein synthesis initiation factors in crude HeLa cell lysates by two dimensional polyacrylamide gel electrophoresis
10. Heat shock-induced translational alterations in HeLa cells
11. Cloning and sequencing of complementary DNAs encoding the α-subunit of translational initiation factor elF-2
12. Zinc fingers: gilt by association
13. Purification and properties of elF-2 from pig liver
14. Preparation and use of nuclease-treated rabbit reticulocyte lysates for the translation of eukaryotic messenger RNA
15. Structure of the GDP domain of EF-Tu and location of the amino acids homologous to ras oncogene proteins
16. Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes
17. An analysis of 5′-noncoding sequences from 699 vertebrate messenger RNAs
18. Substrate specificity determinants for casein kinase II as deduced from studies with synthetic peptides
19. GTP interacts with the γ subunit of eukaryotic initiation factor elF-2
20. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
21. Characteristics of eukaryotic initiation factor 2 and its subunits
22. Efficient in vitro synthesis of biologically active RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter
23. The purification and characterization of multiple forms of protein synthesis eukaryotic initiation factors 2, 3, and 5 from rabbit reticulocytes
24. A new strategy to create ordered deletions for rapid nucleotide sequencing
25. Eukaryotic protein synthesis
26. Silver stain for proteins in polyacrylamide gels: a modified procedure with enhanced uniform sensitivity
27. Cloning of eukaryotic protein synthesis initiation factor genes: isolation and characterization of cDNA clones encoding factor elF-4A
28. Construction of improved M13 vectors using oligodeoxynucleotide-directed mutagenesis
29. Initiation of protein synthesis in mammalian cells
30. Generation of a mutant form of protein synthesis initiation factor elF-2 lacking the site of phosphorylation by elF-2 kinases
31. Translation in micrococcal nuclease-treated cell-free extracts from Ehrlich ascites tumor cells
32. Methionyl-tRNA synthetase of Escherichia coli
33. Labelling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I
34. Translational control by messenger RNA competition for eukaryotic initiation factor 2
35. Amino acid sequence of the mRNA cap-binding protein from human tissues
36. 2B or not 2B: regulation of the catalytic utilization of elF-2
37. DNA sequencing with chain-terminating inhibitors
38. Purified eukaryotic initiation factor 2 consists of two polypeptide chains of 48,000 and 38,000 daltons
39. Detection of metal ions by gas capillary gas-chromatographic seperation of their volatile chelates
40. Site-specific phosphorylation of initiation factor 2 by three cyclic nucleotide-independent protein kinases
41. The control of the rate of initiation of eukaryotic protein synthesis
42. The NH2-terminal sequence of the α and γ subunits of eukaryotic initiation factor 2 and the phosphorylation site for the heme-regulated elF-2α kinase
43. Efficient isolation of genes using antibody probes