Predicting creatinine clearance and renal drug clearance in obese patients from estimated fat-free body mass

The American Journal of Medicine

Volumn 84, Issue 6, 1988, Pages 1053-1060

  Salazar, Daniel E ^a   Corcoran, George B ^b  

^a UNIVERSITY AT BUFFALO   (United States)

^b UNIVERSITY OF NEW MEXICO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; CREATININE CLEARANCE; DRUG CLEARANCE; FEMALE; HUMAN; HUMAN EXPERIMENT; MALE; NONHUMAN; NORMAL HUMAN; OBESITY; RAT; SEX DIFFERENCE;

ADIPOSE TISSUE; ANIMAL; BODY COMPOSITION; CREATININE; KIDNEY; MALE; METABOLIC CLEARANCE RATE; OBESITY; RATS; RATS, INBRED STRAINS; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0023943265     PISSN: 00029343     EISSN: None     Source Type: Journal    
DOI: 10.1016/0002-9343(88)90310-5     Document Type: Article

References (36)

1. Drug dosage in patients with renal disease
2. Pharmacokinetics in renal disease
3. Clinical estimation of creatinine clearance
4. Estimating creatinine clearance in morbidly obese patients
5. Drug disposition in obese humans—an update
6. An overfed rat model that reproduces acetaminophen disposition in obese humans
7. Dietary obesity in rats: body weight and body fat accretion in seven strains of rats
8. In vivo determination of body composition by tritium dilution in the rat
9. Pharmacokinetics of tritiated water in normal and dietary-induced obese rats
10. Determination of serum creatinine by a direct colormetric method
11. 2) as a measure of fatness
12. Rapid evaluation of creatinine clearance
13. Prediction of creatinine clearance from serum creatinine
14. A computer program for estimation of creatinine clearance from unstable serum creatinine levels, age, sex, and weight
15. Vancomycin pharmacokinetics in normal and morbidly obese subjects
16. Cimetidine clearance in the obese
17. Fitting straight lines when both variables are subject to error
18. Influence of weight on aminoglycoside pharmacokinetics in normal weight and morbidly obese patients
19. Lean body mass in obesity
20. Theophylline tissue partitioning and volume of distribution in normal and dietary-induced obese rats
21. Increased glomerular filtration rate and adrenocortical function in obese women
22. The sizes and numbers of cells in visceral organs in human obesity
23. Renal function in the obese Zucker rat
24. Effects of genetic obesity on renal structure and function in the Zucker rat
25. Effects of genetic obesity on renal structure and function in the Zucker rat. II. Micropuncture studies
26. Heat loss and energy retention during growth in congenitally obese and lean rats
27. The relationship of body composition to oxygen consumption and creatinine excretion in healthy and wasted men
28. Creatinine excretion and body composition
29. Health Implications of Obesity
30. Anesthetic biotransformation and renal function in obese patients during and after methoxyflurane or halothane anesthesia
31. Obesity as a risk factor in drug-induced organ injury: increased liver and kidney damage by acetaminophen in the obese overfed rat
32. A controlled investigation of the pharmacokinetics of gentamicin and tobramycin in obese subjects
33. Effect of obesity on gentamicin pharmacokinetics
34. Amikacin pharmacokinetics in morbidly obese patients undergoing gastric-bypass surgery
35. Digoxin disposition in obesity: clinical pharmacokinetic investigation