-
2
-
-
85004809858
-
Effective hyposensitization in allergic rhinitis using a potent partially purified extract of house dust mite
-
Of interest, Demonstration of clinically effective D. pteronyssinus immunotherapy using a potent preparation containing known amounts of Der p I.
-
(1988)
Clin Allergy
, vol.18
, pp. 501-508
-
-
Ewan1
Alexander2
Snaps3
Ind4
Agrell5
Dreborg6
-
3
-
-
85004905442
-
4 antibody level is associated with failure of immunotherapy with inhalant allergens
-
Of interest, An analysis of data from several studies on immunotherapy for inhalant allergens concluded that high IgG4 levels were associated with, and could predict, treatment failure.
-
(1987)
Clin Allergy
, vol.17
, pp. 459-468
-
-
Djurup1
Malling2
-
5
-
-
0023617179
-
Double-blind, placebo-controlled immunotherapy with mixed grass-pollen allergoids. 1. Rush immunotherapy with allergoids and standardized orchard grass pollen extract
-
Of interest, A grass pollen allergoid produced the same clinical improvement but with more side effects than a standard extract.
-
(1987)
J Allergy Clin Immunol
, vol.80
, pp. 591-598
-
-
Bousquet1
Heijaoui2
Skassa-Brociek3
Glurin4
Maasch5
Dhiert6
Michel7
-
6
-
-
0023727708
-
Preparation of patient-related allergens for hyposensitization
-
Of interest, A proposal that treatment extracts could be tailor-made to match the patient's allergen-specific IgG or IgE responses.
-
(1988)
Allergy
, vol.43
, pp. 552-564
-
-
Poulsen1
Søergaard2
Weeks3
-
7
-
-
0023774406
-
Immunotherapy with partially purified and standardized tree pollen extracts. I. Clinical results from a three-year double-blind study of patients treated with pollen extracts either of birch or combinations of alder, birch and hazel
-
Of interest, Patients with allergy to tree pollens (birch, alder and hazel) responded as well to treatment with birch pollen alone as with a combination of birch, alder or hazel, matched to their IgE responses.
-
(1988)
Allergy
, vol.43
, pp. 353-362
-
-
Petersen1
Janniche2
Munch3
Wihl4
Böwadt5
Ipsen6
Løwenstein7
-
8
-
-
0023693592
-
Immunotherapy with partially purified and standardized tree pollen extracts. II. Results of skin prick tests and nasal provocation tests from a three-year doubleblind study of patients treated with pollen extracts either of birch or combination of alder, birch and hazel
-
Of interest, Treatment with birch pollen extract alone or patient-tailored extracts of birch, alder and hazel pollen were equally effective in reducing skin and nasal sensitivity to allergen.
-
(1988)
Allergy
, vol.43
, pp. 363-369
-
-
Wihl1
Ipsen2
Petersen3
Munch4
Janniche5
Løwenstein6
-
9
-
-
0023696018
-
Immunotherapy with partially purified and standardized tree pollen extracts. III. Specific IgE responses to the major allergens of alder birch and hazel pollen during immunotherapy
-
Of interest, Treatment with either birch pollen alone or a mixture of alder, birch and hazel was equally effective in reducing IgE responses to the major allergens of these pollens.
-
(1988)
Allergy
, vol.43
, pp. 370-377
-
-
Ipsen1
Schwakrz2
Wihl3
Petersen4
Munch5
Janniche6
Løwenstein7
-
11
-
-
0023193306
-
High dose grass pollen tablets used for hyposensitization in hay fever patients. A oneyear double blind placebo-controlled study
-
Of interest, A placebo-controlled trial demonstrating failure of oral immunotherapy in adults with grass pollen hay fever.
-
(1987)
Allergy
, vol.42
, pp. 451-455
-
-
Mosbech1
Dreborg2
Madsen3
Ohlsson4
Stahl Skov5
Taudorf6
Weeks7
-
12
-
-
0023730481
-
In vitro studies of degradation of birch and timothy pollen allergen preparations by human duodenal juice
-
Of interest, Human duodenal juice rapidly hydrolyses grass and tree pollen proteins at an almost equal rate.
-
(1988)
Allergy
, vol.43
, pp. 469-472
-
-
Einarrson1
Renck2
Taudorf3
-
13
-
-
0023900908
-
Sublingual allergen administration. I. Selective suppression of IgE production in rats by high allergen dose
-
Of interest, Sublingual allergen can lead to suppression of allergen-specific IgE sometimes with concomitant suppression of IgG in certain inbred strains of rat.
-
(1988)
Clin Allergy
, vol.18
, pp. 229-234
-
-
Holt1
Vines2
Britten3
-
14
-
-
0023838564
-
Diagnosis and immunotherapy of mould allergy.
-
Of interest, A poor clinical outcome was associated with an early rise in IgGl and to a lesser extent in IgG4.
-
(1988)
Allergy
, vol.43
, pp. 60-70
-
-
Mailing1
Djurup2
-
15
-
-
0023104072
-
Changes of house dust mite-specific IgE, IgG and IgG subclass antibodies during immunotherapy in patients with perennial rhinitis
-
Of interest, A study of the IgG subclass profile during immunotherapy, showing a steady rise in IgG4 and that a good clinical outcome was associated with the rate of increase of IgG4 antibodies.
-
(1987)
Int Arch Allergy Appl Immunol
, vol.82
, pp. 95-99
-
-
Nakagawa1
Kozeki2
Katagiri3
Fujita4
Yamashita5
Miyamoto6
Skvaril7
-
16
-
-
84909758426
-
D. pteronyssinus IgG and IgG subclass responses and efficacy of desensitization
-
Of interest, A study of house dust mite immunotherapy showing that rises in IgG1 and 4 Occurred in the clinically effective but not in ineffective regimes. When the patients in the effective group were subgrouped by clinical response, no significant differences in IgG1 and 4 were found.
-
(1989)
Clin Exp Allergy
, vol.19
, pp. 110
-
-
Ewan1
McHugh2
Kemeny3
-
17
-
-
0023634978
-
A subclass IgG4-specific antigen-binding radioimmunoassay (RIA): Comparison between IgG and IgG4 antibodies to food and inhaled antigens in adult atopic dermatitis after desensitization treatment and during development of antibody responses in children
-
Of outstanding interest, A study of IgG4 to various allergens, using a fluid phase antigen binding assay, in different clinical settings. Evidence is presented to suggest that cumulative dose and chronicity of exposure to allergen may influence the development of IgG4 responses.
-
(1987)
Journal of Allergy and Clinical Immunology
, vol.80
, pp. 622-630
-
-
Rowntree1
Platts-Mills2
Cogswell3
Mitchell4
-
18
-
-
0023128799
-
Eosinophil chemotactic activity in allergic patients during the birch pollen season: the effect of immunotherapy
-
Of outstanding interest, Shows that birch pollen immunotherapy blocks the seasonal rise in eosinophil chemotactic activity which occurred in untreated birch allergic patients.
-
(1987)
Int Arch Allergy Appl Immunol
, vol.82
, pp. 349-350
-
-
Rak1
Hakansson2
Venge3
-
19
-
-
0024399808
-
Reduction of increased serum neutrophil chemotactic activity following effective hyposensitization in house dust mite allergy
-
Of outstanding interest, (in press), House dust mite allergic patients were found to have raised levels of serum neutrophil chemotactic activity which fell to normal after clinically effective immunotherapy, but remained elevated in placebo-treated patients.
-
(1989)
Experimental Allergy"');">Clinical Experimental Allergy
, vol.19
-
-
McHugh1
Ewan2
-
20
-
-
0023871261
-
Lymphocyte proliferative response to the purified Dermatopbagoides farinae major allergen in untreated and hyposensitized atopic patients
-
Of interest, No differences could be detected in peripheral blood mononuclear cell responses to Der fI in normal subjects, allergic patients and hyposensitized patients.
-
(1988)
Allergy
, vol.43
, pp. 146-151
-
-
Cavaillon1
Fitting2
Guinnepain3
Rassemont4
David5
-
21
-
-
0023150591
-
Immunological changes after hyposensitization in house-dust-sensitive asthmatic children: A review
-
Of interest, A study of various inttnunological changes with house dust immunotherapy in children which showed a reduction in allergen induced IL-2 secretion by mononuclear cells.
-
(1987)
J Asthma
, vol.24
, pp. 19-27
-
-
Hsieh1
Lue2
Chiang3
-
22
-
-
0023185979
-
Decreased expression of high affinity inteRLEukin 2 receptors after hyposensitization to house dust
-
Of interest, There was no difference in IL-2 receptors detected by monoclonal antibody (anti-Tac) in allergic, hyposensitized and normal subjects, but proliferation of allergen stimulated lymphocytes was induced by low concentrations of recombinant IL-2 in untreated allergic patients only, suggesting that they have more high affinity IL-2 receptors.
-
(1987)
Ann Allergy
, vol.59
, pp. 57-62
-
-
Hsieh1
Wu2
-
23
-
-
0023722274
-
The effect of immunotherapy on bronchial hyperresponsiveness and eosinophil cationic protein in pollen-allergic patients
-
Of outstanding interest, The levels of the eosinophil degranulation product, ECP, increased during the birch pollen season in untreated patients but not in patients treated with immunotherapy. Non-specific bronchial hyperreactivity correlated with ECP levels.
-
(1988)
J Allergy Clin Immunol
, vol.82
, pp. 470-480
-
-
Rak1
Löwhagen2
Venge3
-
25
-
-
6544296201
-
An analysis of reactions to three house dust mite desensitisation regimens
-
Of interest, A prospective study of immediate ( < 2 h) and late ( 〉 2 h) reactions to different immunotherapy regimens, studying incidence, type and timing of reactions and their relation to dose and possible risk factors.
-
(1988)
Allergy
, vol.43
, pp. 43
-
-
Ewan1
Lavelle2
Snaps3
Alexander4
Agrell5
Dreborg6
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