Identification of a translation inhibitory element (TIE) in the 3′ untranslated region of the human interferon-β mRNA

Gene

Volumn 72, Issue 1-2, 1988, Pages 191-200

  Kruys, Véronique I ^a   Wathelet, Marc G ^a   Huez, Georges A ^a  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

Author keywords

inflammatory response; mRNA stability; Recombinant DNA; SP6 RNA transcripts; translational efficiency

Indexed keywords

BETA INTERFERON; MESSENGER RNA; RADIOISOTOPE; RECOMBINANT DNA;

ANIMAL CELL; GENETIC ENGINEERING; HEREDITY; HUMAN; INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; RNA TRANSLATION;

ANIMAL; BASE SEQUENCE; FEMALE; HUMAN; INTERFERON TYPE I; MOLECULAR SEQUENCE DATA; OOCYTES; PLASMIDS; RABBITS; RETICULOCYTES; RNA, MESSENGER; SUPPORT, NON-U.S. GOV'T; TRANSCRIPTION, GENETIC; TRANSLATION, GENETIC; XENOPUS;

EID: 0024271395     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-1119(88)90144-8     Document Type: Article

References (19)

1. Identification of a common nucleotide sequence in the 3' untranslated region of mRNA molecules specifying inflammatory mediators
2. Control of messenger RNA stability
3. Isolation and structure of a human fibroblast interferon gene
4. The effect of capping and polyadenylation on the stability, movement and translation of synthetic messenger RNAs in Xenopus oocytes
5. Use of frog eggs and oocytes for the study of messeger RNA and its translation in living cells
6. Degradation of deadenylated rabbit alpha-globin mRNA in Xenopus oocytes is associated with its translation
7. Translational stability of native and deadenylated rabbit globin mRNA injected into HeLa cells
8. Translational stability of plant viral RNAs microinjected into living cells, influence of a 3'-poly(A) segment
9. The 3' untranslated region of the human interferon-β mRNA has an inhibitory effect on translation
10. Absence of polyadenylate segment in globin messenger RNA accelerates its degradation in Xenopus oocytes
11. Removal of a 67-base-pair sequence in the non-coding region of protooncogene fos converts it to a transforming gene
12. Transcriptional and posttranscriptional regulation of exogenous human β-interferon gene in simian cells defective in interferon synthesis
13. Noncoding 3' sequences of the transferrin receptor gene are required for mRNA regulation by iron
14. Insertion mutagenesis to increase secondary structure within the 5' noncoding region of a eukaryotic mRNA reduces translational efficiency
15. Analysis of interferon mRNA in human fibroblast cells induced to produce interferon
16. Posttranscriptional gene regulation and specific binding of the non-histone protein HMG-I by the 3' untranslated region of bovine interleukin-2 cDNA
17. A conserved AU sequence from the 3' untranslated region of GM-CSF mRNA mediates selective mRNA degradation
18. Control of interferon mRNA levels and interferon yields in butyrate and 5' bromodeoxyuridine-treated Namalwa cells
19. Identification of two distinct regulatory regions adjacent to the human β-interferon gene