Quinolinic acid lesions of rat striatum abolish D1- and D2-dopamine receptor-mediated catalepsy

Brain Research

Volumn 450, Issue 1-2, 1988, Pages 403-407

  Calderon, Stephen F ^a   Sanberg, Paul R ^a   Norman, Andrew B ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

Catalepsy; Haloperidol; Kainic acid; Neuroleptic; Quinolic acid; SCH23390; Striatum

Indexed keywords

8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; HALOPERIDOL; KAINIC ACID; NEUROTOXIN; QUINOLINIC ACID;

ANIMAL EXPERIMENT; CATALEPSY; CORPUS STRIATUM; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMAL; BENZAZEPINES; CATALEPSY; CORPUS STRIATUM; HALOPERIDOL; MALE; PYRIDINES; QUINOLINIC ACID; QUINOLINIC ACIDS; RATS; RATS, INBRED STRAINS; RECEPTORS, DOPAMINE; RECEPTORS, DOPAMINE D1; RECEPTORS, DOPAMINE D2; SCH-23390; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0023882827     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-8993(88)91584-3     Document Type: Article

References (20)

1. ‘Selective’ D-1 and D-2 receptor antagonists fail to differentially alter supersensitive locomotor behavior in the rat
2. Replication of the neurochemical charateristics of Huntingon's disease by quinolinic acid
3. Quinolinic acid does not spare striatal neuropeptide Y-immunoreactive neurons
4. Tissue levels of haloperidol by radioreceptor assay and behavioral effects of haloperidol in the rat
5. Cholinergic and neuroleptic-induced catalepsy: modification by lesions in the caudate putamen
6. Dopamine receptor binding predicts clinical and pharmacological potencies of antischizophrenic drugs
7. No evidence for preservation of somatostatin-containing neurons after intrastriatal injections of quinolinic acid
8. The quinolinic acid model of Huntington's disease: dose dependent effects on behavior
9. No detectable remote lesions following massive intrastriatal injections of ibonetic acid
10. SCH23390, a potential benzazepine antipsychotic with unique interactions of dopaminergic systems
11. Multiple receptors for dopamine
12. 2 blockade phenomenon?
13. Evidence on the cellular localization of adenyl cyclase in the neostriatum
14. Haloperidol-induced catalepsy is mediated by post-synaptic dopamine receptors
15. Body weight, feeding, and drinking behaviors in rats with kainic acid-induced lesions of striatal neurons. With a note on body weight symptomatology in Huntington's disease
16. Kainic acid injections in the striatum alter the cataleptic and locomotor effects of drugs influencing dopaminergic and cholinergic systems
17. Excitotoxic models for neurodegenerative disorders
18. Antipsychotic drug doses and neuroleptic/dopamine receptors