Effects of fasting and diabetes on some enzymes and transport of glutamate in cortex slices or synaptosomes from rat brain

Neurochemical Research

Volumn 13, Issue 3, 1988, Pages 243-248

  Galanopoulos, E ^a   Lellos, V ^a   Papadakis, M ^a   Philippids, H ^a   Palaiologos, G ^a  

^a UNIVERSITY OF ATHENS   (Greece)

Author keywords

brain cortex slices; diabetes; glutamate; glutamic acid decarboxylase; glutamine synthetase; Phosphate activated glutaminase; synaptosomes

Indexed keywords

GLUTAMATE DECARBOXYLASE; GLUTAMINASE; STREPTOZOCIN;

ANIMAL CELL; ANIMAL EXPERIMENT; BRAIN CORTEX; CALORIC RESTRICTION; DIABETES MELLITUS; MALE; NONHUMAN; SYNAPTOSOME; TISSUE SLICE;

ANIMAL; CEREBRAL CORTEX; DIABETES MELLITUS, EXPERIMENTAL; FASTING; GLUTAMATE DECARBOXYLASE; GLUTAMATE-AMMONIA LIGASE; GLUTAMATES; GLUTAMIC ACID; GLUTAMINASE; IN VITRO; MALE; RATS; RATS, INBRED STRAINS; SUPPORT, NON-U.S. GOV'T; SYNAPTOSOMES;

EID: 0023950858     PISSN: 03643190     EISSN: 15736903     Source Type: Journal    
DOI: 10.1007/BF00971540     Document Type: Article

References (31)

1. Effects of branched chain amino acids, pyruvate or ketone bodies on the free amino acid pool and release from brain cortex slices of normal and streptozotocin-diabetic rats
2. Glutamine and glucose as precursors of transmitter amino acids: ex vivo studies
3. The Metabolic compartmentation concept
4. Glutamate metabolizing enzymes and its transport in brain cortex from normal and diabetic rats
5. The effect of diabetes, insulin and the redox potential on leucine metabolism in isolated rat hemidiaphragm
6. Interaction of leucine, glucose and ketone metabolism in rat brain in vitro
7. Depolarization-induced phosphorylation of specific proteins, mediated by calcium ion influx, in rat brain synaptosomes
8. Glutamine Synthesis
9. The attachment of glutamine synthetase to brain membranes
10. A radiochemical assay for glutamine synthetase, and activity of the enzyme in rat tissues
11. Relative activities of glutamine synthetase and glutaminase in mammalian synaptosomes
12. Glutamine—A major substrate for nerve endings
13. Effect of cortico-striate pathway lesion on the activities of enzymes involved in the synthesis and metabolism of amino acid neurotransmitters in the striatum
14. A rapid method for assaying enzymes whose substrates and products differ by charge. Application to brain l-glutamate decarboxylase
15. The structural specificity of the high affinity uptake of l-glutamate and l-aspartate by rat brain slices
16. Characteristics of glutamine vs. glutamate transport in isolated glia and synaptosomes
17. A comparison of inhibition of steady state, net transport and exchange fluxes of amino acids in brain slices
18. Postnatal changes in the potassium-stimulated calcium-dependent release of radioactive GABA and glycine from slices of rat central nervous tissue
19. Membrane properties and aging. In vivo and in vitro effects of ethanol on synaptosomal γ-aminobutyric acid (GABA) release
20. The effect of thiol reagents on GABA transport in rat brain synaptosomes
21. Protein measurement with Folin phenol reagent
22. A rapid radioactive assay for glutamine synthetase, glutaminase, asparagine synthetase and asparaginase
23. Glutamine synthetase: Glial localization in brain
24. Fine structural localization of glutamine synthetase in astrocytes of rat brain
25. Immunohistochemistry of glutamine synthetase
26. Glutaminase and glutamine synthetase activity in synaptosomes bulk-isolated glia and neurons
27. The distribution of glutamine synthetase in subcellular fractions of rat brain
28. Regulatory properties of membrane form of phosphate-dependent glutaminase of synaptosomes and mitochondria in rat brain
29. Phosphate-dependent soluble glutaminase from rat brain. Role of different agents in the modulation of its activity