Binaltorphimine-Related Bivalent Ligands and their κ Opioid Receptor Antagonist Selectivity

Journal of Medicinal Chemistry

Volumn 31, Issue 4, 1988, Pages 836-841

  Portoghese, P S ^a   Nagase, H ^a   Lipkowski, A W ^a   Larson, D L ^a   Takemori, A E ^b  

^a Division of Medicinal Chemistry and Pharmocognosy   (United States)

^b UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINALTORPHIMINE; KAPPA OPIATE RECEPTOR; MORPHINAN DERIVATIVE; NALTREXONE; NALTREXONE DERIVATIVE; NORBINALTORPHIMINE;

ANIMAL CELL; BIOLOGICAL MODEL; DRUG ANTAGONISM; DRUG RECEPTOR BINDING; GUINEA PIG; MOUSE; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ANIMAL; CHEMISTRY; CYCLAZOCINE; ENKEPHALIN, LEUCINE; ENKEPHALIN, LEUCINE-2-ALANINE; ETHYLKETOCYCLAZOCINE; GUINEA PIGS; MALE; MICE; MODELS, MOLECULAR; MORPHINE; MUSCLE, SMOOTH; NALTREXONE; RECEPTORS, OPIOID; RECEPTORS, OPIOID, KAPPA; STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0023889865     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00399a026     Document Type: Article

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