Locally applied estrogens potentiate glutamate-evoked excitation of cerebellar Purkinje cells

Brain Research

Volumn 475, Issue 2, 1988, Pages 272-282

  Smith, Sheryl S ^a   Waterhouse, Barry D ^a   Woodward, Donald J ^b  

^a DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Cerebellar Purkinje cell; Estrogen; Glutamate; Neuromodulation; Pressure ejection

Indexed keywords

ESTRADIOL; ESTRADIOL BENZOATE; ESTRONE; GLUTAMIC ACID; PROGESTERONE; RADIOISOTOPE;

ACTION POTENTIAL; ANIMAL EXPERIMENT; CEREBELLUM; FEMALE; IONTOPHORESIS; NERVE EXCITABILITY; NONHUMAN; PRIORITY JOURNAL; PURKINJE CELL; RAT;

ACTION POTENTIALS; ANIMAL; ESTRADIOL; ESTROGENS; ESTRONE; FEMALE; GLUTAMATES; GLUTAMIC ACID; OVARIECTOMY; PURKINJE CELLS; RATS; RATS, INBRED STRAINS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0024215765     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-8993(88)90615-4     Document Type: Article

References (44)

1. Biophysical aspects of the mechanism of action of steroid hormones
2. The first proestrus in the female rat, Circulating steroid levels preceeding and accompanying the preovulatory LH surge
3. Changes in physiological, EEG and psychological parameters in women during the spontaneous menstrual cycle and following oral contraceptives
4. Sex differences and estrous cycle variations in amphetamine-elicited rotational behavior
5. The influence of estrous cycle and intrastriatal estradiol on sensorimotor performance in the female rat
6. Hormone-induced enlargement of receptive fields in trigeminal mechanoreceptive neurons. I. Time course, hormone, sex and modality specificity
7. Stimulatory effect of ß-estradiol treatment on GABA-degradative enzymes within rat cerebellar cortex
8. Alterations in basal firing rate and autoreceptor sensitivity of dopamine neurons in the substantia nigra following acute and extended exposure to estrogen
9. 3H]17ß-oestradiol metabolites in female rat tissues, during long-term intravenous infusions
10. Effect of estrogen on the electrical activity of identified and unidentified hypothalamic units
11. An improved constant current source for microiontophoretic drug application studies
12. Sensory changes during the menstrual cycle
13. Studies in vigor
14. An analysis of the activities of 3 key enzymes concerned with interconversion of α-ketoglutarate and glutamate, correlations with free glutamate levels in 20 specific regions of the nervous system
15. Comparative effects of estradiol stereoisomers on Pimozide-induced catalepsy, locomotor activity and body-weight in the rat
16. Estradiol application to one striatum produces postural deviation to systemic apomorphine
17. The effects of microelectrophoretically applied estrogen, cortisol and acetylcholine on medial preoptic septal unit activity throughout the estrous cycle of the female rat
18. Effects of estrogen treatment on the size of receptive field and response threshold of pudendal nerve in the female rat
19. Estrogen effects on neuronal responsiveness to electrical and neurotransmitter stimulation, an in vitro study on the ventromedial nucleus of the hypothalamus
20. Effects of steroids on cerebral electrical activity
21. A pressure system for intracellular and extracellular ejections of picoliter volumes
22. Early estrogen action, Concomitant stimulation with 2 minutes of nuclear RNA synthesis and uptake of RNA precursor by the uterus
23. Interactions of norepinephrine with Purkinje cell responses to putative amino acid neurotransmitters applied by microiontophoresis
24. Variations in pedometer activity during the menstrual cycle
25. Effect of estradiol on the amygdala and ventromedial hypothalamic neurons
26. Effects of in vitro progesterone and estradiol-17ß on the contractile and electrical responses in rat myometrium
27. Physical and physiological characteristics of micropressure ejection of drugs from multibarreled pipettes
28. Estrone sulfatase activity in the human brain and estrone sulfate levels in the normal menstrual cycle
29. Structural requirements for maximal inhibitory allosteric effect of estrogens and estrogen analogues on glutamate dehydrogenase
30. Pressure ejection of drugs on single neurons in vivo, Technical considerations and application to the study of estradiol effects
31. Influence of gonadal hormones in social, sexual, emergence, and open field behavior in the rat
32. Estrogen action at endometrial membranes, Alterations in luminal surface detectable within seconds
33. Progesterone alters GABA and glutamate responsiveness, A possible mechanism for its anxiolytic action
34. Locally applied progesterone metabolites alter neuronal responsiveness in the cerebellum
35. Sex steroid effects on extrahypothalamic CNS. I. Estrogen augments neuronal responsiveness to iontophoretically applied glutamate in the cerebellum
36. Sex steroid effects on extrahypothalamic CNS II. Progesterone, alone and in combination with estrogen, modulates cerebellar responses to amino acid neurotransmitters
37. Induction of sexual receptivity in ovariectomized rats by pulse administration of oestradiol-17ß
38. Steroid hormones stabilize liposomal membrane from alteration by tubulin
39. Mechanisms of hormone action. Parallels in receptor-mediated signal propagation for steroid and peptide effectors
40. Gonadal steroids, Effects on excitability of hippocampal and pyramidal cells
41. Steroid binding to synaptic plasma membrane. Differential binding of glucocorticoids, and gonadal steroids
42. The gonad-brain relationship. Effects of female sex hormones on electroshock convulsions in the rat
43. Behavioral changes associated with the menstrual cycle An experimental investigation