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1
-
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0023648411
-
Current concepts: lymphokines
-
Of interest, Good review of several macrophage-produced factors: IL-1α, IL-1β, G-CSF, GM-CSF, M-CSF, IFN-α, IFN-β (IL-6), TNF-α.
-
(1987)
N Engl J Med
, vol.317
, pp. 940-945
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Dinarello1
Mier2
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2
-
-
0023147156
-
Secretory production of macrophages
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Of interest, A fine review.
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(1987)
J Clin Invest
, vol.79
, pp. 319-326
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Nathan1
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3
-
-
0023257834
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Mouse lymphotoxin and tumor necrosis factor: structural analysis of the cloned genes, physical linkage, and chromosomal position
-
Of interest, Genomic linkage and structure of mouse TNF-α and TNF-β.
-
(1987)
J Immunol
, vol.139
, pp. 476-483
-
-
Gardner1
Mock2
Hilgers3
Huppi4
Roeder5
-
4
-
-
0023874728
-
Tumour necrosis factor-α in murine autoimmune ‘lupus’ nephritis
-
Of interest, A restriction fragment length polymorphism in the TNF-α locus of mice with lupus corresponds to lower levels of TNF-α expression and a high level of disease penetration.
-
(1988)
Nature
, vol.331
, pp. 356-358
-
-
Jacob1
McDevitt2
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5
-
-
0023199874
-
Membrane interleukin 1 induction on human endothelial cells and dermal fibroblasts
-
Of interest, TNF-α induces endothelial cell and fibroblast IL-1.
-
(1987)
J Immunol
, vol.139
, pp. 2317-2324
-
-
Kurt-Jones1
Fiers2
Pober3
-
7
-
-
0023242020
-
C5a induction of human interleukin 1: synergistic effect with endotoxin or interferon-γ
-
Of interest, A macrophage chemoattractant complement split product, C5a, synergizes with inflammatory endotoxin and immune IFN-γ in inducing macrophage IL-1 production.
-
(1987)
J Immunol
, vol.139
, pp. 2635-2640
-
-
Okusawa1
Dinarello2
Yancey3
Endres4
Lawley5
Frank6
Burke7
Gelfand8
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8
-
-
0010331829
-
Expression and secretion of type β transforming growth factor by activated human macrophages
-
Of outstanding interest, Activated macrophages co-secrete TGF-β and an acid-labile TGF-β modulating protein. TGF-β mRNA levels are constitutive. These findings suggest that TGF-β activity is controlled at post-transcriptional and extracellular levels.
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 6020-6024
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-
Assoian1
Fleurdelys2
Stevenson3
Miller4
Madtes5
Raines6
Ross7
Sporn8
-
10
-
-
0023388439
-
Additive effects of interleukin 1 and tumour necrosis factor-α on the accumulation of the three granulocyte and macrophage colony-stimulating factor mRNAs in human endothelial cells
-
Of interest, IL-1 and TNF-α have additive effects in inducing the slow accumulation of GM-CSF and G-CSF and the more rapid accumulation of M-CSF mRNA in endothelial cells.
-
(1987)
EMBO J
, vol.6
, pp. 2261-2265
-
-
Seelentag1
Mermod2
Montesano3
Vassalli4
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11
-
-
0023404771
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Macrophages specifically regulate the concentration of their own growth factor in the circulation
-
125I-CSF-1 is cleared from the circulation by CSF-1 receptor-mediated endocytosis of macrophages. The number of macrophages regulates the plasma concentration of growth factor for macrophages and therefore provides feedback control of macrophage population expansion.
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 6179-6183
-
-
Bartocci1
Mastrogiannis2
Migliorati3
Stockert4
Wolkoff5
Stanley6
-
12
-
-
0023260103
-
Expression of the macrophage-specific colony-stimulating factor in human monocytes treated with granulocyte-macrophage colony-stimulating factor
-
Of interest, GM-CSF, a product of several inflammatory cell types, including macrophages, stimulates macrophages to produce CSF-1 mRNA and activity.
-
(1987)
Blood
, vol.69
, pp. 1259-1261
-
-
Horiguchi1
Warren2
Kufe3
-
13
-
-
0023221767
-
Expression of the M-CSF (CSF-1) gene by human monocytes
-
Of interest, Monocytes induced by IFN-γ or phorbol esters produce CSF-1 transcripts and bioactivity. This suggests that local immune and inflammatory signals can produce further macrophage autostimulation.
-
(1987)
Blood
, vol.69
, pp. 1409-1413
-
-
Rambaldi1
Young2
Griffin3
-
14
-
-
0023635961
-
Phagocytosis and inflammatory stimuli induce GM-CSF mRNA in macrophages through posttranscriptional regulation
-
Of outstanding interest, Inflammatory, phagocytic, and adherence stimuli induce GM-CSF production by macrophages at a post-transcriptional level. γ-Interferon and glucocorticoids suppress this GM-CSF production.
-
(1987)
Cell
, vol.48
, pp. 671-679
-
-
Thorens1
Mermod2
Vassalli3
-
15
-
-
0023482090
-
Transgenic mice expressing a hemopoietic growth factor gene (GM-CSF) develop accumulations of macrophages, blindness, and a fatal syndrome of tissue damage
-
Of outstanding interest, A GM-CSF expressed in transgenic mice leads to high serum GM-CSF levels and accumulation of activated macrophages in retina, striated muscle, and pleural and peritoneal cavities.
-
(1987)
Cell
, vol.51
, pp. 675-686
-
-
Lang1
metcalf2
Cuthbertson3
Lyons4
Stanley5
Kelso6
Kannourakis7
Williamson8
Klintworth9
Gonda10
Dunn11
-
17
-
-
0023079732
-
Disorders of phagocyte function
-
Of interest, Scholarly review of phagocyte disorders of adherence, chemotaxis, phagocytosis, and killing.
-
(1987)
Annu Rev Immunol
, vol.5
, pp. 127-150
-
-
Rotrosen1
Gallin2
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18
-
-
0023251352
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(Letter to the Editor) The glycoprotein encoded by the X -linked chronic granulomatous disease locus is a component of the neutrophil cytochrome b complex
-
Of interest, An approach to identifying the X-CGD gene product.
-
(1987)
Nature
, vol.327
, pp. 717-720
-
-
Dinauer1
Orkin2
Brown3
Jesaitis4
Parkos5
-
20
-
-
0023577495
-
Defensin-rich dense granules of human neutrophils
-
Of interest, A recently discovered antimicrobial polypeptide is segregated in a large, dense myeloperoxidase-positive subclass of PMN azurophil granules.
-
(1987)
Blood
, vol.70
, pp. 757-765
-
-
Rice1
Ganz2
Kinkade3
Selsted4
Lehrer5
Parmley6
-
21
-
-
0023584494
-
Effect of recombinant tumor necrosis factor on tumoricidal activation of murine macrophages — synergism between tumor necrosis factor and γ-interferon
-
Of interest, Inflammatory and immune activators (TNF-α and IFN-γ) synergistically augment macrophage tumoricidal capability.
-
(1987)
Cancer Res
, vol.47
, pp. 5868-5874
-
-
Hori1
Ehrke2
Mace3
Mihich4
-
22
-
-
0023946936
-
A newly defined property of somatotropin: priming of macrophages for production of superoxide anion
-
Of interest, Somatotropin and IFN-γ are equally efficacious in the priming of macrophage superoxide anion production. This may reflect an endocrine effect on killing and inflammation, but somatotropin is thought to be another leukocyte secretory product.
-
(1988)
Science
, vol.239
, pp. 769-771
-
-
Edwards1
Ghiasuddin2
Schepper3
Yunger4
Kelley5
-
23
-
-
0023613504
-
Human alveolar macrophages synthesize active complement components C6, C7 and C8 in vitro
-
Of interest, The authors detect C6, C7, C8 and C9 antigens produced by serum-free cultured human macrophages.
-
(1987)
Scand J Immunol
, vol.25
, pp. 567-570
-
-
Pettersen1
Johnson2
Hetland3
-
24
-
-
0023347690
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The basis for the immunoregulatory role of macrophages and other accessory cells
-
Of interest, Important review of the soluble and membrane-bound macrophage products that mediate the afferent arm of the immune response.
-
(1987)
Science
, vol.236
, pp. 551-557
-
-
Unanue1
Allen2
-
27
-
-
0023202438
-
The collagen substrate specificity of human neutrophil collagenase
-
Of interest, The fundamentally different catalytic mechanisms of the PMN collagenase and the secreted collagenase from fibroblasts are compared.
-
(1987)
J Biol Chem
, vol.262
, pp. 10048-10052
-
-
Hasty1
Jeffrey2
Hibbs3
Welgus4
-
28
-
-
0023214640
-
Molecular cloning of human cathepsin G: structural similarity to mast cell and cytotoxic T lymphocyte proteinases
-
Of interest, This paper reports the molecular structure, including a two-amino acid residue propeptide, of this major degradative enzyme from azurophil granules of PMN and monocytes.
-
(1987)
Biochemistry
, vol.26
, pp. 2289-2293
-
-
Salveson1
Farley2
Shuman3
Przybyla4
Reilly5
Travis6
-
29
-
-
0005237832
-
Primary structure of human neutrophil elastase
-
Of interest, This paper reports the primary structure of PMN elastase, a key component of extracellular matrix destruction and bacteriocidal mechanisms.
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 2228-2232
-
-
Sinha1
Watorek2
Karr3
Giles4
Bode5
Travis6
-
30
-
-
0023665299
-
Monocyte procollagenase and tissue inhibitor of metalloproteinases. Identification, characterization, and regulation of secretion
-
Of interest, Macrophages produce collagenase and its inhibitor TIMP simultaneously.
-
(1987)
J Biol Chem
, vol.262
, pp. 15862-15868
-
-
Campbell1
Cury2
Lazarus3
Welgus4
-
31
-
-
0342642931
-
Coordinate regulation of stromelysin and collagenase genes determined with cDNA probes
-
Of interest, Transcripts for the broad-spectrum basement membrane protein-degrading metalloproteinase stromelysin are expressed by stimulated alveolar macrophages.
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 2600-2604
-
-
Frisch1
Clark2
Werb3
-
32
-
-
0023197175
-
Urokinase-type plasminogen activator: proenzyme, receptor, and inhibitors
-
Of interest, An update on the secretion of urokinase, its inhibitor, and the role of its receptor in localizing plasminogen activation in macrophages.
-
(1987)
J Cell Biol
, vol.104
, pp. 801-804
-
-
Blasi1
Vassalli2
Dano3
-
34
-
-
0022501030
-
Transforming growth factor-a: a more potent angiogenic mediator than epidermal growth factor
-
Of interest, A demonstration of the angiogenic potential of TGF-α.
-
(1987)
Science
, vol.232
, pp. 1250-1253
-
-
Schreiber1
Winkler2
Derynck3
-
37
-
-
0023471275
-
(Letter to the Editor) Interleukin-1 regulates synthesis of nerve growth factor in non-neuronal cells of rat sciatic nerve
-
Of interest, In Wallerian nerve regeneration, debriding macrophages induce non-neuronal cells in nerve to transcribe NGF.
-
(1987)
Nature
, vol.330
, pp. 658-659
-
-
Lindholm1
Heumann2
Meyer3
Thoenen4
-
38
-
-
0023213865
-
Macrophages and atherogenesis
-
Of interest, Good review of the evolution of hypotheses about atherogenesis, with a short part dealing with macrophage secretion products implicated in the process.
-
(1987)
Lancet
, vol.2
, pp. 146-147
-
-
Mitchinson1
Ball2
-
39
-
-
0023253668
-
Synthesis and release of chondroitin sulphate and heparan sulphate proteoglycans from mouse macrophages in vitro
-
Of interest, Resident peritoneal macrophages from mouse synthesize and secrete equivalent amounts of chondroitin sulfate and heparan sulfate proteoglycans.
-
(1987)
Glyco J
, vol.4
, pp. 73-84
-
-
Kolset1
-
40
-
-
0022530255
-
Immunoregulatory feedback between interleukin-1 and glucocorticoid hormones
-
Of interest, Demonstration of feedback regulation between IL-1 and its suppressor glucocorticoids.
-
(1987)
Science
, vol.233
, pp. 652-654
-
-
Besedovsky1
del Rey2
Sorkin3
Dinarello4
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