Kinetic mechanism and substrate specificity of glutathione peroxidase activity of ebselen (PZ51)

Biochemical Pharmacology

Volumn 37, Issue 11, 1988, Pages 2267-2271

  Maiorino, Matilde ^a   Roveri, Antonella ^a   Coassin, Mariagrazia ^a   Ursini, Fulvio ^a  

^a UNIVERSITY OF PADOVA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

EBSELEN; GLUTATHIONE PEROXIDASE; LIPID PEROXIDE; PHOSPHATIDYLCHOLINE;

ANIMAL CELL; LIVER; RAT;

ANTIOXIDANTS; AZOLES; GLUTATHIONE PEROXIDASE; HYDROGEN PEROXIDE; KINETICS; LIPID PEROXIDES; SELENIUM; SUBSTRATE SPECIFICITY;

EID: 0023891447     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(88)90591-6     Document Type: Article

References (21)

1. The Catalytic Decomposition of Hydrogen Peroxide by Iron Salts
2. A novel biologically active seleno-organic compound—1
3. A novel biologically active selenoorganic compound—IV
4. Purification and characterization of selenium-glutathione peroxidase from hamster liver
5. Evidence of peroxidase activity of the peroxidation inhibiting protein on dilinoleyl phosphatidylcholine hydroperoxide as obtained in direct electron impact conditions
6. Mechanism of the Catalytic Reduction of Hydroperoxides by Ebselen : A Selenium - 77 Nmr Study