Risk of dementia in relatives of patients with Alzheimer’s disease

Neurology

Volumn 38, Issue 5, 1988, Pages 786-790

  Huff, F Jacob ^a   Auerbach, Jonathan ^a   Chakravarti, Aravinda ^a   Boller, François ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ALZHEIMER DISEASE; CLINICAL ARTICLE; DEMENTIA; FEMALE; HEREDITY; HUMAN; MALE; METHODOLOGY; PRIORITY JOURNAL; QUESTIONNAIRE;

ACTUARIAL ANALYSIS; AGE FACTORS; AGED; ALZHEIMER DISEASE; FEMALE; HUMAN; MALE; MIDDLE AGE; QUESTIONNAIRES; RISK FACTORS; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0023914811     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/wnl.38.5.786     Document Type: Article

References (39)

1. Heston L, White J. Pedigrees of 30 families with Alzheimer’s disease: associations with defective organization of microfilaments and microtubules. Behav Genet 1978;8:315-331.
2. Cook R, Ward B, Austin J. Studies in aging of the brain. V. Familial Alzheimer disease. Neurology 1979;29:1402–1412.
3. Masters C, Gajdusek C, Gibbs C Jr. The familial Occurrence of Creutzfeldt-Jakob disease and Alzheimer’s disease. Brain 1981;104:535–558.
4. Goudsmit J, White BJ, Weitkamp LR, et al. Familial Alzheimer’s disease in two kindreds of the same geographic and ethnic origin: a clinical and genetic study. J Neurol Sci 1981;49:79–89.
5. Nee LE, Polinsky RJ, Eldridge R, Weingartner H, Smallberg S, Ebert M. A family with histologically confirmed Alzheimer’s disease. Arch Neurol 1983;40:203–208.
6. Foncin J, Salmon D, Supino-Viterbo V, et al. DCmence présénile d’Alzheimer transmise dans une famille Ctendue. Rev Neurol (Paris) 1985;141:194–202.
7. Schellenberg GD, Deeb SS, Boehnke M, et al. Association of an apolipoprotein CII allele with familial dementia of the Alzheimer type. J Neurogenet 1987;4:97–108.
8. Sjogren T, Sjogren H, Lundgren G. Morbus Alzheimer and morbus Pick. Acta Pychiatr Neurol Scand [Suppl] 1952;82:9–51.
9. Larsson T, Sjogren T, Jacobsen G. Senile dementia: a clinical sociomedical and genetic study. Acta Psychiatr Scand Suppl 1963;39:1–259.
10. Heston L, Mastri A, Anderson E, White J. Dementia of the Alzheimer type. Arch Gen Psychiatry 1981;38:1085–1090.
11. Breitner J, Folstein M. Familial Alzheimer dementia: a prevalent disorder with specific clinical features. Psychol Med 1984;14:63–80.
12. Mohs RC, Breitner JCS, Silverman JM, Davis KL. Alzheimer’s disease: morbid risk among first-degree relatives approximates 50% by 90 years of age. Arch Gen Psychiatry 1987;44:405–408.
13. Breitner JCS, Silverman JM, Mohs RC, Davis KL. Familial aggregation in Alzheimer’s disease: comparison of risk among relatives of early- and late-onset cases, and among male and female relatives in successive generations. Neurology 1988;38:207–212.
14. Chase GA, Folstein MF, Breitner JCS, Beaty TH, Self SG. The use of life tables and survival analysis in testing genetic hypotheses, with an application to Alzheimer’s disease. Am J Epidemiol 1983;117:590–597.
15. Breitner JCS, Folstein MF, Murphy EA. Familial aggregation in Alzheimer dementia. I. A model for the age-dependent expression of an autosomal dominant gene. J Psychiatr Res 1986;20:31–43.
16. McKhann G, Drachman D, Folstein M, et al. Clinical diagnosis of Alzheimer’s disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer’s Disease. Neurology 1984;34:939–944.
17. Huff FJ, Becker JT, Belle SH, Nebes RD, Holland AL, Boller F. Cognitive deficits and clinical diagnosis of Alzheimer’s disease. Neurology 1987;37:1119–1124.
18. Martin EM, Wilson RS, Penn RD, Fox JH, Clasen RA, Savoy SM. Cortical biopsy results in Alzheimer’s disease: correlation with cognitive deficits. Neurology 1987;37:1201–1204.
19. Khachaturian ZS. Diagnosis of Alzheimer’s disease. Arch Neurol 1985;42:1097–1105.
20. Heyman A, Wilkinson WE, Hurwitz BJ, et al. Alzheimer’s disease: genetic aspects and associated clinical disorders. Ann Neurol 1983;14:507–515.
21. Kaplan EL, Meier P. Non-parametric estimation from incomplete observations. J Am Stat Aseoc 1958;53:457–481.
22. Benedetti J, Yuen K, Young L. Life tables and survival functions. In: Dixon WJ, ed. BMDP statistical software. Berkeley, CA: University of California Press, 1985:557–575.
23. Rocca WA, Amaducci LA, Schoenberg BS. Epidemiology of clinically diagnosed Alzheimer’s disease. Ann Neurol 1986;19:415–424.
24. Selzer B, Sherwin I. A comparison of clinical features in early- and late-onset primary degenerative dementia: one entity or two? Arch Neurol 1983;40:143–146.
25. Huff FJ, Growdon JH, Corkin S, Rosen TJ. Age at onset and rate of progression of Alzheimer’s disease. J Am Geriatr Soc 1987;35:27–30.
26. Amaducci LA, Fratiglioni L, Rocca WA, et al. Risk factors for clinically diagnosed Alzheimer’s disease: a case-control study of an Italian population. Neurology 1986;36:922–931.
27. Silverman JM, Breitner JCS, Mohs RC, Davis KL. Reliability of the family history method in genetic studies of Alzheimer’s disease and related dementias. Am J Psychiatry 1986;143:1279–1282.
28. Akesson HO. A population study of senile and arteriosclerotic psychoses. Hum Hered 1969 19:546–565.
29. Powell D, Folstein MF. Pedigree study of familial Alzheimer disease. J Neurogenet 1984;1:189–197.
30. Heyman A, Wilkinson WE, Stafford JA, Helms MJ, Sigmon AH, Weinberg T. Alzheimer’s disease: a study of epidemiologic aspects. Ann Neurol 1984;15:335–341.
31. French LR, Schuman LM, Mortimer JA, et al. A case control study of dementia of the Alzheimer type. Am J Epidemiol 1985;121:414–421.
32. Whalley LJ, Carothers AD, Collyer S, DeMay R, Frackiewicz A. A study of familial factors in Alzheimer’s disease. Br J Psychiatry 1982;140:249–256.
33. St George-Hyslop PH, Tanzi RE, Polinsky RJ, et al. The genetic defect causing familial Alzheimer’s disease maps on chromoeome 21. Science 1987;235:885–890.
34. Delabar JM, Goldgaber D, Lamour Y, et al. Beta amyloid gene duplication in Alzheimer’s disease and karyotypically normal Down syndrome. Science 1987;235:1390–1392.
35. Heston LL, White JA, Mastri AR. Pick’s disease: clinical genetics and natural history. Arch Gen Psychiatry 1987;44:409–411.
36. Moossy J, Martinez J, Hanin I, Rao G, Yonas H, Boller F. Thalamic and subcortical gliosis with dementia. Arch Neurol 1987;44:510–513.
37. Kim RC, Collins GH, Parisi JE, Wright AW, Chu YB. Familial dementia of adult onset with pathological findings of a “nonspecific” nature. Brain 1981;104:61–78.
38. Morris JC, Cole M, Banker BQ, Wright D. Hereditary dysphasic dementia and the Pick-Alzheimer spectrum. Ann Neurol 1984;16:455–466.
39. Goldgaber D, Lerman MI, McBride OW, Saffiotti V, Gajdwk DC. Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer’s disease. Science 1987;235:877–880.