Modification of Macrolide Antibiotics. Synthesis of 11-Deoxy-11-(carboxyamino)-6-o-methylerythromycin A 11,12-(Cyclic esters) via an Intramolecular Michael Reaction of o-Carbamates with an α,β-Unsaturated Ketone

Journal of Organic Chemistry

Volumn 53, Issue 10, 1988, Pages 2340-2345

  Baker, William R ^a   Clark, Jerry D ^a   Stephens, Richard L ^a   Kim, Ki H ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ERYTHROMYCIN DERIVATIVE;

DRUG SYNTHESIS; METHODOLOGY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE;

EID: 0023901653     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo00245a038     Document Type: Article

References (15)

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11. Kingsley, E.; Gray, P.; Tolman, K. G.; Tweedale, R. J. Clin. Pharmacol. 1983, 23, 178.
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