Synthesis and biological evaluation of new C (4) heterofunctionalized monocyclic β-lactams derived from penicillin G

European Journal of Medicinal Chemistry

Volumn 23, Issue 6, 1988, Pages 561-571

  Marchand Brynaert, Jacqueline ^a   Laub, Ruth ^a   De Meester, Fabien ^b   Frêre, Jean Marie ^b  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^b UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

antibiotic; monocyclic lactam; penem; suicide inhibition; sulfone

Indexed keywords

BETA LACTAMASE; PENICILLIN G DERIVATIVE;

CELL CULTURE; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; INFRARED SPECTROPHOTOMETRY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE;

EID: 0024236143     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/0223-5234(88)90100-6     Document Type: Article

References (60)

1. Penicillin-Sensitive Enzymes in Peptidoglycan Biosynthesis
2. Structure and absolute configuration of thienamycin
3. New synthesis of penems via a reductive cyclization reaction of oxalimides with trialkyl phosphite.
4. Synthesis of optically active penems
5. Monobactams: Ring Activating N-1-Substituents in Monocyclic b-Lactam Antibiotics
6. Recent Advances in the Chemistry of β-Lactam Antibiotics
7. Recent Advances in the Chemistry of β-Lactam Antibiotics
8. Oxidation of some 1,2-seco-penicillins
9. Syntheses based on 1,2-secopenicillins. Part I. Oxidation
10. Recent Advances in the Chemistry of β-Lactam Antibiotics
11. Recent Advances in the Chemistry of β-Lactam Antibiotics
12. 4-Mercapto-2-azetidinone, II1) Darstellung und Reaktionen von 4-Mercapto-2-azetidinonen
13. The chemistry of 4-mercaptoazetidin-2-ones. Part 1. Preparation and properties of (3R,4R)-4-mercapto-3-phenoxyacetamidoazetidin-2-one