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1
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0023198457
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Human mononuclear phagocyte molecules and the use of monoclonal antibodies in their detection
-
Of interest, Useful review of human macrophage antigens, with special reference to leukocyte adhesion glycoproteins and antigens analysed in 3rd Leukocyte Antigen Workshop.
-
(1987)
Clin Exp Immunol
, vol.69
, pp. 687-694
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-
Hogg1
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2
-
-
0023636846
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Immunohistochemical characterisation of macrophages in human liver and gastrointestinal tract: expression of CD4, HLA-DR, OKM1, and the mature macrophage marker 25F9 in normal and diseased tissue
-
Of interest, Thorough and well-illustrated report of phenotype of macrophages in human gut and liver, representing large pools of tissue macrophages whose functions are not well defined. CD4 expression interesting in relation to AIDS pathogenesis.
-
(1987)
J Leukocyte Biol
, vol.42
, pp. 474-484
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-
Hume1
Allan2
Hogan3
Doe4
-
3
-
-
0023626471
-
Leucocyte common antigen is present on osteoclasts
-
Of interest, Further evidence that osteoclasts are haematopoiesic in origin, but express unusual phenotype compared with leukocytes.
-
(1987)
J Pathol
, vol.153
, pp. 121-126
-
-
Athanasou1
Quinn2
McGee3
-
4
-
-
0023515528
-
Monoclonal antibody to the murine type 3 complement receptor inhibits adhesion of myelomonocytic cells in vitro and inflammatory cell recruitment in vitro
-
Of outstanding interest, A new approach to preventing inflammatory cell recruitment by exploiting a monoclonal antibody that inhibits complement receptor function in vivo. CR3 plays a key role in adhesion of myelomonocytic cells to inflamed endothelium.
-
(1987)
J Exp Med
, vol.166
, pp. 1685-1701
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-
Rosen1
Gordon2
-
5
-
-
0023185866
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The macrophage response to central and peripheral nerve injury. A possible role for macrophages in regeneration
-
Of interest, Recruitment of monocytes to injured sciatic but not optic nerve may contribute to differential repair in peripheral versus central nervous system.
-
(1987)
J Exp Med
, vol.165
, pp. 1218-1223
-
-
Perry1
Brown2
Gordon3
-
6
-
-
0023201153
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Interleukin 1 induces interleukin 11. Induction of circulating interleukin 1 in rabbits in vlvo and in human mononuclear cells in vitro
-
Of interest, A further contribution from Dinarello's group that has been deeply involved in the study of II-1 effects in rabbit and man.
-
(1987)
J Immunol
, vol.139
, pp. 1902-1910
-
-
Dinarello1
Ikejima2
Warner3
Orencole4
Lonnemann5
Cannon6
Libby7
-
7
-
-
0023041566
-
Tumor necrosis factor as immunomodulator and mediator of monocyte cytotoxicity induced by itself yinterferon and interleukin 1
-
Of interest, One of many ongoing studies exploring the interactions between TNF, macrophages and other cytokines.
-
(1987)
Nature
, pp. 86
-
-
Philip1
Epstein2
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8
-
-
0023622458
-
Two types of mouse helper T cell clone. III. Further differences in lymphokine synthesis between Thl and Th2 clones revealed by RNA hybridization, functionally monospecific bioassays, and monoclonal antibodies
-
Of interest, In this study the authors have demonstrated that T helper cell clones can be classified according to their ability to produce different lymphokines and thus account for differences in immune functions. An important advance.
-
(1987)
J Exp Med
, vol.166
, pp. 1229-1244
-
-
Cherwinski1
Schumacher2
Brown3
Mosmann4
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9
-
-
0023229234
-
Independent regulation of tumor necrosis factor and lymphotoxin production by human peripheral blood lymphocytes
-
Of interest, The cytotoxic and immunomodulating products of lymphocytes and monocytes are compared in this study.
-
(1987)
J Exp Med
, vol.165
, pp. 1581-1594
-
-
Cuturi1
Murphy2
Costa-Giomi3
Weinmann4
Perussia5
Trinchieri6
-
10
-
-
0023609324
-
Tumor necrosis factor/cachectin stimulates peritoneal macrophages, polymorphonuclear neutrophils, and vascular endothelial cells to synthesize and release platelet-activating factor
-
Of interest, The increasingly complex network of interactions between monokines and other cells involved in inflammation and repair. Evidence for a link between 2 key players, TNF/cachectin and PAF.
-
(1987)
J Exp Med
, vol.166
, pp. 1390-1404
-
-
Camussi1
Bussolino2
Salvidio3
Baglioni4
-
11
-
-
0023091309
-
Tumor necrosis factor is chemotactic for monocytes and polymorphonuclear leukocytes
-
Of interest, Monokines can induce recruitment of myelomonocytic cells and thus amplify an inflammatory response.
-
(1987)
J Immunol
, vol.138
, pp. 1459
-
-
Ming1
Bessani2
Mantovani3
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12
-
-
0345658600
-
Expression of haemopoietic growth factor genes in murine T lymphocytes
-
Of interest, T cell-derived growth factors play a key role in regulating haematopoietic cell production in cell-mediated immunity. A useful review of how these genes are regulated in T cells.
-
(1987)
Lymphokines
, vol.13
, pp. 209-238
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-
Kelso1
Gough2
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13
-
-
0023833863
-
Interleukin 4 induces cultured monocytes/macrophages to form giant multinucleated cells
-
Of interest, A “B cell” stimulating factor which induces fusion of macrophages, a common process observed in vitro and in vivo.
-
(1988)
J Exp Med
, vol.167
, pp. 598-611
-
-
McInnes1
Rennick2
-
14
-
-
0023254848
-
Evidence for effects of interleukin 4 (B cell stimulatory factor 1) on macrophages. Enhancement of antigen presenting ability of bone marrow-derived macrophages
-
Of interest, A B cell stimulating factor which alters macrophage phenotype.
-
(1987)
J Immunol
, vol.138
, pp. 4275-4279
-
-
Zlotnik1
Fischer2
Roehns3
Zipori4
-
15
-
-
0023272603
-
B cell stimulatory factor-1 (IL-4) activates macrophages for increased tumoricidal activity and expression of la antigens
-
Of interest, IL-4 may be one of the long searched for non-γ interferon macrophage activating factors.
-
(1987)
J Immunol
, vol.139
, pp. 135-141
-
-
Crawford1
Finbloom2
Ohara3
Paul4
Meltzer5
-
16
-
-
0023919271
-
Human recombinant interleukin 4 induces FCRE/CD23 on normal human monocytes
-
Of interest, Receptor antigen modulation by 11-4, relevant to lymphokines which regulate different immune responses.
-
(1988)
J Exp Med
, vol.167
, pp. 1406-1417
-
-
Vercelli1
Jabara2
Lee3
Woodland4
Gha5
Leung6
-
17
-
-
0023506438
-
Hemopoietic growth factors and their interactions with specific receptors
-
Of interest, A succinct review of the specific plasma membrane receptors which underlie responses of haematopoietic cells to purified growth factors.
-
(1987)
Journal of Cellular Physiology
, pp. 9-14
-
-
Nicola1
-
18
-
-
0023404771
-
Macrophages specifically regulate the concentration of their own growth factor in the circulation
-
Of interest, The regulation of circulating growth factor levels involves mature cells (tissue macrophages) as well as precursors. An attempt to link peripheral cell activities and monocytopoiesis.
-
(1987)
Proc Natl Acad So USA
, vol.84
, pp. 6179-6183
-
-
Bartocci1
Mastrogiannis2
Migliorati3
Stockert4
Wolkoff5
Stanley6
-
19
-
-
0022916121
-
Cytokines and their receptors
-
Of interest, An even more succinct review of an active field.
-
(1987)
Immunology Today
, vol.7
, pp. 320-321
-
-
Watson1
-
20
-
-
0023229627
-
Characterization of human and mouse granulocyte-macrophagecolony-stimulating factors derived from escbericbia cola
-
Of interest, Although no longer a novelty, the isolation and production of re-combinant colony-stimulating factors has transformed experimental haematopoiesis.
-
(1987)
Biochem J
, vol.247
, pp. 195-199
-
-
Schrimsher1
Rose2
Simona3
Wingfield4
-
21
-
-
0023552425
-
The expression of a γinterferon-induced protein (IP-10) in delayed immune responses in human skin
-
Of interest, One of a series of studies from Cohn's laboratory, leaders in the field, in which a newly developed research observation (a novel protein induced by interferon in cell culture) is used to study cell activation during cell mediated immune responses in human skin.
-
(1987)
J Exp Med
, vol.166
, pp. 1098-1108
-
-
Kaplan1
Luster2
Hancock3
Cohn4
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23
-
-
2342496439
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Transforming growth factor type βinduces monocyte chemotaxis and growth factor production
-
Of interest, TGF-β, made by macrophages and other cells, can recruit monocytes to a site of injury by stimulating chemotaxis and production of growth factors. A collaboration which merges the research of 2 groups.
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 5788-5792
-
-
Wahl1
Hunt2
Wakefield3
McCartney-Francis4
Wahl5
Roberts6
Sporn7
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24
-
-
0023191301
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−245
-
Of outstanding interest, Identification of the gene involved in a rare, but instructive form of an inherited leukocyte deficit in respiratory burst and microbial killing. Segal's group identified an unusual cytochrome in the plasma membrane of chronic granulomatous disease leukocytes and followed a classic strategy of protein purification to the cDNA. Orkin's group [7] used a genetic strategy that (almost) comes to the same answer.
-
(1987)
Nature
, vol.327
, pp. 720-721
-
-
Teahan1
Rows2
Parker3
Totty4
Segal5
-
25
-
-
0023251352
-
(Letter to the editor) The glycoprotein encoded by the X-linked chronic granulomatous disease locus is a component of the neutrophil cytochrome b complex
-
Of outstanding interest, Identification of the gene involved in a rare, but instructive form of an inherited leukocyte deficit in respiratory burst and microbial killing. Segal's group identified an unusual cytochrome in the plasma membrane of chronic granulomatous disease leukocytes and followed a classic strategy of protein purification to the cDNA. Orkin's group [7] used a genetic strategy that (almost) comes to the same answer.
-
(1987)
Nature
, vol.327
, pp. 717-720
-
-
Dinauer1
Orkin2
Brown3
Jesaitis4
Parkos5
-
26
-
-
0023120503
-
In vitro and in vivo activation of human mononuclear phagocytes by interferon-γ: studies with normal and AIDS monocytes
-
Of interest, Part of the profound immunosuppression and susceptibility to opportunistic infection in late AIDS is due to secondary failure of macrophage activation by interferon γ. This study shows that monocytes from AIDS patients are normally responsive to recombinant interferon γ when this is supplied in culture and their activity in vivo can be transiently enhanced by systemic administration.
-
(1987)
J Immunol
, vol.138
, pp. 2457-2462
-
-
Murray1
Scavuzzo2
Jacobs3
Schindler4
Roberts5
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27
-
-
0023925586
-
Analysis of the nonfunctional respiratory burst in murine Kupffer cells
-
Of interest, A study of a mechanism of an interesting phenomenon relating to Kupffer cell function.
-
(1987)
Journal of Experimental Medicine
, vol.167
, pp. 1154-1170
-
-
Ding1
Nathan2
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28
-
-
0023513913
-
(Letter to the Editor) Apparent role of the macrophage growth factor, CSF-1, in placental development
-
Of interest, Although highly restricted to macrophages which bear receptors for this specific growth and differentiation-inducing glycoprotein, CSF-1 may play a role in other tissues and not necessarily through their macrophage population. A study from the Stanley group that has done much to characterise the CSF-1 molecule and its effects on macrophages.
-
(1987)
Nature
, vol.330
, pp. 484-486
-
-
Pollard1
Bartocci2
Arceci3
Orlofsky4
Ladner5
Stanley6
-
29
-
-
0023278996
-
Recombinant human granulocyte colony-stimulat ing factor. Effects of hematopolesis in normal and cyclophosphamide-treated primates
-
Of interest, The availability of pure, specific CSF in unlimited amounts has made it possible to demonstrate biological activity within primates and mouse. These studies illustrate the potential value of GM-CSF products in clinical patients with myeloid dysfunction here and in [30].
-
(1987)
J Exp Med
, vol.165
, pp. 941-948
-
-
Welte1
Bonilla2
Gillio3
Boone4
Potter5
Gabrilove6
Moors7
O'Reuly8
Souza9
-
30
-
-
0023201009
-
Recombinant human granulocyte colony-stimulating factor repairs the abnormalities of neutrophlls in patients with myelodysplastic syndromes and chronic myelogenous leukemia
-
Of interest, The availability of pure, specific CSF in unlimited amounts has made it possible to demonstrate biological activity within primates and mouse. These studies illustrate the potential value of GM-CSF products in clinical patients with myeloid dysfunction here and in [30].
-
(1987)
Blood
, vol.70
, pp. 404-411
-
-
Yuo1
Kitagawa2
Okabe3
Urabe4
Komatsu5
Itoh6
Takaku7
-
31
-
-
0023482090
-
Transgenic mice expressing a hemopoietic growth factor gene (GM-CSF) develop accumulations of macrophages, blindness, and a fatal syndrome of tissue damage
-
Of outstanding interest, A fascinating study which shows that massive production of GM-CSF in mice by genetic manipulation results in strange new forms of pathology, perhaps by overproduction of activated macrophages.
-
(1987)
Cell
, vol.51
, pp. 675-686
-
-
Lang1
Metcalf2
Cuthbertson3
Lyons4
Stanley5
Kelso6
Kannourakis7
Williamson8
Klintworth9
Gonda10
Dunn11
-
32
-
-
0023147156
-
Secretory production of macrophages
-
Of outstanding interest, A useful compilation of the extensive secretory repertoire of macrophages.
-
(1987)
J Clin Invest
, vol.79
, pp. 319-326
-
-
Nathan1
-
33
-
-
0023241480
-
Quantitative immunocytochemical characterization of mononuclear phagocytes. 2. Monocytes and tissue macrophages
-
Of interest, An attempt to standardize, in cell culture, the measurement of antigens by otherwise qualitative immunocytochemistry.
-
(1987)
Immunology
, vol.62
, pp. 171-176
-
-
Nibbering1
Leijh2
Vanfurth3
-
34
-
-
0023280614
-
Human spleen contains phenotypic subsets of macrophages and dendritic cells that occupy discrete microanatomic locations
-
Of interest, A careful, detailed analysis of the complex phenotypes and heterogeneity of macrophages and other dendritic-type accessory cells in human spleen.
-
(1987)
Am J Patbol
, vol.128
, pp. 505-520
-
-
Buckley1
Smith2
Braverman3
Dickson4
-
35
-
-
0023269530
-
Isolation of hepatocyte stimulating factor from human monocytes
-
Of interest, A further example of a long-pursued study by Fuller's group that monocyte products regulate hepatocyte acute phase proteins, as part of the host response to injury.
-
(1987)
Biochern Biophys Res Commun
, vol.144
, pp. 1003-1009
-
-
Fuller1
Bunzel2
Woloski3
Nham4
-
36
-
-
0023638337
-
Self-renewal of pulmonary alveolar macrophages: evidence from radiation chimera studies
-
Of interest, Alveolar macrophages differ from other resident tissue macrophages in their ability to replicate. This group has documented the unusuttl proliferative properties of alveolar macrophages over many years.
-
(1987)
J Leukocyte Biol
, vol.42
, pp. 443-446
-
-
Tarling1
Lin2
Hsu3
-
37
-
-
0023182319
-
Human epidermal Langerhans cells internalize by receptormediated endocytosis T6 (CD1 ‘NAl/34’) surface antigen. Birbeck granules are involved in the intracellular traffic of the T6 antigen
-
Of interest, Epidermal Langerhans cells play an important role in presenting foreign antigens. Their characteristic Birbeck granules may be evidence of unusual endocytic activities which contribute to protein processing.
-
(1987)
J Invest Detrnatol
, vol.89
, pp. 172-177
-
-
Hanau1
Fabre2
Schmit3
Stampf4
Garaud5
Bieber6
Grosshans7
Benezra8
Cazenave9
-
38
-
-
0023553325
-
Modulation of CD4 antigens on macrophages and microglia in rat brain
-
Of outstanding interest, Macrophages are the only cells normally present in brain which express CD4, the entry receptor for human immunodeficiency virus (HIV). This study in rat explores the control of CD4 on monocytes, macrophages and microglia, to cast light on receptor modulation and its possible role in the pathogenesis of HIV encephalopathy. An unexpected discovery is that the blood brain barrier influences CD4 expression by microglia and that circumventricular cells, which are in contact with plasma products of the sytemic circulation, express higher levels of CD4 than microglia within the blood brain barrier.
-
(1987)
J Exp Med
, vol.166
, pp. 1138-1143
-
-
Perry1
Gordon2
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