Thymic lymphoma induction by the ak.t8 murine retrovirus

Journal of Experimental Medicine

Volumn 167, Issue 3, 1988, Pages 1259-1264

  Staal, Stephen P ^a,b   Hartley, Janet W ^a,b  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; CARCINOGENICITY; MOUSE; NONHUMAN; ONCOGENE; RETROVIRUS; SOUTHERN BLOTTING; THYMUS LYMPHOMA;

ANIMAL; DEFECTIVE VIRUSES; DNA, NEOPLASM; GAMMARETROVIRUS; GENES, VIRAL; LYMPHOMA; MICE; MICE, INBRED AKR; ONCOGENES; PROVIRUSES; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; THYMUS NEOPLASMS;

EID: 0023945139     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.167.3.1259     Document Type: Article

References (26)

1. Staal, S. P., J. W. Hartley, and W. P. Rowe. 1977. Isolation of transforming murine leukemia viruses from mice with a high incidence of spontaneous lymphoma. Proc. Natl. Acad. Sci. USA. 74:3065.
2. Staal, S. P. 1987. Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarci-
3. Hartley, J. W., and W. P. Rowe. 1976. Naturally occurring murine leukemia viruses in wild mice: characterization of a new "amphotropic" class. J. Virol. 19:19.
4. Rasheed, S., M. B. Gardner, and E. Chan. 1976. Amphotropic host range of naturally occurring wild mouse leukemia viruses. J. Virol. 19:13.
5. Hartley, J. W., N. K. Wolford, L. J. Old, and W. P. Rowe. 1977. A new class of murine leukemia virus associated with development of spontaneous lymphomas. Proc. Natl. Acad. Sci. USA. 74:789.
6. Peebles, P. T. 1975. An in vitro focus-induction assay for xenotropic murine leukemia viruses. Virology. 65:128.
7. Cloyd, M. W., J. W. Hartley, and W. P. Rowe. 1980. Lymphomagenicity of recombinant mink cell focus-inducing murine leukemia viruses. J. Exp. Med. 151:542.
8. Kozak, C. A., and W. P. Rowe. 1982. Genetic mapping of ecotropic murine leukemia virus-inducing loci in six inbred strains. J. Exp. Med. 155:524.
9. Cloyd, M. W., J. W. Hartley, and W. P. Rowe. 1981. Genetic study of lymphoma induction by AKR mink cell focus-inducing virus in AKR X NFS crosses. J. Exp. Med. 154:450.
10. Fredrickson, T. N., H. C. Morse III, and W. P. Rowe. 1984. Spontaneous tumors of NFS mice congenic for ecotropic murine leukemia virus induction loci.y. Natl. Cancer Inst. 73:521.
11. Furth, J., H. R. Seibold, and R. R. Rathbone. 1933. Experimental studies on lymphomatosis of mice. Am. J. Cancer 19:521.
12. Lynch, C. J. 1954. The r.I.L. strain of mice: its relation to the leukemic aK strain and aKR substrains. J Natl. Cancer Inst. 15:161.
13. Rowe, W. P., and T. Pincus. 1972. Quantitative studies of naturally occurring murine leukemia virus infection of AKR mice. J Exp. Med. 135:429.
14. Rowe, W. P. 1978. Leukemia virus genomes in the chromosomal DNA of the mouse. Harvey Lect. 71:173.
15. Elder, J. H., J. W. Gautsch, F. C.Jensen, R. A. Lerner, J. W. Hartley, and W. P. Rowe. 1977. Biochemical evidence that MCF murine leukemia viruses are envelope (env) gene recombinants. Proc. Natl. Acad. Sci. USA. 74:4676.
16. Chattopadhyay, S. K., M. W. Cloyd, D. L. Linemeyer, M. R. Lander, E. Rands, and D. R. Lowy. 1982. Cellular origin and role of mink cell focus-forming viruses in murine thymic lymphomas. Nature (Lond.) 295:25.
17. Cloyd, M. W. 1983. Characterization of target cells for MCF viruses in AKR mice. Cell. 32:217.
18. Li, Y., C. A. Holland, J. W. Hartley, and N. Hopkins. 1984. Viral integration near c-myc in 10-20% of mcf 247-induced AKR lymphomas. Proc. Natl. Acad. Sci. USA. 81:6808.
19. Steffen, D. 1984. Proviruses are adjacent to c-myc in some murine leukemia virus-induced lymphoma. Proc. Natl. Acad. Sci. USA. 81:2097.
20. Corcoran, L. M., J. M. Adams, A. R. Dunn, and S. Cory. 1984. Murine T lymphomas in which the cellular myc oncogene has been activated by retroviral insertion. Cell. 37:113.
21. Selten, G., H. T. Cuypers, M. Zijlstra, C. Melief, and A. Berns. 1984. Involvement of c-myc in MuLV-induced T cell lymphomas in mice: frequency and mechanisms of 3 activation. EMBO (Eur. Mol. Biol. Organ.) J. 3:3215
22. ODonnell, P. V., E. Fleissner, H. Lonial, C. F. Koehne, and A. Reicin. 1985. Early clonality and high-frequency proviral integration into the c-myc locus in AKR leuke-mias.y. Virol. 55:500.
23. Selten, G., H. T. Cuypers, and A. Berns. 1985. Proviral activation of the putative oncogene Pim-1 in MuLV induced T-cell lymphomas. EMBO (Eur. Mol. Biol. Organ.) J. 4:1793.
24. Tsichlis, P. N. 1987. Oncogenesis by Moloney murine leukemia virus. Anticancer Res. 7:171.
25. Villeneuve, L., E. Rassart, P. Jolicoeur, M. Graham, and J. M. Adams. 1986. Proviral integration site Mis-1 in rat thymomas corresponds to the pvt-1 translocation breakpoint in murine plasmacytomas. Mol. Cell. Biol. 6:1834.
26. Vijaya, S., D. L. Steffen, C. Kozak, and H. L. Robinson. 1987. Dsi-1, a region with frequent proviral insertions in Moloney murine leukemia virus-induced rat thymomas. J Virol. 61:1164.