A human inhibitor of tumor necrosis factor α

Journal of Experimental Medicine

Volumn 167, Issue 4, 1988, Pages 1511-1516

  Seckinger, Philippe ^a   Isaaz, Sylvia ^a   Dayer, Jean Michel ^a  

^a University Hospital ^*  (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 1; TUMOR NECROSIS FACTOR;

FEVER; HUMAN; URINE;

CARCINOMA, SMALL CELL; CHROMATOGRAPHY, GEL; FEVER; HISTIOCYTOSIS, MALIGNANT; HUMAN; L CELLS (CELL LINE); MOLECULAR WEIGHT; MYOSITIS; SEPTICEMIA; SUPPORT, NON-U.S. GOV'T; TUMOR NECROSIS FACTOR; URINE;

EID: 0023899562     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.167.4.1511     Document Type: Article

References (10)

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2. Beuder, B., D. Greenwald, J. D. Hulmes, M. Chang, Y.-C. E. Pan, J. Mathison, R. Ulevitch, and A. Cerami. 1985. Identity of tumor necrosis factor and the macro-phage-secreted factor cachectin. Nature (Lond.). 316: 552.
3. Le, J., and J. Vilcek. 1987. Tumor necrosis factor and interleukin 1: cytokines with multiple overlapping biological activities. Lab. Invest. 56: 234.
4. 2 production by human synovial cells and dermal fibroblasts. J. Exp. Med, 162: 2163.
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6. Seckinger, P., and J.-M. Dayer. 1987. Interleukin-1 inhibitors. Ann. Inst. Pasteur Immunol. 138: 486.
7. Seckinger, P., K. Williamson, J.-F. Balavoine, B. Mach, G. Mazzei, A. Shaw, and J.-M. Dayer. 1987. A urine inhibitor of interleukin 1 activity affects both interleukin 1α and 1β but not tumor necrosis factor α. J. Immunol. 139: 1541.
8. Seckinger, P., J. W. Lowenthal, K. Williamson, J.-M. Dayer, and H. R. MacDonald. 1987. A urine inhibitor of interleukin 1 activity that blocks ligand binding. J. Immunol. 139: 1546.
9. Nedwin, G. E., L. P. Svedersky, T. S. Bringman, M. A. Palladino, Jr., and D. V. Goeddel. 1985. Effect of interleukin 2, interferon-γ, and mitogens on the production of tumor necrosis factors α and β. J. Immunol. 135: 2492.
10. 2 and collagenase production by fibroblasts and synovial cells is regulated by urine-derived human interleukin 1 and inhibitor(s). J. Clin. Invest. 78: 1120.