Optimal equidose inputs and role of measurement error for estimating the parameters of a compartmental model of glucose kinetics from continuous- and discrete-time optimal samples

Mathematical Biosciences

Volumn 89, Issue 2, 1988, Pages 135-147

  Cobelli, Claudio ^a,b   Thomaseth, Karl ^a,b  

^a Istituto di Ingeneria Biomedica del CNR   (Italy)

^b UNIVERSITY OF PADOVA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY - GLUCOSE IN BODY FLUIDS; MATHEMATICAL PROGRAMMING, LINEAR; MEASUREMENT ERRORS; TIME MEASUREMENT;

COMPARTMENTAL MODEL; DISCRETE-TIME OPTIMAL SAMPLES; GLUCOSE KINETICS; OPTIMAL EQUIDOSE INPUTS; OPTIMAL INPUT;

BIOMEDICAL ENGINEERING;

GLUCOSE;

MATHEMATICAL MODEL; NONHUMAN; PHARMACOKINETICS; THEORETICAL STUDY;

EID: 0024035142     PISSN: 00255564     EISSN: None     Source Type: Journal    
DOI: 10.1016/0025-5564(88)90095-8     Document Type: Article

References (5)

1. Optimal input design for identification of compartmental models. Theory and application to a model of glucose kinetics
2. The minimal model of glucose disappearance: Optimal input studies
3. Optimal design of multioutput sampling schedules. Software and applications to endocrine-metabolic and pharmacokinetic models
4. Robust sampling designs for compartmental models under large prior eigenvalue uncertainties
5. On optimality of the impulse input for linear system identification