A new 5-lipoxygenase selective inhibitor derived from Artocarpus communis strongly inhibits arachidonic acid-induced ear edema

Biochemical Pharmacology

Volumn 37, Issue 11, 1988, Pages 2161-2165

  Koshihara, Yasuko ^a   Fujimoto, Yasuo ^b   Inoue, Hideo ^c  

^a TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

^b INST OF PHYS AND CHEMICAL RESEARCH   (Japan)

^c Minophagen Pharmaceutical Co   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONATE 5 LIPOXYGENASE; ARACHIDONIC ACID; LEUKOTRIENE; RADIOISOTOPE;

ANIMAL CELL; EAR EDEMA; HIGHER PLANT; INFLAMMATION; MASTOCYTOMA; MOUSE; PERITONEUM;

ANIMAL; ARACHIDONATE 5-LIPOXYGENASE; ARACHIDONATE LIPOXYGENASES; ARACHIDONIC ACID; ARACHIDONIC ACIDS; CHALCONE; DOSE-RESPONSE RELATIONSHIP, DRUG; EDEMA; MALE; MICE; MICE, INBRED ICR; PLANT EXTRACTS; PROPIOPHENONES; SRS-A; TERPENES;

EID: 0023889059     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(88)90576-X     Document Type: Article

References (13)

1. Abstract in Kyoto Conference on Prostaglandins
2. Leukotrienes promote plasma leakage and leukocyte adhesion in postcapillary venules: in vivo effects with relevance to the acute inflammatory response.