Constitutive Production of Platelet-derived Growth Factor-like Proteins by Human Prostate Carcinoma Cell Lines

Cancer Research

Volumn 48, Issue 7, 1988, Pages 1930-1935

  Sitaras, Nikolaos M ^a   Sariban, Eric ^a   Bravo, Martin ^a   Pantazis, Panayotis ^a   Antoniades, Harry N ^a  

^a DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PLATELET DERIVED GROWTH FACTOR; RADIOISOTOPE;

CELL CULTURE; CYTOCHEMISTRY; CYTOLOGY; HUMAN; HUMAN CELL; MALE; PROSTATE CARCINOMA; TUMOR CELL LINE;

CARCINOMA; CELL LINE; FLUORESCENT ANTIBODY TECHNIQUE; HUMAN; MALE; MOLECULAR WEIGHT; NEOPLASM PROTEINS; PLATELET-DERIVED GROWTH FACTOR; PROSTATIC NEOPLASMS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENES; RECEPTORS, CELL SURFACE; RECEPTORS, PLATELET-DERIVED GROWTH FACTOR; RNA, NEOPLASM; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TRANSCRIPTION, GENETIC;

EID: 0023951176     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: None     Document Type: Article

References (42)

1. Antoniades, H. N., Pantazis, P., and Owen, A. J. Human platelet-derived growth factor and the sis/PDGF-2 gene. Oncogenes, Genes and Growth Factors. G. Guroff (ed.), pp. 1–39. New York: John Wiley Sons, Inc., 1987.
2. Antoniades, H. N., and Owen, A. J. Human platelet-derived growth factor. Horm. Proteins Peptides, 12:231-277, 1984.
3. Heldin, C. H., Betsholtz, C., Johnsson, A., Nister, M., Ek, B., Ronnstrand, L., Wasteson, A., and Westermark, B. Platelet-derived growth factor mechanism of action and relation to oncogenes. J. Cell. Sci. 3 (Suppl.); 65–76, 1985.
4. Antoniades, H. N., and Hunkapiller, M. W. Human platelet-derived growth factor (PDGF): amino-terminal amino acid sequence. Science (Wash. DC), 220:963-965,1983.
5. Johnsson, A., Heldin, C. H., Wasteson, A., Westermark, B., Deuel, T. F., Huang, J. S. Seeburg, P. H., Gray, E., Ullrich, A., Scrace, G., Stroobant, P., and Waterfield, M. D. The c-sis gene encodes a precursor of the β chain of platelet-derived growth factor. EMBO J., 3:921-928,1984.
6. Betsholtz, C., Johnsson, A., Heldin, C. H., Westermark, B., Lind, P., Urdea, M. S., Eddy, R., Shows, T. B., Philpott, K., Mellor, A., Knott, T. J., and J. Scott. cDNA sequence and chromosomal localization of human platelet-derived growth factor A-chain and its expression in tumor cell lines. Nature (Lond.), 320:695-699,1986.
7. Swan, D. C., McBride, O. W., Robbins, K. C., Keithley, D. A., Reddy, E. P., and Aaronson, S. A. Chromosomal mapping of the simian sarcoma virus one gene analog in human cells. Proc. Natl. Acad. Sci. USA, 79: 4691–4695, 1982.
8. Dalla-Favera, R., Gallo, R., Giallongo, C., and Croce, C. Chromosomal localization of the human homolog (c-sis) of the simian sarcoma virus one gene. Science (Wash. DC), 218:686-688,1982.
9. Rao, C. D., Igaraashi, H., Chin, I. M., Robbins, K. C., and Aaronson, S. A. Structure and sequence of the human c-sis platelet-derived growth factor 2(sis/PDGF 2) transcriptional unit. Proc. Natl. Acad. Sci. USA, 83: 2392–2396, 1986.
10. Doolittle, R. F., Hunkapiller, M. W., Hood, L. E., Devare, S. G., Robbins, K. C., Aaronson, S. A., and Antoniades, H. N. Simian sarcoma virus one gene, v-sis, is derived from the gene (or genes) encoding a platelet-derived growth factor. Science (Wash. DC), 221:275-277,1983.
11. Waterfield, M. D., Scrace, G. T., Whittle, N., Stroobant, P., Johnsson, A., Wasteson, A., Westermark, B., Heldin, C. H., Huang, J. S., and Deuel, T. F. Platelet-derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virus. Nature (Lond.), 304:35-39, 1983.
12. Josephs, S. F., Guo, C., Ratner, L., and Wong-Staal, F. Human proto-oncogene nucleotide sequences corresponding to the transforming region of simian sarcoma virus. Science (Wash. DC), 223:487-491,1984.
13. Chiu, I. M., Reddy, E. P., Givol, D., Robbins, K. C., Tronick, S. R., and Aaronson, S. A. Nucleotide sequence analysis identifies the human c-sis proto-oncogene as a structural gene for platelet-derived growth factor. Cell, 37:123-129, 1984.
14. Antoniades, H. N. Platelet-derived growth factor and malignant transformation. Biochem. Pharmacol., 33:2823-2828, 1984.
15. Heldin, C. H., and Westermark, B. Growth factors: mechanism of action and relation to oncogenes. Cell, 37:9-20, 1984.
16. Bronzert, D. A., Pantazis, P., Antoniades, H. N., Kasid, A., Davidson, N., Dickson, R. B., and Lippman, M. E. Synthesis and secretion of PDGF-like growth factor by human breast cancer cell lines. Proc. Natl. Acad. Sci. USA, 84:5763-5767, 1987.
17. Pantazis, P., Sariban, E., Kufe, D., and Antoniades, H. N. Induction of c-sis gene expression and synthesis of platelet-derived growth factor in human myeloid leukemia cells during monocytic differentiation. Proc. Natl. Acad. Sci. USA, 83:6455-6459, 1986.
18. Papayanopoulou, T. H., Raines, E., Collins, S., Nakamoto, B., Tweeddale, M., and Ross, R. Constitutive and inducible secretion of platelet-derived growth factor analogs by human leukemic cell lines coexpressing erythroid and megakaryocytic markers. J. Clin. Invest, 79:859-866,1987.
19. Alitalo, R., Andersson, L. C., Betsholtz, C., Nilsson, K., Westermark, B., Heldin, C. H., and Alitalo, K. Induction of platelet-derived growth gene expression during megakaryoblastic and monocytic differentiation of human leukemia cell lines. EMBO J., 6:1213-1218,1987.
20. Pantazis, P., Sariban, E., Bohan, C. A., Antoniades, H. N., and Kalyanaraman, V. S. Synthesis of PDGF by cultured human T cells transformed with HTLV-I and II. Oncogene, 1:285-289,1987.
21. Mickey, D. D., Stone, K. R., Wunderli, H., Mickey, G. H., Vollmer, R. T., and Paulson, D. F. Heterotransplantation of a human prostate adenocarcinoma cell line in nude mice. Cancer Res., 37:4049-4058,1977.
22. Stone, K. R., Mickey, D. D., Wunderli, H., Mickey, G. H., and Paulson, D. F. Isolation of a human prostate carcinoma cell line (DU 145). Int. J. Cancer, 21:274-281, 1978.
23. Kaighn, M. E., Lechner, J. F., Narayan, K. S., and Jones, L. W. Prostate carcinoma: tissue culture cell lines. Natl. Cancer. Inst. Monogr., 49:17-21, 1978.
24. Kaighn, M. E., Narayan, K. S., Ohnuki, Y., Lechner, J. F., and Jones, L. W. Establishment and characterization of a human prostatic carcinoma cell line (PC-3). Invest. Virol., 17:16-23, 1979.
25. Chirgwin, J. M., Przybyla, A. E., MacDonald, R. J., and Rutter, W. J. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry, 18:5294-5299,1979.
26. Thomas, P. Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose. Proc. Natl. Acad. Sci. USA, 77: 5201–5205, 1980.
27. Betsholtz, C., Johnsson, A., Heldin, C. H., Westermark, B., Lind, P., Urdea, M. S., Eddy, R., Shows, T. B., Philpott, K., Mellor, A. L., Knott, T. J., and Scott, J. cDNA sequence and chromosomal localization of human platelet-derived growth factor A-chain and its expression in tumor cell lines. Nature (Lond.), 320:695-699,1986.
28. Ratner, L., Josephs, S. F., Jarrett, R., Reitz, M. S., and Wong-Staal, F. Nucleotide sequence of transforming human c-sis cDNA clones with homology to platelet-derived growth factor. Proc. Natl. Acad. Sci. USA, 13:5007-5018, 1985.
29. Pantazis, P., Pelicci, P. G., Dalla-Favera, R., and Antoniades, H. N. Synthesis and secretion of proteins resembling platelet-derived growth factor by human glioblastoma and fibrosarcoma cells in culture. Proc. Natl. Acad. Sci. USA, 82:2404-2408, 1985.
30. Antoniades, H. N., and Pantazis, P. Structural and functional identification of platelet-derived growth factor-like proteins produced by mammalian cells. Methods Enzymol., 146:22-40, 1987.
31. Betsholtz, C., Westermark, B., Ek, B., and Heldin, C. H. Coexpression of a PDGF-like growth factor and PDGF receptors in a human osteosarcoma cell line: implications for autocrine receptor activation. Cell, 39:447-457,1984.
32. Graves, D. T., Owen, A. J., and Antoniades, H. N. Demonstration of receptors for a PDGF-like mitogen on human osteosarcoma cells. Biochem. Biophys. Res. Commun., 129:56-62,1985.
33. Pantazis, P., and Bonner, W. M. Quantitative determination of histone modification: H2A acetylation and phosphorylation. J. Biol. Chem., 256: 4669-4675,1981.
34. Rijnders, A. W. M., van der Korput, J. A. G. M., van Steenbrugge, G. J., Romijn, J. C., and Trapman, J. Expression of cellular oncogenes in human prostatic carcinoma cell lines. Biochem. Biophys. Res. Commun., 132:548-554,1985.
35. Westermark, B., Johnsson, A., Paulson, Y., Betsholtz, C., Heldin, C. H., Heilyn, M., Rodeck, U., and Koprowski, M. Human melanoma cell lines of primary and metastatic one gene express the genes encoding the chains of platelet-derived growth factor (PDGF) and produce a PDGF-like growth factor. Proc. Natl. Acad. Sci. USA, 83:7197-7200,1986.
36. Eva, A., Robbins, K. S., Anderson, P. R., Srinivasan, A., Tronick, S. R., Reddy, E. P., Ellnore, N. W., Galen, A. T., Lautenberger, J. A., Papas, T. S., Westin, E. H., Song-Staal, F., Gallo, R. C., and Aaronson, S. A. Cellular genes analogous to retroviral one genes are transcribed in human tumor cells. Nature (Lond.), 295:116-119,1982.
37. Graves, D. T., Owen, A. J., Bath, R. K., Tempst, P., Winoto, A., Fors, L., Hood, L. E., and Antoniades, H. N. Detection of c-sis transcripts and synthesis of PDGF-like proteins by human osteosarcoma cells. Science (Wash. DC), 226:972-974,1984.
38. Graves, D. T., Owen, A. J., Williams, S. R., and Antoniades, H. N. Identification of processing events in the synthesis of platelet-derived growth factor-like proteins by human osteosarcoma cells. Proc. Natl. Acad. Sci. USA, 83: 4636-4640,1986.
39. Pantazis, P., Lanfrancone, L., Pelicci, P. G., Dalla-Favera, R., and Antoniades, H. N. Human leukemic cells synthesize and secrete proteins related to platelet-derived growth factor. Proc. Natl. Acad. Sci. USA, 83: 5526–5530, 1986.
40. Heldin, C. H., Westermark, B., and Wasteson, A. Specific receptors for platelet-derived growth factor on cells derived from connective tissue and glia. proc. Natl. Acad. Sci. USA, 78:3664-3668,1981.
41. Kelly, K., Cochran, B. H., Stiles, C. D., and Lede, B. Cell specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor. Cell, 35:603-610, 1983.
42. Greenberg, M. E., and Ziff, E. B. Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene. Nature (Lond.), 311:433,1984.