In vivo studies on the relationship between intestinal iron (Fe3+) absorption, hypoxia and erythropoiesis in the mouse

British Journal of Haematology

Volumn 68, Issue 3, 1988, Pages 373-378

  Raja, K B ^a   Simpson, R J ^a   Pippard, M J ^a   Peters, T J ^a  

^a MRC Clinical Research Centre   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

IRON; IRON 59;

ANIMAL EXPERIMENT; ERYTHROPOIESIS; HYPOXIA; INTESTINE; IRON ABSORPTION; MOUSE; NONHUMAN;

EID: 0023897841     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2141.1988.tb04217.x     Document Type: Article

References (23)

1. Anagnostou, A., Vercellotti, G., Barone, J. & Fried, W. (1976) Factors which affect erythropoiesis in partially nephrectomized and sham operated rats. Blood, 48, 425–433.
2. Beutler, E. & Buttenweiser, E. (1960) The regulation of iron absorption, I. A search for humoral factors. Journal of Laboratory and Clinical Medicine, 55, 274–280.
3. Bjarnason, I., Smethurst, P., Levi, A. J. & Peters, T. J. (1985) Intestinal permeability to 51 Cr‐EDTA in rats with experimentally induced enteropathy. Gut, 26, 579–586.
4. Bothwell, T. H., Pirzio‐Biroli, G. & Finch, C. A. (1958) Iron absorption. I. Factors influencing absorption. Journal of Laboratory and Clinical Medicine, 51, 24–36.
5. Brittin, G. M., Haley, J. & Brecher, G. (1968) Enhancement of intestinal iron absorption by a humoral effect of hypoxia in parabiotic rats. Proceedings of the Society for Experimental Biology and Medicine, 128, 178–184.
6. Cavill, I., Worwood, M. & Jacobs, A. (1975) Internal regulation of iron absorption. Nature, 256, 328–329.
7. Conrad, M. E., Foy, A. L., Williams, W. L. & Knospe, W. H. (1967) The effect of starvation and protein depletion upon ferrokinetics and iron absorption. American Journal of Physiology, 213, 557–565.
8. Conrad, M. E. & Barton, J. C. (1981) Factors affecting iron balance, American Journal of Hematology, 10, 199–215.
9. Cronquist, A. G., Mackenzie, J. & Smith, T. (1975) A high resolution bulk sample counter with variable geometry. International Journal of Applied Radiation and Isotopes, 26, 89–91.
10. Finch, C. A., Huebers, H., Eng, M. & Miller, L. (1982) Effect of transfused reticulocytes on iron exchange. Blood, 59, 364–369.
11. Forth, W. & Rummel, W. (1973) Iron absorption. Physiological Reviews, 53, 724–792.
12. Hathorn, M. K. S. (1971) The influence of hypoxia on iron absorption in the rat. Gastroenterology, 60, 76–81.
13. Jacobs, A. & Worwood, M. (1975) Iron absorption: present state of the art. British Journal of Haematology. 39 (Suppl.), 89–101.
14. Mason, C. & Thomas, T. H. (1984) A model for erythropoiesis in experimental chronic renal failure. British Journal of Haematology, 58, 729–740.
15. Mendel, G. A. (1961) Studies on iron absorption, I. The relationships between the rate of erythropoiesis, hypoxia and iron absorption. Blood, 18, 727–736.
16. Peschle, C., Jori, G. P., Marone, G. & Condorelli, M. (1974) Independence of iron absorption from the rate of erythropoiesis. Blood, 44, 353–358.
17. Pirzio‐Biroli, G. & Finch, C. A. (1960) Iron absorption. III. The influence of the iron stores on iron absorption in the normal subject. Journal of Laboratory and Clinical Medicine, 55, 216–220.
18. Raja, K. B., Pippard, M. J., Simpson, R. J. & Peters, T. J. (1986) Relationship between erythropoiesis and the enhanced intestinal uptake of ferric iron in hypoxia in the mouse. British Journal of Haematology, 64, 587–593.
19. Raja, K. B., Simpson, R. J. & Peters, T. J. (1987a) Comparison of 59 Fe 3+ uptake in vitro and in vivo by mouse duodenum. Biochimica et Biophysica Acta, 901, 52–60.
20. Raja, K. B., Bjarnason, I., Simpson, R. J. & Peters, T. J. (1987b) In vitro measurement and adaptive response of Fe 3+ uptake by mouse intestine. Cell Biochemistry and Function, 5, 69–76.
21. Reynafarje, C. & Ramos, J. (1961) Influence of altitude changes on intestinal iron absorption. Journal of Laboratory and Clinical Medicine, 57, 848–855.
22. Rosenmund, A., Gerber, S., Huebers, H. & Finch, C. (1980) Regulation of iron absorption and storage iron turnover. Blood, 56, 30–37.
23. Weintraub, L. R., Conrad, M. E. & Crosby, W. H. (1965) Regulation of the intestinal absorption of iron by the rate of erythropoiesis. British Journal of Haematology, 11, 432–438.