Middle cerebral artery thrombosis: Acute blood-brain barrier consequences

Journal of Neuropathology and Experimental Neurology

Volumn 47, Issue 4, 1988, Pages 443-451

  Dietrich, W Dalton ^a   Prado, Ricardo ^a   Watson, Brant D ^a   Nakayama, Hitoshi ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

Blood brain barrier; Middle cerebral artery; Thrombosis

Indexed keywords

ANIMAL EXPERIMENT; BLOOD BRAIN BARRIER; HISTOLOGY; MAMMAL; MIDDLE CEREBRAL ARTERY; NONHUMAN; OCCLUSIVE CEREBROVASCULAR DISEASE; RAT; ULTRASTRUCTURE;

ANIMAL; BLOOD-BRAIN BARRIER; CEREBRAL ARTERIES; CONSTRICTION, PATHOLOGIC; INTRACRANIAL EMBOLISM AND THROMBOSIS; MICROSCOPY, ELECTRON; MICROSCOPY, ELECTRON, SCANNING; RADIATION INJURIES, EXPERIMENTAL; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TIME FACTORS;

EID: 0023927667     PISSN: 00223069     EISSN: 15546578     Source Type: Journal    
DOI: 10.1097/00005072-198807000-00005     Document Type: Article

References (34)

1. Garcia JH, Cox JV, Hudgins WR. Ultrastructure of the microvasculature in experimental cerebral infarction. Acta Neuropathol (Berl) 1971;18:273–85
2. 125I-albumin. Stroke 1985;16:101–9
3. Hossmann K.-A, Schuier FJ. Experimental brain infarcts in cats. I. Pathophysiological observations. Stroke 1980;11:583–92
4. Olsson Y, Crowell RM, Klatzo I. The blood-brain barrier to protein tracers in focal cerebral ischemia and infarction caused by occlusion of the middle cerebral artery. Acta Neuropathol (Berl) 1971; 18: 89–102
5. Tamura A, Asano T, Sano K. Correlation between rCBF and histological changes following temporary middle cerebral artery occlusion. Stroke 1980; 11:487–93
6. Tamura A, Graham DI, McCulloch J, Teasdale GM. Focal cerebral ischaemia in the rat. 1. Description of technique and early neuropathological consequences following middle cerebral artery occlusion. J Cereb Blood Flow Metab 1981;1:53–60
7. Gotoh O, Mohamed AA, McCulloch J, Graham DI, Harper AM, Teasdale GM. Nimodipine and the haemodynamic and histopathological consequences of middle cerebral artery occlusion in the rat. J Cereb Blood Flow Metab 1986;6:321–31
8. Nedergaard M, Gjedde A, Diemer NH. Focal ischemia of the rat brain: Autoradiographic determination of cerebral glucose utilization, glucose content, and blood flow. J Cereb Blood Flow Metab 1986;6:414–24
9. l4C)iodoantipyrine autoradiography following middle cerebral artery occlusion. J Cereb Blood Flow Metab 1981;1:61–9
10. Tyson GW, Teasdale GM, Graham DI, McCulloch J. Focal cerebral ischemia in the rat. Topography of hemodynamic and histopathological changes. Ann Neurol 1984;15:559–67
11. Yamaguchi T, Waltz AG, Okazaki H. Hyperemia and ischemia in experimental cerebral infarction: Correlations of histopathology and regional blood flow. Neurology 1971;21:565–78
12. Dietrich WD, Ginsberg MD, Busto R, Watson BD. Photochemically induced cortical infarction in the rat: 1. Time course of hemodynamic consequences. J Cereb Blood Flow Metab 1986;6:184–94
13. Dietrich WD, Watson BD, Busto R, Ginsberg MD, Bethea JR. Photochemically induced cerebral infarction: I. Early microvascular alterations. Acta Neuropathol (Berl) 1987;72:315–25
14. Dietrich WD, Busto R, Watson BD, Scheinberg P, Ginsberg MD. Photochemically induced cerebral infarction: II. Edema and blood-brain barrier disruption. Acta Neuropathol (Berl) 1987;72:326–34
15. Watson BD, Dietrich WD, Busto R, Wachtel MS, Ginsberg MD. Induction of reproducible brain infarction by photochemically initiated thrombosis. Ann Neurol 1985;17:497–504
16. Watson BD, Dietrich WD, Prado R, Ginsberg MD. Argon laser-induced arterial photothrombosis: Characterization and possible application to therapy of arteriovenous malformations. J Neurosurg 1987;66:748–54
17. Nakayama H, Dietrich WD, Watson BD, Prado R, Busto R, Ginsberg MD. Pharmacologically induced recirculation following experimental middle cerebral artery thrombosis: Histopathological consequences. (Abstract) J Cereb Blood Flow Metab 1987;7(Suppl. 1):S23
18. Cotran RS, Kamovsky MJ. Vascular leakage induced by horseradish peroxidase in the rat. Proc Soc Exp Biol Med 1967;126:557–61
19. Dietrich WD, Wei EP, Povlishock JT, Kontos HA. Method for the morphophysiological study of specific pial microvessels. Am J Physiol 1980;238:H172–5
20. Dietrich WD, Busto R, Ginsberg MD. Cerebral endothelial microvilli: Formation following global forebrain ischemia. J Neuropathol Exp Neurol 1984;43:72–83
21. Itoh K, Konishi A, Nomura S, Mizuno N, Nakamura Y, Sugimoto T. Application of coupled oxidation reaction to electron microscopic demonstration of horseradish peroxidase: Cobalt-glucose oxidase method. Brain Res 1970;175:341–6
22. Hossmann K-A, Olsson Y. The effect of transient cerebral ischemia on the vascular permeability to protein tracers. Acta Neuropathol (Berl) 1971;18:103–12
23. Petito CK, Pulsinelli WA, Jacobson G, Plum F. Edema and vascular permeability in cerebral ischemia: Comparison between ischemic neuronal damage and infarction. J Neuropathol Exp Neurol 1982;41: 423–36
24. Tyson GW, Teasdale GM, Graham DI, McCulloch J. Cerebrovascular permeability following MCA occlusion in the rat. The effect of halothane-induced hypotension. J Neurosurg 1982;57:186–96
25. Kogure K, Busto R, Scheinberg P, Reinmuth OM. Energy metabolites and water content in rat brain during the early stage of development of cerebral infarction. Brain 1974;97:103–14
26. Schuier FJ, Vise WM, Hossmann KA, Zulch KJ. Cerebral microembolization. II. Morphological studies. Arch Neurol 1978;35:264–70
27. Osterholm JL, Pyenson J. Experimental effects of free serotonin on the brain and its relation to brain injury. Part 3: Serotonin-induced cerebral edema. J Neurosurg 1969;31:417–21
28. Westergaard E. Enhanced vesicular transport of exogenous peroxidase across cerebral vessels induced by serotonin. Acta Neuropathol (Berl) 1975;32:27–42
29. Olesen S-P. A calcium-dependent reversible permeability increase in microvessels in frog brain, induced by serotonin. J Physiol 1985;361:103–13
30. 2. Science 1980;209:1242–5
31. Wei EP, Kontos HA, Dietrich WD, Povlishock JT, Ellis EF. Inhibition by free radical scavengers and cyclooxygenase inhibitors of pial arteriolar abnormalities from concussive brain injury in cats. Circ Res 1981;48:95–103
32. Del Maestro RF. Role of superoxide anion radicals in microvascular permeability and leukocyte behavior. Can J Physiol Pharmacol 1982;60:1406–14
33. Ley K, Arfors K-E. Changes in the macromolecular permeability by intravascular generation of oxygen-derived free radicals. Microvasc Res 1982;24:25–33
34. Chan PH, Schmidley JW, Fishman RA, Longar SM. Brain injury, edema, and vascular permeability changes induced by oxygen-derived free radicals. Neurology 1984;34:315–20