Apparent involvement of phospholipase A2, but not protein kinase C, in the pro-oxidative interactions of clofazimine with human phagocytes

Biochemical Pharmacology

Volumn 37, Issue 24, 1988, Pages 4635-4641

  Anderson, Ronald ^a   Beyers, Albertus D ^b   Savage, Joanne E ^a   Nel, Andre E ^b  

^a Institute for Pathology   (South Africa)

^b UNIVERSITY OF STELLENBOSCH   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; 4 BROMOPHENACYL BROMIDE; ARACHIDONIC ACID; CALCIUM IONOPHORE; CLOFAZIMINE; FORMYLMETHIONYLLEUCYLPHENYLALANINE; PHORBOL 12 ACETATE 13 MYRISTATE; PHOSPHOLIPASE A2; PROTEIN KINASE C; RADIOISOTOPE; SUPEROXIDE; ZYMOSAN; 4-BROMOPHENACYL BROMIDE; ACETOPHENONE DERIVATIVE; ARACHIDONIC ACID DERIVATIVE; ISOQUINOLINE DERIVATIVE; N FORMYLMETHIONINE LEUCYL PHENYLALANINE; PHOSPHOLIPASE; PHOSPHOLIPASE A; PIPERAZINE DERIVATIVE;

DRUG CONCENTRATION; HUMAN; HUMAN CELL; NEUTROPHIL; PRIORITY JOURNAL; ARTICLE; BLOOD; DOSE RESPONSE; DRUG EFFECT; IN VITRO STUDY; METABOLISM;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; ACETOPHENONES; ARACHIDONIC ACID; ARACHIDONIC ACIDS; CLOFAZIMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMAN; IN VITRO; ISOQUINOLINES; N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE; NEUTROPHILS; PHOSPHOLIPASES; PHOSPHOLIPASES A; PIPERAZINES; PROTEIN KINASE C; SUPEROXIDES;

EID: 0024165314     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(88)90332-2     Document Type: Article

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