Amnesic effect of the novel anticonvulsant MK-801

Pharmacology, Biochemistry and Behavior

Volumn 30, Issue 1, 1988, Pages 205-207

  Benvenga, Mark J ^a   Spaulding, Theodore C ^a  

^a Pharmacology Group Anaquest BOC Health Care 100 Mountain Avenue Murray Hill NJ 07974 USA ^*  (United States)

Author keywords

Amnesia; MK 801; Phencyclidine; Scopolamine

Indexed keywords

DIZOCILPINE; SCOPOLAMINE;

AMNESIA; ANIMAL EXPERIMENT; INTRAVENOUS DRUG ADMINISTRATION; MALE; MEMORY; MOUSE; NONHUMAN; PASSIVE AVOIDANCE; PRELIMINARY COMMUNICATION; PRIORITY JOURNAL;

ANIMAL; ANTICONVULSANTS; DIBENZOCYCLOHEPTENES; DIZOCILPINE MALEATE; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; MEMORY; MICE; REACTION TIME; SCOPOLAMINE;

EID: 0024161251     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/0091-3057(88)90445-5     Document Type: Article

References (10)

1. The dissociative anesthetics, ketamine and phencyclidine, selectively produce excitation of central mammalian neurons by N-methyl-aspartate
2. Effect of atropine on learning, extinction, retention and retrieval in rats
3. Anticonvulsant activity of (+)-5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5, 10-imine (MK-801), a substance with potent anticonvulsant, central sympathomimetic, and apparent anxiolytic properties
4. Restoration of shock-suppressed behavior by treatment with (+)-5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine (MK-801), a substance with potent anticonvulsant, central sympathomimetic, and apparent anxiolytic properties
5. The effect of phencyclidine and scopolamine on memory in rats
6. Comparative learning impairment and amnesia by scopolamine phencyclidine and ketamine
7. The novel anticonvulsant MK-801 interacts with central phencyclidine recognition sites in rat brain
8. Some effects of scopolamine on a passive avoidance response in rats
9. Phencyclidine-induced retrograde amnesia in mice
10. The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist