Transport and metabolism of dexamethasone in the dually perfused human placenta

Reproductive Toxicology

Volumn 2, Issue 1, 1988, Pages 37-43

  Smith, Mary Alice ^a,b   Thomford, Peter J ^a,b   Mattison, Donald R ^a,b   Slikker, William ^a,b  

^a NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

Dexamethasone; Glucocorticoids; Human placenta; Metabolism; Perfusion; Transport

Indexed keywords

DEXAMETHASONE;

ARTICLE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; IN VITRO STUDY; METABOLISM; PERFUSION; PHYSIOLOGY; PLACENTA; TRANSPORT AT THE CELLULAR LEVEL;

BIOLOGICAL TRANSPORT; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEXAMETHASONE; HUMANS; PERFUSION; PLACENTA;

EID: 0024122634     PISSN: 08906238     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0890-6238(88)80007-8     Document Type: Article

References (12)

1. Risks and benefits of steroid therapy for the prevention of hyaline membrane disease
2. A controlled trial of antepartum glucocorticoid treatment for prevention of respiratory distress syndrome in premature infants
3. Antenatal prevention of the neonatal respiratory distress syndrome: Benefits and potential risks for the mother and the infant
4. Effect of antenatal dexamethasone administration on the prevention of respiratory distress syndrome
5. In vitro metabolism of prednisolone, dexamethasone, betamethasone, and Cortisol by the human placenta
6. The transfer and metabolism of corti-costeroids in the perfused human placenta
7. Transplacental metabolism of dexamethasone and Cortisol in the late gestational age rhesus monkey (Macaca mulatto)
8. Transfer across the perfused human placenta of antipyrine, sodium and leucine
9. Human placenta in vitro: Characterization during 12th of dual perfusion
10. The pharmacokinetics of phenytoin in perfused human placenta
11. Steroid 11β-ol dehydrogenase in human placenta
12. Placental steroid dehydrogenase: Assessment with a nonhuman primate in situ placental perfusion model