Syndrome of Idiopathic Hyperammonemia after High-Dose Chemotherapy: Review of Nine Cases

The American Journal of Medicine

Volumn 85, Issue 5, 1988, Pages 662-667

  Mitchell, R Brian ^c   Wagner, John E ^c   Karp, Judith E ^c   Watson, Alan J ^c   Brusilow, Saul W ^c   Przepiorka, Donna ^a   Saral, Rein ^a   Storb, Rainer ^b   Santos, W ^b   Burke, Philip J ^b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

AMMONIA; AMSACRINE; ANTINEOPLASTIC AGENT; BUSULFAN; CYCLOPHOSPHAMIDE; CYCLOSPORIN; CYTARABINE; DAUNORUBICIN; ETOPOSIDE; IMMUNOSUPPRESSIVE AGENT; METHOTREXATE; VINCRISTINE;

BONE MARROW TRANSPLANTATION; CLINICAL ARTICLE; FEMALE; FOLLOW UP; HUMAN; HYPERAMMONEMIA; LEUKOPENIA; LYMPHATIC LEUKEMIA; MALE; MYELOID LEUKEMIA; PATHOPHYSIOLOGY; PRIORITY JOURNAL;

ADOLESCENT; ADULT; AMMONIA; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BRAIN DISEASES; FEMALE; HUMAN; LEUKEMIA; MALE; MENTAL DISORDERS; MIDDLE AGE; NEUTROPENIA; SUPPORT, U.S. GOV'T, P.H.S.; SYNDROME;

EID: 0024203002     PISSN: 00029343     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9343(88)80239-0     Document Type: Article

References (40)

1. Transient idiopathic hyperammonemia in adults
2. Hyperammonaemic encephalopathy in chronic myelomonocytic leukaemia (letter)
3. Two-cycle timed-sequential chemotherapy for adult acute nonlymphocytic leukemia
4. Autologous bone marrow transplantation in patients with acute nonlymphocytic leukemia: a phase II clinical study of ex vivo marrow treatment with 4-hydroperoxycyclophosphamide
5. Bone marrow transplantation in leukemia: current status
6. Thalidomide therapy of chronic graftversus-host disease (abstr)
7. A kinetic determination of ammonia in plasma
8. Treatment of inborn errors of urea synthesis: activation of alternative pathways of waste nitrogen synthesis and excretion
9. Reye's syndrome: current concepts
10. Cerebral edema: a major complication of massive hepatic necrosis
11. Urea cycle disorders and other hereditary hyperammonemic syndromes
12. Acute hyperammonemia in the young primate: physiologic and neuropathologic correlates
13. Hepatic encephalopathy (letter)
14. 13N-labeled ammonia in rat brain
15. Glutamine synthetase: glial localization in brain
16. Cerebrospinal fluid glutamine as a measure of hepatic encephalopathy
17. Ammonia metabolism in the CNS
18. Hepatic encephalopathy
19. Cerebrovascular effects of ammonia In vitro
20. Effect of elevated serum ammonia on intracranial pressure
21. Blood/brain barrier and brain oedema in ammonia intoxication
22. Non-ionic diffusion and excretion of weak acids and bases
23. The role of pH gradient in the distribution of ammonia between blood and cerebrospinal fluid brain and muscle
24. Acid-base equilibrium between blood and cerebrospinal fluid
25. Intracellular pH of brain: alterations in acute respiratory acidosis and alkalosis
26. The intracellular pH in the brain in acute and sustained hypercapnia
27. Effect of alterations in blood pH on distribution of ammonia from blood to cerebrospinal fluid in patients in hepatic coma
28. The distribution of ammonia between extracellular and intracellular compartments of the rat brain
29. Pathophysiology and management of raised intracranial pressure
30. 2 and cerebral hemodynamics
31. The pressure-volume curve of the cerebrospinal fluid space in dogs
32. Effects of increased cerebrospinal fluid pressure on the blood flow and on the energy metabolism of the brain
33. Cerebral protection: pathophysiology and treatment of increased intracranial pressure
34. Treatment of episodic hyperammonemia in children with inborn errors of urea synthesis
35. Waste nitrogen excretion via amino acid acylation: benzoate and phenylacetate in lysinuric protein intolerance
36. Studies in the synthesis of hippuric acid in the animal organism
37. Synthesis of glycocoll and glutamine in the human organism
38. Mycoplasmas
39. Electroencephalogram changes secondary to asparaginase
40. Hyperammonemia with valproic acid therapy