Density-dependent variations in the lipid content and metabolism of cultured human keratinocytes

Journal of Investigative Dermatology

Volumn 91, Issue 1, 1988, Pages 86-

  Williams, Mary L ^a,b,c   Rutherford, Suzanne L ^a,b,c   Ponec, Maria ^a,b,c   Hincenbergs, Mara ^a,b,c   Placzek, Donna R ^a,b,c   Elias, Peter M ^a,b,c  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

HUMAN; KERATINOCYTE; LIPID METABOLISM; PRIORITY JOURNAL;

EID: 0023910150     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1111/1523-1747.ep12463297     Document Type: Article

References (47)

1. Elias P.M. Epidermal lipids, barrier function, and desquamation J Invest Dermatol 80 1983 44 49
2. Elias P.M. Friend D.S. The permeability barrier in mammalian epidermis J Cell Biol 65 1975 180 191
3. Lavker R.S. Membrane coating granules: The fate of the discharged lamellae J Ultrastruct Res 55 1976 79 86
4. Gray G.M. Yardley H.J. Different populations of pig epidermal cells: Isolation and lipid composition J Lipid Res 16 1975 441 447
5. Elias P.M. Brown B.E. Fritsch P.O. Goerke R.J. Gray G.M. White R.J. Localization and chomposition of lipids in neonatal mouse stratum granulosum and stratum corneum J Invest Dermatol 73 1979 339 348
6. Lampe M.E. Williams M.L. Elias P.M. Human epidermal lipids: Characterization and modulations during differentiation J Lipid Res 24 1983 131 140
7. Lampe M.A. Burlingame A.L. Whitney J. Williams M.L. Brown B.E. Roitman E. Elias P.M. Human statum corneum lipids: Characterization and regional variations J Lipid Res 24 1983 120 130
8. Williams M.L. Elias P.M. Stratum corneum lipids in disorders of cornification. I. Increased cholesterol sulfate content of stratum corneum in recessive x-linked ichthyosis J Clin Invest 68 1981 1404 1414
9. Gray G.M. White R.J. Epidermal lipid liposomes: A novel non-phospholipid membrane system Biochem Soc Trans London 7 1979 1129 1131
10. Epstein E.H. Jr Williams M.L. Elias P.M. Steroid sulfatase, x-linked ichthyosis and stratum corneum cell cohesion Arch Dermatol 117 1981 761 763
11. Wertz P.W. Abraham W. Landmann L. Downing D.T. Preparation of liposomes from stratum corneum lipids J Invest Dermatol 87 1986 582 584
12. Baden H.P. The keratinocyte has become the subject of intense investigation J Invest Dermatol 82 1984 305 307
13. Ponec M. Havekes L. Kempenaar J. Vermeer B.J. Cultured human skin fibroblasts and keratinocytes: Differences in the regulation of cholesterol synthesis J Invest Dermatol 81 1983 125 130
14. Ponec M. Havekes L. Kempenaar J. Lavrijsen S. Vermeer B.J. Defective low-density lipoprotein metabolism in cultured normal, transformed and malignant keratinocytes J Invest Dermatol 83 1984 436 440
15. Ponec M. Havekes L. Kempenaar J. Lavrijsen S. Wijsman M. Boonstra J. Vermeer B.J. Calcium-mediated regulation of the low density lipoprotein receptor and intracellular cholesterol synthesis in human epidermal keratinocytes J Cell Physiol 125 1985 98 106
16. Vermeer B.J. Wijsman M.C. Mommaas-Kienhuis A.M. Ponec M. Modulation of low density lipoprotein receptor activity in squamous carcinoma cells by variation in cell density Eur J Cell Biol 300 1985 353 360
17. Williams M.L. Rutherford S.L. Grayson S. Vermeer B.J. Elias P.M. Free sterol metabolism and LDL-receptor expression as differentiation markers in cultured human keratinocytes J Cell Physiol 132 1987 428 440
18. Williams M.L. Rutherford S.L. Feingold K.R. Effects of cholesterol sulfate on lipid metabolism in cultured human keratinocytes and fibroblasts J Lipid Res 28 1987 995 997
19. Havel R.J. Eder H.A. Bragdon J.H. The distribution and chemical composition of the ultracentrifugally separated lipoproteins in human serum J Clin Invest 34 1955 13 45
20. Williams M.L. Hughes-Fulford M. Elias P.M. Inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and sterol synthesis by cholesterol sulfate in cultured fibroblasts Biochim Biophys Acta 845 1985 349 357
21. Smith R.K. Krohn R.I. Hermarson G.I. Mallia A.K. Gartner F.H. Proverzan M.D. Fujimoto E.K. Goete N.M. Olson B.J. Klenk D.C. Measurement of proteins using bicinchoninic acid Anal Biochem 150 1985 76 85
22. Labarca C. Poigen P. A simple, rapid, and sensitive DNA assay procedure Anal Biochem 102 1980 344 352
23. Mangold H.K. Malins D.C. Chromatographic analysis, isolation and characterization of ether lipids H.K. Mangold F. Paltauf Ether Lipids 1983 Academic Press New York 1 15
24. Brown B.E. Williams M.L. Elias P.M. Stratum corneum lipid abnormalities in ichthyosis: Detection by a new lipid microanalytical method Arch Dermatol 120 1984 204 209
25. Williams ML. Monger DL, Hincenbergs M. Rehfeld SJ. Grunfeld C: Neutral lipid storage disease with ichthyosis: Lipid content and metaboli m in fibroblasts. J Inher Metab (in Press)
26. Barrandon Y. Green H. Cell size as a determinant of the close-forming ability of human keratinocytes Proc Natl Acad Sci USA 82 1985 5390 5394
27. Bailey JM: Lipid metabolism in cultured cells. VI: Lipid biosynthesis in erum and synthetic growth media. Biochim Biophys Acta 125:226-236
28. Chen H.W. Role of cholesterol metabolism in cell growth Federation Proc 43 1984 126 130
29. Spector A.A. Mather S.N. Kaduce T.L. Hyman B.T. Lipid nutrition and metabolism of cultured mammalian cells Prog Lipid Res 19 1981 155 186
30. Milstone I.M. Population dynamics in cultures of stratified squamous epithelia J Invest Dermatol 81 1983 695 745
31. Ponec M. Kempenaar J. Boonstra J. Regulation of lipid synthesis in relation to keratinocyte differentiation capacity Biochim Biophys Acta 92 1987 512 521
32. Madison K.C. Wertz P.W. Strauss J.S. Downing D.T. Lipid composition of cultured murine keratinocytes J Invest Dermatol 87 1986 253 259
33. Holbrook K.A. Hennings H. Phenotypic expression of epidermal cells in vitro: A review J Invest Dermatol 81 1983 11 24
34. Wertz P.W. Downing P.T. Freinkel R.K. Traczyk T.N. Sphingolipids of the stratum corneum and lamellar granules of fetal rat epidermis J Invest Dermatol 83 1984 193 195
35. Grayson S. Johnson-Winegar A.G. Wintroub B.U. Epstein E.H. Jr Elias P.M. Lamellar body-enriched fractions from neonatal mice: preparative techniques and partial characterization J Invest Dermatol 85 1985 289 295
36. Rearick J.I. Jetten A.M. Accumulation of cholesterol 3-sulfate during in vitro squamous differentiation of rabbit treated epithelial cells and its reguation by retinoids J Biol Chem 261 1986 13898 13904
37. Bernstam L.I. Vaughn F.L. Bernstein I.A. Keratinocytes grown at the air-liquid interface In Vitro Cell Dev Biol 22 1986 695 705
38. William ML. Brown BE. Monger DJ. Grayson S. Elias PM: Lipid content and metabolism of human keratinocyte cultures grown at the air-medium interface. J Cell Physiol (in press)
39. Elsbach P. Farrow S. Cellular triglyceride as a source of fatty acid for lecithin synthesis during phagocytosis Biochim Biophys Acta 176 1969 438 441
40. Cook H.W. Clarke J.T.R. Spence M.W. Involvement of triacylglycerol in the metabolism of fatty acids by cultured neuroblastoma and glioma cells J Lipid Res 23 1982 1292 1300
41. Cook H.W. Spence M.W. Triacylglycerol as a precursor in phospholipid biosynthesis in cultured neuroblastoma cells: Studies with labeled glucose, fatty acid, and triacylglycerol Can J Biochem Cell Biol 63 1985 919 926
42. Pelech S.L. Vance D.E. Regulation of phosphatidylcholine biosynthesis Biochim Biophys Acta 779 1984 217 251
43. Williams M.L. Elias P.M. Elevated n-alkanes in congenital ichthyosiform erythroderma: Phenotypic differentiation of two types of autosomal recessive ichthyosis J Clin Invest 74 1984 296 300
44. Mangold H.K. Paltauf F. Ether Lipids Biochemical and Biomedical Aspects 1983 Academic Press New York
45. Rizzo W.B. Dammann A.L. Craft D. Sjogren-Larsson syndrome: Impaired fatty alcohol oxidation in cultured fibroblasts due to deficient fatty alcohol: NAD+oxidoreductase activity J Clin Invest 81 1988 738 744
46. Wakil S.J. Stoops J.K. Joshi V.C. Fatty acid synthesis and its regulation Ann Rev Biochem 52 1983 537 579
47. Borowitz M.J. Blum J.J. Triacylglycerol turnover in Tetrahymena pyriformis . Relation to phospholipid biosynthesis Biochim Biophys Acta 424 1976 114 124