Genetic and Crystallographic Studies of the 3′,5′- exonucleolytic site of DNA polymerase I

Science

Volumn 240, Issue 4849, 1988, Pages 199-201

  Derbyshire, Victoria ^a   Freemont, Paul S ^b,c   Sanderson, Mark R ^b,d   Beese, Lorena ^b   Friedman, Jonathan M ^b   Joyce, Catherine M ^a   Steitz, Thomas A ^b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b YALE UNIVERSITY   (United States)

^c IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^d INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DNA DIRECTED DNA POLYMERASE BETA; EXONUCLEASE; METAL;

ARTICLE; BINDING SITE; CATALYSIS; CHEMICAL STRUCTURE; COMPUTER GRAPHICS; CRYSTALLOGRAPHY; ENZYMOLOGY; ESCHERICHIA COLI; GENETICS; NUCLEOTIDE SEQUENCE; PROTEIN CONFORMATION; STRUCTURE ACTIVITY RELATION;

BINDING SITES; CATALYSIS; COMPUTER GRAPHICS; CRYSTALLOGRAPHY; DNA MUTATIONAL ANALYSIS; DNA POLYMERASE I; ESCHERICHIA COLI; EXONUCLEASES; METALS; MODELS, MOLECULAR; PROTEIN CONFORMATION; STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0024281443     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.2832946     Document Type: Article

References (17)