Prevention of Skin Cancer in Xeroderma Pigmentosum with the Use of Oral Isotretinoin

New England Journal of Medicine

Volumn 318, Issue 25, 1988, Pages 1633-1637

  Kraemer, Kenneth H ^a   Digiovanna, John J ^b   Moshell, Alan N ^c   Tarone, Robert E ^d   Peck, Gary L ^b  

^a NCl   (United States)

^b Dermatology Branch   (United States)

^c NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^d NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ISOTRETINOIN;

ADOLESCENT; ADULT; ARTHRALGIA; CALCIFYING TENDINITIS; CLINICAL ARTICLE; DRY EYE; DRY SKIN; FEMALE; HUMAN; HYPERTRIGLYCERIDEMIA; HYPOPIGMENTATION; LIGAMENT CALCINOSIS; LIVER FUNCTION; MALE; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; SCHOOL CHILD; SKIN CANCER; XERODERMA PIGMENTOSUM;

EID: 0023911552     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJM198806233182501     Document Type: Article

References (24)

1. Scotto J, Fears TR, Fraumeni JF Jr. Incidence of nonmelanoma skin cancer in the United States. Bethesda, Md.: Department of Health and Human Services, 1981. (DHHS publication no. (NIH) 82–2433.)
2. Kraemer KH, Slor H. Xeroderma pigmentosum. Clin Dermatol 1985; 3: 33–69.
3. Kraemer KH, Lee MM, Scotto J. Xeroderma pigmentosum: cutaneous, ocular, and neurologic abnormalities in 830 published cases. Arch Dermatol 1987; 123: 241–50.
4. Kraemer KH, Lee MM, Scotto J. DNA repair protects against cutaneous and internal neoplasia: evidence from xeroderma pigmentosum. Carcinogenesis 1984; 5: 511–4.
5. Bertram JS, Kolonel LN, Meyskens FL Jr. Rationale and strategies for chemoprevention of cancer in humans. Cancer Res 1987; 47: 3012–31.
6. Lippman SM, Kessler JF, Meyskens FL Jr. Retinoids as preventive and therapeutic anticancer agents (Part I). Cancer Treat Rep 1987; 71: 391–405.
7. Lippman Retinoids as preventive and therapeutic anticancer agents (Part II). Cancer Treat Rep 1987; 71: 493–515.
8. Moon RC, Itri LM. Retinoids and cancer. In: Sporn MB, Roberts AB, Goodman DS, eds. The retinoids. Vol. 2. New York: Academic Press, 1984:327–71.
9. Hong WK, Endicott J, Itri LM, et al. 13-cis-Retinoic acid in the treatment of oral leukoplakia. N Engl J Med 1986; 315: 1501–5.
10. Clark RE, Jacobs A, Lush CJ, Smith SA. Effect of 13-cis-retinoic acid on survival of patients with myelodysplastic syndrome. Lancet 1987; 1: 763–5.
11. Peck GL, Yoder FW, Olsen TG, Pandya MD, Butkus D. Treatment of Darier's disease, lamellar ichthyosis, pityriasis rubra pilaris, cystic acne, and basal cell carcinoma with oral 13-cis-retinoic acid. Dermatologica 1978; 157: Suppl 1: 11–2.
12. Peck GL, Olsen TG, Butkus D, et al. Treatment of basal cell carcinomas with 13-cis-retinoic acid. Proc Am Assoc Cancer Res 1979; 20: 56. abstract.
13. Schnitzler L, Schubert B, Verret J-L. Essai de prèvention des épithéliomas cutanés par le rétinoïde aromatique. Ann Dermatol Venereol 1980; 107: 657–63.
14. Braun-Falco O, Galosi A, Dorn M, Plewig G. Tumorprophylaxe bei Xeroderma pigmentosum mit aromatischem Retinoid (Ro 10–9359). Hautarzt 1982; 33: 445–8.
15. Peck GL, Gross EG, Butkus D, DiGiovanna JJ. Chemoprevention of basal cell carcinoma with isotretinoin. J Am Acad Dermatol 1982; 6: 815–23.
16. Claudy A-L, Soulas G, Lauras B, Freycon M-T, Le Petit J-C, Fraisse J. Xeroderma pigmentosum et traitement au long cours par le rétinoide aromatique: action préventive sur les dégénérescences épithéliomateuses? Ann Dermatol Venereol 1982; 109: 271–4.
17. Meyskens FL Jr, Gilmartin E, Alberts DS, et al. Activity of isotretinoin against squamous cell cancers and preneoplastic lesions. Cancer Treat Rep 1982; 66: 1315–9.
18. Cristofolini M, Zumaiani G, Scappini P, Pisciolo F. Aromatic retinoid in the chemoprevention of the progression of nevoid basal-cell carcinoma syndrome. J Dermatol Surg Oncol 1984; 10: 778–81.
19. Berretti B, Grupper C. Cutaneous neoplasia and etretinate. In: Cunliffe WJ, Miller AJ, eds. Retinoid therapy. Lancaster, England: MTP Press, 1984:187–94.
20. Peck GL. Long-term retinoid therapy is needed for maintenance of cancer chemopreventive effect. Dermatologica 1987; 175: Suppl 1: 138–44.
21. Yuspa SH. Cutaneous chemical carcinogenesis. J Am Acad Dermatol 1986; 15: 1031–44.
22. Thiele CJ, Reynolds CP, Israel MA. Decreased expression of N-myc precedes retinoic acid-induced morphological differentiation of human neuroblastoma. Nature 1985; 313: 404–6.
23. van Voorst Vader PC, Jaspers NGJ, van der Kamp AWM. Retinoic acid and defective UV light induced DNA excision repair in xeroderma pigmentosum: absence of ameliorating effect. Arch Dermatol Res 1984; 276: 201–2.
24. DiGiovanna JJ, Helfgott RK. Gerber LH, Peck GL. Extraspinal tendon and ligament calcification associated with long-term therapy with etretinate. N Engl J Med 1986; 315: 1177–82.