Design and release kinetic pattern evaluation of indomethacin microspheres intended for oral administration

Biomaterials

Volumn 9, Issue 6, 1988, Pages 482-488

  Babay, D ^a   Hoffman, A ^a   Benita, S ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

controlled release; ethylcellulose; Eudragit RL microspheres; Indomethacin; microspheres; oral use; poly(ethylene glycol); release kinetics

Indexed keywords

BENZOCAINE; ETHYL CELLULOSE; INDOMETACIN; MACROGOL; MICROSPHERE; POLYACRYLIC ACID; POLYMETHACRYLIC ACID; PROCAINE;

DRUG RELEASE; METHODOLOGY; NONHUMAN; ORAL DRUG ADMINISTRATION; SUSTAINED RELEASE PREPARATION;

ADMINISTRATION, ORAL; CELLULOSE; DELAYED-ACTION PREPARATIONS; INDOMETHACIN; KINETICS; MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; POLYMERS;

EID: 0024230598     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/0142-9612(88)90042-7     Document Type: Article

References (11)

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8. Microcapsules — new applications and characterization
9. Fundamentals of release mechanism interpretation in multiparticulate systems: determination of substrate release from sing le microcapsules and relation between individual and ensemble release kinetics
10. Mechanism of sustained-action medication. Theoretical analysis of rate release of solid drugs dispersed in solid matrices