Factors Involved in the Pathogenesis of Hypertensive Cardiovascular Hypertrophy: A Review

Drugs

Volumn 35, Issue 5, 1988, Pages 6-26

  Dahlöf, Björn ^a  

^a SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CARDIOMEGALY; HUMAN; HYPERTENSION; PATHOPHYSIOLOGY; REVIEW;

CARDIOMEGALY; HUMAN; HYPERTENSION;

EID: 0024252905     PISSN: 00126667     EISSN: 11791950     Source Type: Journal    
DOI: 10.2165/00003495-198800355-00003     Document Type: Article

References (218)

1. The sympathetic system in hypertension. State-of-the-art review
2. Sympathetic cross-innervation of SHR and genetic controls suggests a trophic influence on vascular muscle membranes
3. Baker G, Zeller N, Weitzner S, Leach JK. Pheochromocytoma without hypertension presenting as cardiomyopathy. American Heart Journal 83: 688-693, 1971
4. Relation of blood pressure with body and plasma electrolytes in Conn’s syndrome
5. Trophic effects of peripheral adrenergic nerves on vascular structure
6. Editorial review. Cardiac aspects of essential hypertension
7. Growth stimulating effect on catecholamines on rat aortic smooth muscle cells in culture
8. Acceleration of catecholamine biosynthesis in sympathetically innervated tissues by angiotensin II-amide
9. Intestinal microvascular adaptation during maturation of spontaneously hypertensive rats
10. Biochemical and mechanical properties of resistance arteries from normotensive and hypertensive rats
11. Tabular view of the morbid appearance in 100 cases connected with albuminous urine. With observations
12. + pump activity in cultures of smooth muscle from rat aorta
13. Peripheral circulation in arterial hypertension
14. Blood pressure and sodium: a personal view
15. Effects of angiotensin II and vasopressin on human smooth muscle cells in vitro.
16. Juxtaglomerular cell hyperplasia and secondary hyperaldosteronism (Bartter’s syndrome), a re-evaluation of the pathophysiology
17. Detection of hypertensive left ventricular hypertrophy
18. Experimental renal insufficiency produced by partial nephrectomy
19. Is insulin the link between hypertension and obesity
20. Left ventricular wall thickness and plasma catecholamines in borderline and stable essential hypertension
21. Effect of intra-arterial insulin on tissue cholesterol and fatty acids in alloxan-diabetic dogs
22. Cardiac status in juvenile borderline hypertension
23. The control of cell division by tension or diffusion
24. The role of antihypertensive pharmacologic treatment in countering adverse pathophysiological profiles: Influence on small arteries
25. Withdrawal of antihypertensive drugs in mild hypertension
26. Pathophysiologic features of hypertension in young men
27. Echocardiographic determination of left ventricular mass in man: anatomic validation of the method
28. Captopril treatment of hypertension increases low but not normal cardiac index
29. Left ventricular hypertrophy and function in high, normal, and low-renin forms of essential hypertension
30. Sensitivity of echocardiography for detection of left ventricular hypertrophy
31. Left ventricular hypertrophy in patients with hypertension: importance of blood pressure response to regularly recurring stress
32. Relation of hemodynamic load to left ventricular hypertrophy and performance in hypertension
33. Whole blood viscosity as a determinant of cardiac hypertrophy in systemic hypertension
34. Left ventricular hypertrophy in hypertension. Prevalence and relationship to pathophysiological variables
35. Relation of renin-angiotensin system activity to left ventricular hypertrophy and function in experimental and human hypertension
36. The insulin receptor is an agedependent integral component of the human erythrocyte membrane
37. Blood pressure as a determinant of cardiac left ventricular muscle mass
38. Adrenaline sensitivity of peripheral blood vessels in human hypertension
39. Enalapril improves systemic and renal hemodynamics and allows regression of left ventricular mass in essential hypertension
40. Circulatory and sympathoadrenal responses to stress in borderline and established hypertension
41. + exchange system
42. A contribution of the study of arteriosclerosis, with special references to its relation to chronic renal disease
43. Stroke volume pulse pressure relationship in borderline hypertension: a possible indicator of decreased arterial compliance
44. Insulin resistance in essential hypertension
45. Step-down treatment of mild systemic hypertension
46. Norepinephrine metabolism in hypertrophied rat hearts
47. Structural, myogenic, humoral and nervous factors controlling peripheral resistance
48. Central neurohormonal mechanisms in spontaneously hypertensive rats compared with human essential hypertension
49. The Fourth Volhard Lecture. Cardiovascular structural adaptation; its role in the initiation and maintenance of primary hypertension
50. Physiological aspects of primary hypertension
51. ‘Stuctural autoregulation’ — the local adaptation of vascular beds to chronic changes in pressure
52. The structural cardiovascular factor in primary hypertension — pressure dependence and genetic reinforcement
53. Adaptive changes in ‘reactivity’ and wall/ lumen ratio in cat blood vessels exposed to prolonged transmural pressure difference
54. Adaptive structural changes of the vascular wall in hypertension and their relation to the control of the peripheral resistance
55. The haemodynamic consequences of regional hypotension in spontaneously hypertensive and normotensive rats
56. Structural vascular factors in the pathogenesis of hypertension
57. Hemodynamics of hypertension
58. Compared myocardial and vascular effects of captopril and dihydralazine during hypertension development in spontaneously hypertensive rats
59. Structural adaptation of the rat left ventricle in response to changes in pressure and volume loads
60. Cardiac dimensions in spontaneously hypertensive rats following different modes of blood pressure reduction by antihypertensive treatment
61. Hemodynamics and other determinants in development of left ventricular hypertrophy
62. Potential mechanisms explaining the risk of left ventricular hypertrophy
63. The pathogenesis of Bartter’s syndrome. Functional and histological studies
64. Histometrical investigations of arteries in reference to arterial hypertension
65. Pheochromocytoma masquerading as a cardiomyopathy
66. Echocardiographic assessment of a normal adult aging population
67. Some aspects of the cardiovascular system in the giraffe
68. Isoproterenol-induced cardiomegaly: Assessment of myocardial protein content, actomyosin ATPase, and heart rate
69. Left ventricular hypertrophy in coronary heart disease
70. Haemodynamic effects of pindolol in essential hypertension with special reference to resistance vessels in the forearm during maximal vasodilation
71. Mechanisms of regulation of the Na/ H exchanger
72. Wall stress and patterns of hypertrophy in the human left ventricle
73. On the pathology of the morbid state commonly called chronic Bright’s disease with contracted kidney
74. Treatment of hypertension with beta-blockers with and without intrinsic sympathomimetic activity
75. Effect of chronic hypertension and sympathetic denervation on wall-lumen ratio of cerebral vessels
76. Characterization of insulin-like growth factor I receptor on human erythrocytes
77. Ventricular volumes and body weight in mammals
78. Forearm vasoconstrictor response to ouabain: studies in patients with mild and moderate essential hypertension
79. Proline and thymidine uptake in rabbit ear artery segments in vitro increased by chronic tangential load
80. Aggressive long-term antihypertensive therapy with pinacidil does not cause regression of cardiovascular hypertrophy in the spontaneously hypertensive rat
81. On certain points in the anatomy of Bright’s disease of the kidney
82. Hemodynamic studies in patients with borderline blood pressure elevation
83. Hemodynamics of prehypertension and hypertension
84. Autonomic nervous cardiovascular regulation in borderline hypertension
85. Abnormalities of plasma volume in borderline hypertension
86. Binding, degradation and biological activity of insulin in vascular smooth muscle cells
87. Role of blood pressure in cardiovascular morbidity and mortality
88. Prevalence and natural history of electrocardiographic left ventricular hypertrophy
89. Left ventricular hypertrophy by electrocardiogram: prevalence, incidence and mortality in the Framingham Study
90. Electrocardiographic left ventricular hypertrophy and risk of coronary heart disease: the Framingham Study
91. Angiotensin and myocardial protein synthesis
92. Effect of angiotensin II on DNA, RNA and protein synthesis
93. Receptors and growth-promoting effects of insulin and insulin-like growth factors on cells from bovine retinal capillaries and aorta
94. What is the value of home blood pressure measurement in patients with mild hypertension?
95. Effect of long-tern nitrendipine therapy on coronary blood flow and left ventricular hypertrophy in renovascular hypertension
96. Morphological and physiological aspects of cardiac atrophy
97. Causal and homeostatic factors in hypertension
98. The role of the heart in causing and maintaining hypertension
99. Pathogenesis of human primary hypertension: a new approach to the identification of casual factors and to therapy
100. Myocardial hypertrophy produced by chronic infusion of subhypertensive dose of norepinephrine in the dog
101. + antiport abolishes growth factor-induced DNA synthesis in fibroblasts. Structure-activity relationships in the amiloride series
102. Vein graft patency and intimai proliferation after aortocoronary bypass: early and long-term angiopathologic correlations
103. Growth hormone stimulating the growth of arterial medial cells in vitro. Absence of effect of insulin
104. Morphometric study of structural changes in the mesenteric blood vessels of spontaneously hypertensive rats
105. A new in vitro system for studying cell response to mechanical stimulation: different effect of cyclic stretching and agitation on smooth muscle cell biosynthesis
106. Heterogeneity of response of peripheral arteries to antihypertensive drugs in essential hypertension: basic effects and functional consequences
107. Editorial review. Slow pressor mechanisms in hypertension: a role for hypertrophy of resistance vessels?
108. Pathology of the heart in acromegaly. Anatomic findings in 27 autopsied patients
109. Left ventricular mass and function before and after antihypertensive treatment
110. Renal and systemic hemodynamics in sustained essential hypertension
111. Adaptive changes of cardiovascular design in spontaneous and renal hypertension. Hemodynamic studies in rats
112. Regression of structural cardiovascular changes after reversal of experimental renal hypertension in rats
113. Cardiovascular design after ‘reversal’ of long-standing renal hypertension in rats
114. Rate and extent of adaptive cardiovascular changes in rats during experimental renal hypertension
115. Diastolic properties of the hypertrophied left ventricule in spontaneously hypertensive rats
116. Regression of structural cardiovascular changes by antihypertensive therapy in sponeously hypertensive rats
117. Spontaneous changes in central hemodynamics in essential hypertension — a 10 year follow-up study
118. Haemodynamics in essential hypertension
119. Left ventricular function in hypertensive and normotensive subjects from a natural population. Abstract
120. Disparate cardiovascular effects of obesity and arterial hypertension
121. Blood pressure and ageing: results of a 15–17] year follow-up study in South Wales
122. Elastic properties of the myocardium: a quantitative approach with physiological and clinical applications
123. Hyperinsulinaemia: a link between hypertension, obesity and glucose intolerance
124. Clinical aspects of secondary hypertension. Acromegaly and hypertension
125. Reduced responses to noradrenaline of isolated digital arteries from hypertensives
126. Editorial review. The fourth Sir George Pickering Memorial Lecture: the structure of the resistance vasculature in essential hypertension
127. Direct evidence that the greater contractility of resistance vessels in spontaneously hypertensive rats is associated with a narrowed lumen, a thickened media, and an increased number of smooth muscle cell layers
128. Evidence for hyperplasia in mesenteric resistance vessels of spontaneously hypertensive rats using a three-dimensional disector
129. Regression of left ventricular hypertrophy from systemic hypertension by enalapril
130. The renin-angiotensin system and hypertensive left ventricular hypertrophy in the rat
131. Role of the reninangiotensin system in blood pressure regulation: The cardiovascular effects of converting enzyme inhibition in normotensive subjects
132. A simplified radioimmunoassay for physiologically active angiotensin peptides [(1–8) octa- and (2–8) hepto-peptides]
133. Quantitative structural changes of the rat thoracic aorta in early spontaneous hypertension. Tissue composition, and hypertrophy and hyperplasia of smooth muscle cells
134. Cardiac sympathetic nerves as the final common pathway in the induction of adaptive cardiac hypertrophy
135. Pressure-independent increases in vascular resistance to hypertension: role of sympathoadrenergic influences
136. Influence of blood pressure on development of aortic medial smooth muscle hypertrophy in spontaneously hypertensive rats
137. Course of blood pressure in mild hypertension after withdrawal of long term antihypertensive treatment
138. Regression of left ventricular hypertrophy and prevention of left ventricular dysfunction by captopril in the spontaneously hypertensive rat
139. Increased arteriolar wall-to-lumen ratio in a normotensive vascular bed in coarctation hypertension
140. Relationship of blood pressure, serum cholesterol, smoking habit, relative weight, and ECG abnormalities to incidence of major coronary events: Final report of the Pooling Project
141. + exchange system: a genetic approach
142. Cytoplasmic pH, a key determinant of growth factor-induced DNA synthesis in quiescent fibroblasts
143. Cardiovascular complications of pheochromocytoma crisis
144. Cellular biology of the renin-angiotensin system
145. The myocardial intracellular renin-angiotensin system
146. Effect of angiotensin II on RNA synthesis by isolated nuclei
147. Renin synthesis by canine aortic smooth muscle cells in culture
148. Cardiac myocytes contain renin. Abstract
149. Reliable estimation of peak left ventricular systolic pressure by M-mode echographic-determined end-diastolic realtive wall thickness; identification of severe valvular aortic stenosis in adult patients
150. Angiotensin II: Rapid localization in nuclei of smooth and cardiac muscle
151. Acceleration of protein biosynthesis by angiotensin correlation with angiotensin’s effect on catecholamine biosynthesis
152. Stallard TJ, et al. Assessment of left-ventricular mass and its response to antihypertensive treatment
153. Regression of cardiac hypertrophy with drug treatment in spontaneously hypertensive rats
154. Echocardiographic dimensions in borderline and sustained hypertension
155. Peripheral large arteries and the response to antihypertensive treatment
156. Effect of converting enzyme inhibitors on hypertensive large arteries in humans
157. Echocardiographic assessment of cardiac anatomy and function in hypertensive patients
158. Pathogenesis of mineralocorticoid hypertension
159. Effects of Ang II and Ang II antagonist, saralasin on cell growth and renin in 3T3 and SV 3T3 cells
160. Protein synthesis and degradation in cardiac stress
161. Replication of smooth muscle cells in vascular disease
162. ACTH dependent hypertension
163. Adaption of canine saphenous veins to grafting. Correlation of contractility and contractile protein content
164. Collagen synthesis in development and reversal of cardiac hypertrophy in spontaneously hypertensive rats
165. Regression of cardiac hypertrophy and influence of β-adrenergic system
166. Cardiac hypertrophy in spontaneously hypertensive rats
167. Cardiac hypertrophy and antihypertensive therapy
168. Cardiac effects of angiotensin antagonists in normotensive rats
169. Effects of converting enzyme inhibitor (SQ 14, 225) on myocardial hypertrophy in spontaneously hypertensive rats
170. Reversal of cardiac hypertrophy in renal hypertensive rats: medical versus surgical therapy
171. A factor that initiates myocardial hypertrophy in hypertension
172. The interrelation of cardiac and vascular wall hypertrophy in arterial hypertension
173. Haemodynamic basis of early modifications of the large arteries in borderline hypertension
174. Postprandial hyperinsulinaemia in patients with mild essential hypertension
175. The hemodynamic importance of structural vascular changes in essential hypertension
176. Effects of blood pressure reduction on the structural vascular abnormality in skin and muscle vascular beds in human essential hypertension
177. Analysis of angiotensin stimulated sodium transport in cultured smooth muscle cells from rat aorta
178. Three red cell sodium transport systems in hypertensive and normotensive Utah adults
179. Relationship between level of blood pressure measured casually and by portable recorder and severity complications in essential hypertension
180. Connective tissue of the hypertrophied heart
181. Changes in saphenous veins used as aortocoronary bypass grafts
182. Relationship of abnormal circulating insulin to atherosclerosis
183. Effect of insulin on the proliferation of cultured primate arterial smooth muscle cells
184. Arterial wall or plasma renin in hypertension?
185. Thyroxine-induced hypertrophy of the rabbit heart. Effect on regional oxygen extraction, flow and oxygen consumption
186. The multifactorial role of catecholamines in hypertensive cardiac hypertrophy
187. Vascular reactivity of normotensive and hypertensive human arteries
188. Phenotype modulation in primary cultures of arterial smooth muscle cells. On the role of platelet-derived growth factor
189. The effect of α-methyldopa on cardiac hypertrophy in SHR
190. Alterations in arterial structure and their relation to syphylis
191. The effects of prolonged β-adrenoceptor blockade on heart weight and cardiac intracellular potentials in rabbits
192. Impaired systemic arterial compliance in borderline hypertension
193. Cardiovascular effects and regional blood flow distribution associated with angiotensin converting enzyme inhibition (captopril) in essential hypertension
194. Relationships between left ventricular mass and clinical, biohumoral and hemodynamic parameters in human hypertension
195. Organ work and organ weight
196. Aspects of the relation between functional and structural cardiovascular factors in primary hypertension: experimental studies in spontaneously hypertensive rats
197. Long-term treatment with antihypertensive drugs in spontaneously hypertensive rats (SHR). Effects on blood pressure, survival rate and cardiovascular design
198. Effects of hypophyseal hormones on cardiac growth and function
199. Blood pressure and metabolic effects of cortisol and deoxycorticosterone in man
200. Coronary blood flow during the development and regression of left ventricular hypertrophy in renovascular hypertensive rats
201. The cardiac hypertrophy process: analyses of factors determining pathological v sphysiological development
202. Dual ionic controls for the activation of protein synthesis at fertilization
203. Effects of hypertension and its reversal on the thoracic aorta of male and female rats
204. Long-term effects of hypertension on the rat aortic wall and their relation to concurrent aging changes
205. Response of the rat aortic media to hypertension. Morphological and chemical studies
206. Reproducibility of left ventricular internal dimensions with M-mode echocardiography: effects of heart size, body position and transducer angulation
207. Effect of antihypertensive therapy on lysine incorporation into vascular protein of the spontaneously hypertensive rat
208. Cardiac hypertrophy in early hypertension
209. Effects of β-receptor blocking agents on cardiovascular structural changes in spontaneous and noradrenaline-induced hypertension in rats
210. Diversity of membrane abnormalities in spontaneous hypertension
211. Humoral trophic influence on cardiovascular structural changes in hypertension
212. Editorial review. Interaction between sympathetic and renin-angiotensin system
213. Micropressureflow relationships in a skeletal muscle of spontaneously hypertensive rats