Signal transduction in cells following binding of chemoattractants to membrane receptors

Virchows Archiv B: Cell Pathology

Volumn 55, Issue 1, 1988, Pages 65-80

  Dillon, Susan B ^a,b   Verghese, Margrith W ^a,c   Snyderman, Ralph ^a,d  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b GLAXOSMITHKLINE   (United Kingdom)

^c GLAXOSMITHKLINE   (United States)

^d GENENTECH INC   (United States)

Author keywords

Chemoattractant receptors; Guanine nucleotide regulatory proteins; Phosphoinositides; Protein kinase C; Signal transduction

Indexed keywords

CELL SURFACE RECEPTOR; CHEMOATTRACTANT; GUANINE NUCLEOTIDE BINDING PROTEIN; PHOSPHATIDYLINOSITIDE; PHOSPHOLIPASE C; PROTEIN KINASE C;

CELL MIGRATION; CHEMOTAXIS; HUMAN; HUMAN CELL; NORMAL HUMAN; SIGNAL TRANSDUCTION;

CELL MOVEMENT; CHEMOTACTIC FACTORS; CYTOTOXINS; GTP-BINDING PROTEINS; HUMAN; MODELS, BIOLOGICAL; N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE; NEUTROPHILS; PHAGOCYTOSIS; PHOSPHOLIPASE C; PROTEIN KINASE C; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0023911415     PISSN: 03406075     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02896561     Document Type: Review

References (146)

1. Calcium-mobilizing receptors, polyphosphoinositides, and the generation of second messengers
2. 2+ mobilization
3. Pertussis toxin inhibition of chemotaxis and the ADP-ribosylation of a membrane protein in a human-mouse hybrid cell line
4. The metabolism of inositol 1,3,4-trisphosphate to inositol 1,3-bisphosphate
5. Two roles for guanine nucleotides in the stimulus-secretion sequence of neutrophils
6. Priming of the respiratory burst of neutrophils by diacylglycerol: Independence from activation or translocation of protein kinase C
7. Protein kinase C activation by diacylglycerol second messengers
8. β-adrenergic receptor kinase: Identification of a novel protein kinase that phosphorylates the agonist-occupied form of the receptor
9. Inositol trisphosphate and diacylglycerol as second messengers
10. Inositol trisphosphate, a novel second messenger in cellular signal transduction
11. Rapid formation of diacylglycerol from phosphatidylcholine: a pathway for generation of a second messenger
12. Calciumcalmodulin stimulates inositol 1,4,5-trisphosphate kinase activity from insulin-secreting RINm5F cells
13. Regulation of hormone receptors and adenylyl cyclases by guanine nucleotide binding N proteins
14. Inhibition of receptor-mediated release of arachidonic acid by pertussis toxin
15. Quantitative changes in inositol 1,4,5-trisphosphate in chemoattractant-stimulated neutrophils
16. Pertussis toxin inhibits chemotactic peptide-stimulated generation of inositol phosphates and lysosomal enzyme secretion in human leukemic (HL-60) cells
17. 1adrenergic stimulation in FRTL5 cells
18. Stimulus-secretion coupling in rabbit neutrophils is not mediated by phosphatidylinositol breakdown
19. Role of guanine nucleotide binding protein in the activation of polyphosphoinositide phosphodiesterase
20. p
21. Protein kinase C phosphorylates human platelet inositol trisphosphate 5−phosphomonoesterase, increasing the phosphatase activity
22. The metabolism of trisand tetraphosphates of inositol by 5-phosphomonoesterase and 3-kinase enzymes
23. Coussens L, Parker PJ, Rhee L, Yang-Feng TL, Chen E, Water-field MD, Francke U, Ullrich A (1986) Multiple, distinct forms of bovine and human protein kinase C suggest diversity in cellular signaling pathways. Science pp 859–866
24. Differential stimulation of the respiratory burst and lysosomal enzyme in polymorphlnuclear leukocytes by synthetic diacylglycerols
25. Comparison of subcellular activation of the human neutrophil NADPH-oxidase by arachidonic acid, sodium dodecyl sulfate (SDS), and phorbol myristate acetate (PMA)
26. Activation of human neutrophil nicotinamide adenine dinucleotide phosphate, reduced (triphosphopyridine nucleotide, reduced) oxidase by arachidonic acid in a cell-free system
27. Phorbol 12, myristate 13, acetate potentiates the respiratory burst while inhibits phosphoinositide hydrolysis and calcium mobilization by formyl-methionyl-leucyl-phenylalanine in human neutrophils
28. i protein alpha-subunit: deduction of amino acid structure from a cloned cDNA
29. Molecular cloning of a novel human GTP-binding protein and its potential role in chemoattractant stimulus-response coupling
30. Identification of a novel inositol bisphosphate isomer formed in chemoattractant stimulated human polymorphonuclear leukocytes
31. Regulation of inositol phosphate metabolism in chemoattractant-stimulated human polymorphonuclear leukocytes
32. Regulation of inositol phospholipid and inositol phosphate metabolism in chemoattractant-activated human polymorphonuclear leukocytes
33. 2+ concentration
34. Secretagogue-induced phosphoinositide metabolism in human leukocytes
35. Relationship of phosphatidylinositol bisphosphate hydrolysis to calcium mobilization and functional activation in fluoride-treated neutrophils
36. 4 chemotaxis receptors
37. Degranulating stimuli increase the availability of receptors on human neutrophils for the chemoattractant fMet-Leu-Phe
38. Human neutrophils contain an intracellular pool of putative receptors for the chemoattractant N-formyl methionylleucylphenylalanine with a density of specific granules
39. Diacylglycerol; 1-oleoyl-2-acetylglycerol, stimulates Superoxide generation from human neutrophils
40. Regulation of neutrophil NADPH oxidase activation in a cell-free system by guanine nucleotides and fluoride
41. Characterization of the formyl peptide chemotactic receptor appearing at the phagocytic cell surface after exposure to phorbol myristate acetate
42. Role of protein kinases in stimulation of human polymorphonuclear leukocyte oxidative metabolism by various agents
43. Immunochemical evidence for a novel pertussis toxin substrate in human neutrophils
44. G Proteins: Transducers of receptor-generated signals
45. Pertussis toxin inhibition of chemotactic factorinduced calcium mobilization and function in human polymorphonuclear leukocytes
46. 4
47. The effects of lithium ion and other agents on the activity of myo-inositol-1-phosphatase from bovine brain
48. Inhibition of human neutrophil chemotaxis by the protein kinase inhibitor, l-(5-isoquinolinesulfonyl) piperazine
49. Chemoattractantinduced activation of c-fos gene expression in human monocytes
50. Cytochalasin B enhancement of the diacylglycerol response in formyl peptide-stimulated neutrophils
51. Regulation of inositol 1,4,5-trisphosphate kinase activity after stimulation of human T cell antigen receptor
52. Pathway for inositol 1,3,4-trisphosphate and 1,4-bisphosphate metabolism
53. Inositol trisphosphates in carbachol-stimulated rat parotid glands
54. 2+
55. 2+ mobilization from Swiss-mouse 3T3 cells
56. 3 3-kinase activity in animal tissues
57. Inositol (1,3,4,5) tetrakisphosphate-induced activation of sea urchin eggs requires the presence of inositol trisphosphate
58. Phosphatidylcholine breakdown in rat liver plasma membranes
59. Molecular cloning of five GTPbinding protein cDNA species from rat olfactory neuroepithelium
60. Induction of selective biological responses to chemoattractants in a human monocyte-like cell line
61. Direct evidence for involvement of a guanine nucleotide-binding protein in chemotactic peptide-stimulated formation of inositol bisphosphate and trisphosphate in differentiated human leukemic (HL-60) cells
62. Modes of inhibitory action of protein kinase C in the chemotactic peptide-induced formation of inositol phosphates in differentiated human leukemic (HL-60) cells
63. Proteolytic activation of calcium-activated, phospholipid-dependent protein kinase by calcium-dependent neutral protease
64. Cloning and expression of multiple protein kinase C c-DNA’s
65. Stimulus response coupling in the human neutrophil
66. Stimulus response coupling in the human neutrophil
67. The oligopeptide chemotactic factor receptor on human polymorphonuclear leukocyte membranes exists in two affinity states
68. Guanine nucleotides modulate the binding affinity of the oligopeptide chemoattractant receptor on human polymorphonuclear leukocytes
69. Chemotactic peptide activation of human neutrophils and HL-60 cells
70. 2+ pumping sites in human neutrophils
71. A pertussis toxin-sensitive GTP-binding protein in the human neutrophil regulates multiple receptors, calcium mobilization, and lectin-induced capping
72. Stimulation of neutrophil oxidative metabolism by chemotactic peptides: Influence of calcium ion concentration and cytochalosin B and comparison with stimulation by phorbol myristate acetate
73. Quantitative analysis of the cytosolic free calcium dependency of exocytosis from three subcellular compartments in intact human neutrophils
74. The role of cytosolic free calcium in the generation of inositol 1,4,5-trisphosphate and inositol 1,3,4-trisphosphate in HL-60 cells
75. Amphotericin B alters the affinity and functional activity of the oligopeptide chemotactic factor receptor in human polymorphonuclear leukocytes
76. 2+-dependent protein kinase
77. Mechanisms of regulating the respiratory burst in leukocytes
78. The NADPH oxidase of human polymorphonuclear leukocytes
79. Activation of the respiratory burst enzyme from human neutrophils in a cell-free system
80. The metabolism of phosphoinositide-derived messenger molecules
81. Asparagine-linked oligosaccharides on formyl peptide chemotactic receptors of human phagocytic cells
82. G-protein dissociation, GTP-GDP exchange and GTPase activity in control and PMA treated neutrophils stimulated by fMet-Leu-Phe
83. 2+-requiring proteinase
84. The involvement of calpain in the activation of protein kinase C in neutrophils stimulated by phorbol muristic acid
85. Phorbol 12,13-dibutyrate and 1-oleyl-2-acetyldiacylglycerol stimulate inositol trisphosphate dephosphorylation in human platelets
86. Pertussis toxin inhibits the rise in the intracellular concentration of free calcium that is induced by chemotactic factors in rabbit neutrophils: Possible role of the “G proteins” in calcium mobilization
87. i in HL60 cells
88. Evidence for subcellular redistribution of 5-lipoxygenase during human neutrophil activation by phlogistic stimuli
89. Redistribution of protein kinase C activity in human monocytes: correlation with activation of the respiratory burst
90. 4 stimulated calcium mobilization and enzyme secretion in rabbit neutrophils
91. The role of protein kinase C in cell surface signal transduction and tumour promotion
92. Turnover of inositol phospholipids and signal transduction
93. Binding and metabolism of platelet-activating factor by human neutrophils
94. Tissue-specific expression of three distinct types of rabbit protein kinase C
95. 2+ mobilization in guinea pig neutrophils
96. A new GTP-binding protein in differentiated human leukemic (HL-60) cells serving as the specific substrate of islet-activating protein, pertussis toxin
97. Coupling of the guanine nucleotide regulatory protein to chemotactic peptide receptors in neutrophil membranes and its uncoupling by isletactivating protein, pertussis toxin
98. 4-induced activation signals and responses in neutrophils are short-lived compared to formylpeptide
99. Effects of leukotrienes and SMet-Leu-Phe on oxidative metabolism of neutrophils and eosinophils
100. Chemoattractant-mediated stimulation of the respiratory burst in human polymorphonuclear leukocytes may require appearance of protein kinase activity in the cells’ particulate fraction
101. G-Protein-chemoattractant receptor interaction. Co-purification to formylpeptide receptor with a guanine nucleotide binding protein
102. The formyl peptide chemoattractant receptor copurifies with a GTP binding protein containing a distinct 40 kDci pertussin toxin substrate
103. Phosphorylation of proteins in human neutrophils activated with phorbol myristate acetate or with chemotactic factor
104. Is cytosolic ionized calcium regulating neutrophil activation?
105. Quantitative measurement of sn-1,2-diacylglycerols present in platelets, hepatocytes, and rasand sistransformed normal rat kidney cells
106. 2+ homeostasis in permeabilized human neutrophils
107. Formation and biological action of inositol 1,4,5,trisphosphate
108. Guanine nucleotides stimulate NADPH oxidase in membranes of human neutrophils
109. 4 is a complete secretogogue in human neutrophils: a kinetic analysis
110. Light-dependent phosphorylation of rhodopsin: Purification and properties of rhodopsin kinase
111. The structure-activity relations of synthetic peptides as chemotactic factors and inducers of lysosomal enzyme secretion for neutrophils
112. Signal transduction and ligand-receptor dynamics in the human neutrophil
113. Regulation of ligand-receptor dynamics by guanine nucleotides: Real-time analysis of interconverting states for the neutrophil formyl peptide receptor
114. Chemoattractant receptor-induced hydrolysis of phosphatidylinositol 4,5-bisphosphate in human polymorphonuclear leukocyte membranes
115. Receptor-coupled activation of phosphoinositide-specific phospholipase C by an N protein
116. Nucleotide regulatory protein-mediated activation of phospholipase C in human polymorphonuclear leukocytes is disrupted by phorbol esters
117. N-formylmethionyl peptide receptors on equine leukocytes initiate secretion but not chemotaxis
118. Chemoattractant receptors on phagocytic cells
119. A chemoattractant receptor on macrophages exists in two affinity states regulated by guanine nucleotides
120. Model for leukocyte regulation by chemoattractant receptors
121. Phagocytic cells: Stimulus-response coupling mechanisms
122. 32P-inositol-1,4,5-trisphosphate in hepatocytes and neutrophils
123. Signal transduction by guanine nucleotide binding proteins
124. 2+ from a nonmitochondrial intracellular store in pancreatic acinar cells by inositol-1, 4, 5-trisphosphate
125. itype subunits
126. Inhibitory effect of prostaglandin E2, forskolin, and dibutyryl cAMP on arachidonic acid release and inositol phospholipid metabolism in guinea pig neutrophils
127. A tumour promoter, 12-O-tetradecanoylphorbol 13-acetate, increases cellular diacylglycerol content through a mechanism other than phosphoinositide hydrolysis in Swiss-mouse 3T3 fibroblasts
128. Protein kinase C and the activation of the human neutrophil NADPH-oxidase
129. Electrophysiological responses to bradykinin and microinjected inositol polyphosphates in neuroblastoma cells
130. Leukocyte (PMN) activation of chemoattractants (CTX): A two phase sequential pathway mediates the respiratory burst
131. Calcium influx stimulates a new pathway for sustained diacylglycerol production in leukocytes activated by chemoattractants
132. Chemoattractant receptors and signal transduction processes
133. Isolation of GTP-binding proteins from myeloid HL-60 cells: identification of two pertussis toxin substrates
134. 2+-dependent mechanism which is independent of transmembrane activation of adenylate cyclase
135. 2+ mobilization and cellular responses by leukocytes
136. 2+ mobilization and cAMP formation in human neutrophils (PMNs)
137. 2+ mobilization, and cellular responses to chemoattractants in human monocytes
138. A pertussis/ choleratoxin-sensitive N protein may mediate chemoattractant receptor signal transduction
139. Role of a guanine nucleotide regulatory protein in the activation of phospholipase C by different chemoattractants
140. Pertussis toxin inhibits fMet-Leu-Phe but not phorbol ester-stimulated changes in rabbit neutrophils: Role of G proteins in excitation response coupling
141. Ion channels in human neutrophils activated by a rise in free cytosolic calcium concentration
142. Phorbol muristate acetate mediates redistribution of protein kinase C in human neutrophils: Potential role in the activation of the respiratory burst enzyme
143. Chemoattractant receptor functions in human polymorphonuclear leukocytes are divergently altered by membrane fluidizers