Direct inhibition of collagen production in vitro by diabetic rat serum

Metabolism

Volumn 37, Issue 5, 1988, Pages 479-485

  Spanheimer, Robert G ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; CARTILAGE; DIABETES MELLITUS; HYPOPHYSECTOMY; NONHUMAN; PRIORITY JOURNAL; RAT;

3-HYDROXYBUTYRIC ACID; ANIMAL; CARTILAGE; COLLAGEN; DIABETES MELLITUS, EXPERIMENTAL; DNA; GLUCOSE; HYDROXYBUTYRATES; HYPOPHYSECTOMY; IN VITRO; INSULIN; MALE; MOLECULAR WEIGHT; PROTEINS; RATS; RATS, INBRED STRAINS; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0023926077     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1016/0026-0495(88)90050-9     Document Type: Article

References (20)

1. Accelerated age-related browning of human collagen in diabetes mellitus
2. Apparent accelerated aging of human collagen in diabetes mellitus
3. A specific decrease in collagen synthesis in acutely fasted, vitamin C-supplemented, guinea pigs
4. Specifically decreased collagen biosynthesis in scurvy dissociated from an effect on proline hydroxylation and correlated with body weight loss
5. Abnormalities in proliferation and protein synthesis in skin fibroblast cultures from patients with diabetes mellitus
6. Arterial procollagen type I and type III, and fibronectin. Effects of diabetic serum, glucose, insulin, ketone, and growth hormone studied on rabbit aortic myomedial cell cultures
7. Sera from type 2 (non-insulin-dependent) diabetic and healthy subjects contain different amounts of a very low molecular weight growth peptide for vascular cells
8. The effect of streptozotocin-induced diabetes mellitus on the ability of rat serum to stimulate human fibroblast proliferation
9. Nutrition and somatomedin. VIII. The somatomedin inhibitor in diabetic rat serum is a general inhibitor of growing cartilage
10. 14 to labeled hydroxyproline by rat cartilage in vitro: Effects of hypophysectomy, growth hormone, and cortisol
11. Nutrition and somatomedin. I. Effect of fasting and refeeding on serum somatomedin activity and cartilage growth activity in rats
12. Use of a mixture of proteinase-free collagenase for the specific assay of radioactive collagen in the presence of other proteins
13. Determination of collagen synthesis in tissue and cell culture systems
14. Fluorimetric determination of DNA in papain digests of cartilage, using ethidium bromide
15. Growth and maturation of children with insulin-dependent diabetes mellitus
16. Wound healing and the diabetic patient
17. Decreased corticol thickness and osteopenia in children with diabetes mellitus
18. The chemistry and biology of collagen
19. Characterization of the effect of insulin on collagen synthesis in fetal rat bone
20. The anabolic effect of insulin on type II collagen synthesis of Swarm rat chondrosarcoma chondrocytes