Establishing Airborne Exposure Control Limits in the Pharmaceutical Industry

American Industrial Hygiene Association Journal

Volumn 49, Issue 6, 1988, Pages 309-313

  Sargent, Edward V ^a   Kirk, G David ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG;

AIR POLLUTION CONTROL; DRUG INDUSTRY; INDUSTRIAL WORKER; MAXIMUM ALLOWABLE CONCENTRATION; SHORT SURVEY; WORKROOM AIR;

DRUG INDUSTRY; DRUG TOXICITY; ENVIRONMENTAL EXPOSURE; HUMAN; OCCUPATIONAL DISEASES;

EID: 0023888130     PISSN: 00028894     EISSN: None     Source Type: Journal    
DOI: 10.1080/15298668891379792     Document Type: Article

References (16)

1. The Association of the British Pharmaceutical Industry: Draft Guidelines for the Control of Exposure in the Manufacture of Pharmaceuticals. London: Association of the British Pharmaceutical Industry, 1984.
2. Shmunes, E., J.S. Taylor, L.D. Petz, G. Garatty and H.H. Fudenberg: Immunologic Reactions in Penicillin Factory Workers. Ann. Allergy. 36:313–323 (1976).
3. Vil’Sanskaja, F.L. and G.B. Steinberg: Modification of the Bacteria of the Intestine and Other Organs Following Occupational Exposure to Antibiotics (Streptomycin, Tetracycline, Penicillin). Gig. Tr. Prof. Zabol. 14:25–31 (1970).
4. Stejskal, V.D.M., R. Olin and M. Forsbeck: Diagnosis of Drug-Induced Occupational Allergy by Lymphocyte Transformation Test. In Developments in the Science and Practice of Toxicology, edited by A.W. Hayes, R.C. Schnell and T.S. Miya. New York: Elsevier Science Publishers, 1983. pp. 559–562.
5. Ekenvall, L.and M. Forsbeck: Contact Eczema Produced by a B-Adrenergic Blocking Agent (Alprenolol). Contact Dermatitis. 4:190–194 (1978).
6. Hardie, R.A., J.A. Savin, D.A. White and S. Pumford: Quinine Dermatitis: Investigation of a Factory Outbreak. Contact Dermatitis. 4:121–124 (1978).
7. Newton, R.W., M.C.K. Browning, J. Iqbal, N. Piercy and D.G. Adamson: Adrenocortical Suppression in Workers Manufacturing Synthetic Glucocorticoids. Br. Med. J. 1:73–74, (1978).
8. American Conference of Governmental Industrial Hygienists: Threshold Limit Values for Chemical Substances in the Work Environment Adopted by ACGIH with Intended Changes for 1985–1986. Cincinnati, Ohio: American Conference of Governmental Industrial Hygienists, 1985. p. 6.
9. National Research Council, Commission on Life Sciences, Committee on the Institutional Means for Assessment of Risks to Public Health: Risk Assessment in the Federal Government: Managing the Process. Washington, D.C.: National Academy Press, 1983.
10. Calabrese, E.J.: Principles of Animal Extrapolation. New York: John Wiley and Sons, 1983. pp. 537–555.
11. Bigwood, E.J.: The Acceptable Daily Intake of Food Addi-tives. CRC Crit. Rev. Toxicol. June:41–93 (1973).
12. Dourson, M.L. and J.F. Stara: Regulatory History and Experimental Support of Uncertainty (Safety) Factors. Reg. Toxicol. Pharmacol. 3:224–238 (1983).
13. James, R.C.: Risk Assessment. In Industrial Toxicology, edited by P.L. Williams and J.L. Burson. New York: Van Nostrand Reinhold Company, 1985. pp. 369–398.
14. Bondi, J.V., H.B. Hacker, K.C. Yeh and K.C. Kwan: Bioavailability Assessment under Quasi and Nonsteady State Conditions III: Application. J. Pharm. Sci. 65:1657–1665 (1976).
15. Woolrich, P.F.: Antibiotics, Steroids, and Potent Drugs in Industrial Hygiene Aspects of Plant Operations, Volume 1, Process Flows, edited by L.V. Cralley and L.J. Cralley. New York: MacMillan Publishing Co., Inc., 1982. pp. 67–81.
16. Paustenbach, D. and R. Langner: Corporate Occupational Exposure Limits: The Current State of Affairs. Am. Ind. Hyg. Assoc. J. 47:809–818 (1986).