Hydrixyl radical generation by the tetracycline antibiotics with free radical damage to DNA, lipids and carbohydrate in the presence of iron and copper salts

Free Radical Biology and Medicine

Volumn 5, Issue 5-6, 1988, Pages 341-348

  Quinlan, Gregory J ^a   Gutteridge, John M C ^a  

^a NATIONAL INSTITUTE FOR BIOLOGICAL STANDARDS AND CONTROL   (United Kingdom)

Author keywords

Deoxyribose degradation; Desferrioxamine; DNA damage; Fenton chemistry; Free radical; Hydroxyl radicals; Lipid peroxidation; Superoxide dismutase; Tetracycline antibiotics

Indexed keywords

CHLORTETRACYCLINE; COPPER; DEOXYRIBOSE; DOXYCYCLINE; FREE RADICAL; HYDROXYL RADICAL; IRON; OXYTETRACYCLINE; TETRACYCLINE;

DNA DAMAGE; GENETIC ENGINEERING; LIPID PEROXIDATION; NONHUMAN;

ANIMAL; CARBOHYDRATES; CATTLE; COPPER; DEOXYRIBOSE; DNA DAMAGE; FERRIC COMPOUNDS; FREE RADICALS; HYDROXIDES; HYDROXYL RADICAL; LIPID PEROXIDATION; LIPIDS; LIPOSOMES; MANNITOL; TETRACYCLINES; THIOUREA;

EID: 0024210266     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/0891-5849(88)90106-2     Document Type: Article

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