The effects of oxygen radical - mediated pulmonary endothelial damage on cancer metastasis

Molecular and Cellular Biochemistry

Volumn 84, Issue 2, 1988, Pages 189-198

  Orr, F W ^a   Adamson, I Y R ^b   Warner, D ^a   Leroyer, V ^b   Werner, L ^b   Shaughnessy, S ^a   Young, L ^b  

^a MCMASTER UNIVERSITY   (Canada)

^b UNIVERSITY OF MANITOBA   (Canada)

Author keywords

endothelium; free radicals; metastasis

Indexed keywords

BLEOMYCIN; FREE RADICAL;

ANIMAL CELL; ANIMAL EXPERIMENT; INTRAVENOUS DRUG ADMINISTRATION; LUNG ENDOTHELIUM; METASTASIS; MOUSE; NONHUMAN; TISSUE INJURY; ULTRASTRUCTURE;

ANIMAL; CAPILLARIES; COBRA VENOMS; ENDOTHELIUM; FREE RADICALS; LUMINESCENCE; LUNG; MICROSCOPY, ELECTRON; N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE; NEOPLASM METASTASIS; OXYGEN; RATS; RATS, INBRED STRAINS; SUPPORT, NON-U.S. GOV'T;

EID: 0024209445     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/BF00421054     Document Type: Article

References (49)

1. Cancer Metastasis: experimental approaches, theoretical concepts, and impacts for treatment strategies
2. The biology of cancer metastasis and implications for therapy
3. Tumor invasion and metastases — Role of the extracellular matrix: Rhoads memorial award lecture
4. Beta 1–6 branching of ASN-linked oligosaccharides is directly associated with metastasis
5. Metastatic tumor cell attachment and invasion assay utilizing vascular endothelial cell monolayers
6. Specificity of adhesion between tumor cells and capillary endothelium: an in vitro correlate of preferential metastasis in vivo
7. Interleukin-1 acts on cultured human vascular endothelium to increase the adhesion of polymorphonuclear leukocytes, monocytes, and related leukocyte cell lines
8. Role of collagenases in tumor cell invasion
9. Fibronectin contains distinct adhesion and motility-promoting domains for metastatic melanoma cells
10. Isolation of a subunit of laminin and its role in molecular structure and tumor cell attachment
11. Metastatic tumor cells adhere preferentially to the extracellular matrix underlying vascular endothelial cells
12. Tumor cell attachment to the vascular endothelium and subsequent degradation of the subendothelial extracellular matrix
13. Effect of natural protease inhibitors and a chemoattractant on tumor cell invasion in vitro
14. Arrest and extravasation of B16 amelanotic melanoma in murine lungs. A light and electron microscopic study
15. Enhancement of pulmonary metastases by X-irradiation in rats bearing mammary cancer
16. Artificial metastases and decrease of fibrinolysis in the nude mouse lung after hemithoracic irradiation
17. Enhancement of artificial lung metastases in mice caused by cyclophosphamide. I. Participation of impairment of host antitumor resistance
18. Metastasis of a transplantable mammary tumour in rats treated with cyclophosphamide and/or irradiation
19. Amplified pulmonary metastases of a rat rhabdomyosarcoma in respone to nitrosourea treatment
20. Enhancement by cytotoxic agents of artificial pulmonary metastasis
21. DNA strand scission by activated bleomycin group antibiotics
22. Singlet oxygen production by bleomycin. A comparison with heme-containing compounds
23. Effects of dimethyl sulfoxide (DMSO) on bleomycin-induced pulmonary fibrosis
24. The pathogenesis of bleomycin induced pulmonary fibrosis in mice
25. Bleomycin-induced injury and metaplasia of alveolar Type 2 cells
26. Promotion of pulmonary metastasis by bleomycin-induced endothelial injury
27. Pulmonary oxygen toxicity
28. Endothelial regeneration as a marker of the differential vascular responses in oxygen-induced pulmonary edema
29. Tumor metastasis after hyperoxic injury and repair of the pulmonary endothelium
30. Quantification of metastasic tumor growth in bleomycin-injured lungs
31. Drug-induced pulmonary fibrosis
32. Effects of injury and repair of the pulmonary endothelium on lung metastasis after bleomycin
33. Intravascular activation of complement and acute lung injury
34. Complement and neutrophil-mediated injury of perfused rat lungs
35. The role of the polymorphonuclear leukocyte in the pathogenesis of the adult respiratory distress syndrome
36. Effects of neutrophil-mediated pulmonary endothelial injury on the localization and metastasis of circulating Walker carcinosarcoma cells
37. Generation of a complement-derived chemotactic factor for tumor cells in experimentally induced peritoneal exudates and its effect on the local metastasis of circulating tumor cells
38. Studies on the mechanisms of invasion in cancer. II. In Vivo effects of a factor chemotactic for cancer cells
39. Binding of formyl peptides to Walker 256 carcinosarcoma cells and their chemotactic response
40. Phorbol ester binding to chemotactically responding and non-responding Walker 256 carcinosarcoma cells
41. Relationships between chemotaxis, chemotactic modulators and cyclic nucleotide levels in tumor cells
42. Phorbot myristae acetate-induced adherence of Walker 256 carcinosarcoma cells
43. Size increase induced in Walker ascites cells by chemotactic factors
44. Chemiluminescence and oxygen radical generation by Walker carcinosarcoma cells after chemotactic stimulation
45. Oxidative autoactivation of latent collagenase by human neutrophils
46. Degradation of human glomerular basement membrane by stimulated neutrophils. Activation of a metalloproteinase(s) by reactive oxygen metabolites
47. Myeloperoxidase-catalyzed inactivation of alpha 1-protease inhibitor by human neutrophils