A potential role for excitotoxins in the pathophysiology of spinal cord injury

Annals of Neurology

Volumn 23, Issue 6, 1988, Pages 623-626

  Faden, Alan I ^a,b   Simon, Roger P ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SAN FRANCISCO GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIZOCILPINE; N METHYLASPARTIC ACID;

AGED; ANIMAL CELL; INTRATHECAL DRUG ADMINISTRATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL CORD INJURY;

ANIMAL; ANTICONVULSANTS; ASPARTIC ACID; DIBENZOCYCLOHEPTENES; DISEASE MODELS, ANIMAL; DIZOCILPINE MALEATE; MALE; MOTOR ACTIVITY; N-METHYLASPARTATE; RATS; RATS, INBRED STRAINS; RECEPTORS, N-METHYL-D-ASPARTATE; RECEPTORS, NEUROTRANSMITTER; SPINAL CORD INJURIES; STEREOISOMERISM; SUPPORT, U.S. GOV'T, P.H.S.; TOXINS;

EID: 0023946078     PISSN: 03645134     EISSN: 15318249     Source Type: Journal    
DOI: 10.1002/ana.410230618     Document Type: Article

References (21)

1. The toxic effect of sodium l‐glutamate on the inner layers of the retina
2. Cytotoxic effects of acidic and sulphur containing amino acids on the infant mouse central nervous system
3. Excitatory amino acid Neurotoxins:selectivity, specificity, and mechanisms of action
4. Possible therapeutic applications of antagonists of excitatory amino acid neurotransmitters
5. Ionic dependence of glutamate neurotoxicity
6. Blockade of N‐methyl‐d‐aspartate receptors may protect against ischemic damage in the brain
7. Hypoglycemia‐induced neuronal damage prevented by an N‐methyl‐d‐asparate antagonist
8. Role of excitatory amino acid receptors in mono‐ and polysynaptic excitation in the cat spinal cord
9. Kynurenic acid inhibits synaptic and acidic amino acid‐induced responses in the rat
10. Recent pharmacological advances in experimental spinal injury:theoretical and methodological considerations
11. Extracellular calcium activity in the injured spinal cord
12. The novel anticonvulsant MK‐801 is a potent N‐methyl‐d‐aspartate antagonist
13. Increased dynorphin immunoreactivity in spinal cord after traumatic injury
14. Dynorphin induces partially reversible paraplegia in the rat
15. Objective clinical assessment of motor function after experimental spinal cord injury in the rat
16. Pharmacotherapy in spinal cord injury:a critical review of recent developments
17. The role of calcium in spinal cord injury
18. Longitudinal extension of oedema in experimental spinal cord injury—evidence for two types of posttraumatic oedema
19. NMDA‐receptor activation increases cytoplasmic calcium concentration in cultured spinal cord neurons
20. Effects of excitatory neurotransmitter amino acids on swelling of rat brain cortical slices
21. Inhibition of excitatory neurotransmission with kynurenate reduces brain edema in neonatal anoxia