Strong attenuation of ischemic and postischemic brain edema in rats by a novel free radical scavenger

Stroke

Volumn 19, Issue 4, 1988, Pages 480-485

  Abe, Koji ^a   Yuki, Satoshi ^a   Kogure, Kyuya ^a  

^a TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Abstract; Cerebral edema; Cerebral ischemia; Free radicals; Rats

Indexed keywords

FATTY ACID; POLYPHOSPHOINOSITIDE;

AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; BRAIN CORTEX; BRAIN EDEMA; INTERNAL CAROTID ARTERY OCCLUSION; INTRAVENOUS DRUG ADMINISTRATION; MALE; MIDDLE CEREBRAL ARTERY; NONHUMAN; RAT;

ANIMAL; BODY WATER; BRAIN EDEMA; BRAIN ISCHEMIA; CEREBRAL CORTEX; FATTY ACIDS, NONESTERIFIED; FREE RADICALS; MALE; OXYGEN; PHOSPHATIDYLINOSITOL PHOSPHATES; PHOSPHATIDYLINOSITOLS; RATS; RATS, INBRED STRAINS;

EID: 0023947826     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/01.STR.19.4.480     Document Type: Article

References (41)

1. Flamm ES, Demopoulos HB, Seligman ML, Poser RG, Ransohoff J: Free radicals in cerebral ischemia. Stroke 1978;9:445-447
2. Siesjfl BK: Cell damage in the brain: A speculative synthesis. J Cereb Blood Flow Metab 1981;1:155-185
3. McCord JM: Oxygen-de rived free radicals in post-ischemic tissue injury. N Engl J Med 1985;312:159-163
4. Kogure K, Arai H, Abe K, Nakano M: Free radical damage of the brain following ischemia. Prog Brain Res 1985;63:237-259
5. Demopoulos HB: The basis of the free radical pathology. Fed Proc 1973;32:1859-1861
6. Adesuyi SA, Cockrell CS, Gramache DA, Ellis EF: Lipoxygenase metabolism of arachidonic acid in brain. J Neurochem 1985;45:770-776
7. TominagaT, ImaizumiS, UenoharaK, Suzuki J, Fujita Y: Free radical reaction evaluated by chemiluminescence and electron spin resonance (ESR) in rat hypoxic or ischemic brain homogenate. J Cereb Blood Flow Metab 1985;5:s293-s294
8. Halliwell B, Gutteridge JMC: Oxygen toxicity, oxygen radicals, transition meta ls and disease. Biochem J 1984;219:1-14
9. Slater TF: Free-radical mechanisms in tissue injury. Biochem J 1984;222:1-15
10. Halliwell B, Gutteridge JMC: Oxygen radicals and the nervous system. Trends Nerv Sys 1985;22-26
11. 3 injection into rat isocortex. Brain Res 1983;277:393-396
12. Watson BD, Busto R, Goldberg WJ, Santiso M, Yoshida S, Ginsberg M: Lipid peroxidation in vivo induced by reversible global ischemia in rat brain. J Neurochem 1984;42:268-274
13. Yoshida S, Abe K, Busto R, Watson BD, Kogure K, Ginsberg MD: Influence of transient ischemia on lipid-soluble antioxidants, free fatty acids and energy metabolites in rat brain. Brain Res 1982;245:307-316
14. Chan PH, Fishman RA: Brain edema: Induction in cortical slices by polyunsatu rated fatty acids. Science 1978;201:358-360
15. Chan PH, Fishman RA: Transient formation of superoxide radicals in polyun saturat ed fatty acid-induced brain swelling. JNeurochem 1980;35:1004-1007
16. 2+- and ascorbic acidstimulated lipid peroxidation in vitro. J Neurochem 1980;34:1630-1638
17. Chan PH, Yurko M, Fishman RA: Phospholipid degradation and cellular edema induced by free radicals in brain cortical slices. J Neurochem 1982;38:525-531
18. Abe K, Kogure K, Arai H, Nakano M: Ascorbate induced lipid peroxidation results in loss of receptor binding in Tris, but not in phosphate, buffer. Biochem Int 1985;11:341-348
19. Koide T, Gotoh O, Asano T, Takakura K: Alterations of the eicosanoid synthetic capacity of rat brain microvessels following ischemia: Relevance to ischemic brain edema. J Neurochem 1985;44:85-93
20. Asano T, Gotoh O, Koide T, Takakura K: Ischemic brain edema following occlusion of the middle cerebral artery in the rat. II: Alteration of the eicosanoid synthesis profile of brain microvessels. Stroke 1985;16:110-113
21. Harris RJ, Lindquist C, Kamiya K, KuyamaH, Branston NM, Symon L: The role of leucotrienes in the formation of cerebral edema. J Cereb Blood Flow Metab 1983;3:s285-s286
22. Dempsey RJ, Roy MW, Cowen DE, Maley ME: Lipoxygenase metabolites of arachidonic acid and the development of ischaemic cerebral oedema. Neurol Res 1986;8:53-56
23. Koizumi J, Yoshida Y, Nakazawa T, Ooneda G: Experimental studies of ischemic brain edema. 1. A new experimental model of cerebral embolism in rats in which recirculation can be introduced in the ischemic area. Jpn J Stroke 1986;8:1-7
24. Nishi H, Yuki S, Watanabe T, Sakurai H: The development of a Hossman type model of bilateral hemispheric ischemia in rats (abstract). Nippon Yakurigaku Zasshi 1986;s40:85
25. Watanabe T, Sakurai H, Yuki S, Nishi H: An experimental model of hemispheric brain edema in rats induced by the intra carotid artery injection of polyvinyl acetate (abstract). Nippon Yakurigaku Zasshi 1986;s40:259
26. Ponten U, Ratcheson RA, Salford LG, Siesjo BK: Optimal freezing conditions for cerebral metabolites in rats. J Neurochem 1973;21:1127-1138
27. Abe K, Kogure K, Yamamoto H, Imazawa M, Miyamoto K: Mechanism of arachidonic acid liberation during ischemia in gerbil cerebral cortex. J Neurochem 1987;48:503-509
28. Yasuda H, Kishiro K, Izumi N, Nakanishi M: Biphasic liberation of arachidonic and stearic acids during cerebral ischemia. J Neurochem 1985;45:168-172
29. Ikeda M, Yoshida S, Busto R, Santiso M, Ginsberg MD: Poh/phosphoinositides as a probable source of brain free fatty acids accumulated at the onset of ischemia. J Neurochem 1986;47:123-132
30. Hee-Cheong M, Fletcher T, Kryski SK, Severson DL Diacylglycerol lipase and kinase activities in rat brain microvessels. Biochim BiophysActa 1985;833:59-68
31. Dawson RMC: Enzymic pathways of phospholipid metabolism in the nervous system, in Eichberg J (ed): Pnospholipids in Nervous Tissues. New York, Wiley-Interscience, 1985, pp 45-78
32. Klatzo I: Concepts of ischemic injury associated with brain edema, in Inaba Y, Klatzo I, Spatz M (eds): Brain Edema. Berlin, Springer-Verlag, 1985, pp 1-5
33. HossmanKA: The pathophysiology of ischemic brain swelling, in Inaba Y, Klatzo I, Spatz M (eds): Brain Edema. Berlin, Springer-Verlag, 1985, pp 367-384
34. Kogure K, Busto R, Scheinberg P: The role of hydrostatic pressure in ischemic brain edema. Ann Neurol 1981;9:273-282
35. Kukreja RC, Kontos HA, Hess ML, Ellis EF: PGH synthase and lipoxygenase generate superoxide in the presence of NADH or NADPH. Ore Res 1986;59:612-619
36. 2 into rat isocortex. Brain Res 1982;246:113-119
37. Chan PH, Fishman RA, CaronnaJ, SchmidleyJW, PrioleanG, Lee J: Induction of brain edema following intracerebral injection of arachidonic acid. Ann Neurol 1983;13:625-632
38. Chan PH, Schmidley JW, Fishman RA, Longar SM: Brain injury, edema, and vascular permeability changes induced by oxygen-derived free radicals. Neurology 1984;34:315-320
39. Tanaka J, Kogure K, Ohtomo H: Protective effect of a novel free radical scavenger on acute cerebral ischemia. J Cereb Blood Flow Metab 1985;5:s323-s324
40. Capdeville C, Allix M, Plotkine M, Boulu G: Effect of cyclooxygenase, lipoxygenase, or thromboxane synthetase inhibitors on the four-vessel model of cerebral ischemia. J Cereb Blood Flow Metab 1985;5:s325-s326
41. Yoshida S, Busto R, Watson BD, Santiso M, Ginsberg MD: Post ischemic cerebral lipidperoxidation in vitro: Modification by dietary vitamin E. J Neurochem 1985;44:1593-1601