Anti‐Candida Activity and Toxicology of LY121019, a Novel Semisynthetic Polypeptide Antifungal Antibiotic

Annals of the New York Academy of Sciences

Volumn 544, Issue 1, 1988, Pages 294-309

  GORDEE, ROBERT S ^a   ZECKNER, DOUGLAS J ^a   HOWARD, LEONARD C ^a   ALBORN, WILLIAM E ^a   DEBONO, MANUEL ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACULEACIN A; AMPHOTERICIN B; CILOFUNGIN; CLOTRIMAZOLE; FLUCYTOSINE; MICONAZOLE; NYSTATIN;

ANIMAL EXPERIMENT; ANTIFUNGAL ACTIVITY; CANDIDA ALBICANS; CANDIDIASIS; DOG; DRUG ACTIVITY; DRUG TOXICITY; FUNGUS; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL;

ANIMAL; ANTIBIOTICS, ANTIFUNGAL; CANDIDA; CANDIDA ALBICANS; MICE; MICROBIAL SENSITIVITY TESTS; PEPTIDES; SPECIES SPECIFICITY;

EID: 0024155609     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1988.tb40415.x     Document Type: Article

References (8)

1. in vitro and in vivo anti‐Candida activity and toxicology of LY121019
2. On the mode of action of a new antifungal antibiotic, aculeacin A: Inhibition of cell wall synthesis in Saccharomyces cerevisiae
3. Studies on the mechanism of antifungal action of aculeacin A
4. Cell wall of pathogenic yeasts and implications for antimycotic therapy
5. Echinocandin inhibition of 1,3‐β‐D‐glucan synthase from Candida albicans
6. Effect of aculeacin A, a wall‐active antibiotic, on synthesis of the yeast cell wall
7. Oral Candida albicans in HIV infection
8. Comparative toxicological studies of amphotericin B methyl ester and amphotericin B in mice, rats, and dogs