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Volumn 48, Issue 1, 1986, Pages 1-8

Protein Kinase C as the Receptor for the Phorbol Ester Tumor Promoters: Sixth Rhoads Memorial Award Lecture

Author keywords

[No Author keywords available]

Indexed keywords

PHORBOL ESTER; PROTEIN KINASE C; TUMOR PROMOTER;

EID: 0023880172     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (427)

References (67)
  • 1
    • 0014353314 scopus 로고
    • Cocarcinogenic principles from the seed oil of Croton tiglium and from other Euphorbiaceae
    • Heckcer, E. Cocarcinogenic principles from the seed oil of Croton tiglium and from other Euphorbiaceae. Cancer Res., 28:2338-2349,1968.
    • (1968) Cancer Res. , vol.28 , pp. 2338-2349
    • Heckcer, E.1
  • 2
    • 77954577665 scopus 로고
    • The function and mechanism of promoters of carcinogenesis
    • Boutwell, R. K. The function and mechanism of promoters of carcinogenesis. Crit. Rev. Toxicol., 2:419-443,1974.
    • (1974) Crit. Rev. Toxicol. , vol.2 , pp. 419-443
    • Boutwell, R.K.1
  • 3
    • 0019264172 scopus 로고
    • In vitro studies on the mode of action of the phorbol esters, potent tumor promoters
    • Blumberg, P. M. In vitro studies on the mode of action of the phorbol esters, potent tumor promoters. Crit. Rev. Toxicol., 8:153-234, 1981.
    • (1981) Crit. Rev. Toxicol. , vol.8 , pp. 153-234
    • Blumberg, P.M.1
  • 5
    • 0021741812 scopus 로고
    • Tumor promoters and cell transformation
    • Diamond, L. Tumor promoters and cell transformation. Pharmacol. Ther., 26:89-145, 1984.
    • (1984) Pharmacol. Ther. , vol.26 , pp. 89-145
    • Diamond, L.1
  • 6
    • 0010708038 scopus 로고
    • Specific binding of phorbol ester tumor promoters
    • Driedger, P. E., and Blumberg, P. M. Specific binding of phorbol ester tumor promoters. Proc. Natl. Acad. Sci. USA, 77:567-571,1980.
    • (1980) Proc. Natl. Acad. Sci. USA , vol.77 , pp. 567-571
    • Driedger, P.E.1    Blumberg, P.M.2
  • 7
    • 0038226991 scopus 로고
    • Specific receptors for phorbol ester tumor promoters and their involvement in biological responses
    • T. J. Slaga (ed.) Boca Raton, FL: CRC Press
    • Blumberg, P. M., Dunn, J. A., Jaken, S., Jeng, A. Y., Leach, K. L., Sharkey, N. A., and Yeh, E. Specific receptors for phorbol ester tumor promoters and their involvement in biological responses. In: T. J. Slaga (ed.), Mechanisms of Tumor Promotion, Vol. 3, pp. 143–184. Boca Raton, FL: CRC Press, 1984.
    • (1984) Mechanisms of Tumor Promotion , vol.3 , pp. 143-184
    • Blumberg, P.M.1    Dunn, J.A.2    Jaken, S.3    Jeng, A.Y.4    Leach, K.L.5    Sharkey, N.A.6    Yeh, E.7
  • 8
    • 0019844170 scopus 로고
    • Direct measurement of specific binding of highly lipophilic phorbol diester to mouse epidermal membranes using cold acetone
    • Ashendel, C. L., and Boutwell, R. K. Direct measurement of specific binding of highly lipophilic phorbol diester to mouse epidermal membranes using cold acetone. Biochem. Biophys. Res. Commun., 99: 543-549,1981.
    • (1981) Biochem. Biophys. Res. Commun. , vol.99 , pp. 543-549
    • Ashendel, C.L.1    Boutwell, R.K.2
  • 9
    • 0021227676 scopus 로고
    • The role of protein kinase C in cell surface signal transduction and tumor promotion
    • Nishizuka, Y. The role of protein kinase C in cell surface signal transduction and tumor promotion. Nature (Lond.) 308:693-698,1984.
    • (1984) Nature (Lond.) , vol.308 , pp. 693-698
    • Nishizuka, Y.1
  • 10
    • 0023052241 scopus 로고
    • Studies and perspectives of protein kinase C
    • Nishizuka, Y. Studies and perspectives of protein kinase C. Science (Wash. DC), 233:305-312,1986.
    • (1986) Science (Wash. DC) , vol.233 , pp. 305-312
    • Nishizuka, Y.1
  • 11
    • 0020326790 scopus 로고
    • Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters
    • Castagna, M., Takai, Y., Kaibuchi, K., Sano, K., Kikkawa, U., and Nishizuka, Y. Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters. J. Biol. Chem., 257:7847-7851, 1982.
    • (1982) J. Biol. Chem. , vol.257 , pp. 7847-7851
    • Castagna, M.1    Takai, Y.2    Kaibuchi, K.3    Sano, K.4    Kikkawa, U.5    Nishizuka, Y.6
  • 13
    • 0020540144 scopus 로고
    • Identification of high-affinity phorbol ester receptor in cytosol of EL4 thymoma cells: requirement for calcium, magnesium, and phospholipids
    • Sando, J. J., and Young, M. C. Identification of high-affinity phorbol ester receptor in cytosol of EL4 thymoma cells: requirement for calcium, magnesium, and phospholipids. Proc. Natl. Acad. Sci. USA, 80:2642-2646,1983.
    • (1983) Proc. Natl. Acad. Sci. USA , vol.80 , pp. 2642-2646
    • Sando, J.J.1    Young, M.C.2
  • 14
    • 0020603023 scopus 로고
    • Protein kinase activity associated with a phorbol ester receptor purified from mouse brain
    • Ashendel, C. L., Staller, J. M., and Boutwell, R. K. Protein kinase activity associated with a phorbol ester receptor purified from mouse brain. Cancer Res., 43:4333-4337, 1983.
    • (1983) Cancer Res. , vol.43 , pp. 4333-4337
    • Ashendel, C.L.1    Staller, J.M.2    Boutwell, R.K.3
  • 15
    • 0003053406 scopus 로고
    • Characterization of a specific phorbol ester aporeceptor in mouse brain cytosol
    • Leach, K. L., James, M. L., and Blumberg, P. M. Characterization of a specific phorbol ester aporeceptor in mouse brain cytosol. Proc. Natl. Acad. Sci. USA, 80:4208-4212, 1983.
    • (1983) Proc. Natl. Acad. Sci. USA , vol.80 , pp. 4208-4212
    • Leach, K.L.1    James, M.L.2    Blumberg, P.M.3
  • 16
    • 0021443856 scopus 로고
    • Inositol trisphosphate and diacylglycerol as second messengers
    • Berridge, M. J. Inositol trisphosphate and diacylglycerol as second messengers. Biochem. J., 220: 345–360, 1984.
    • (1984) Biochem. J. , vol.220 , pp. 345-360
    • Berridge, M.J.1
  • 18
    • 0022970190 scopus 로고
    • Quantitative measurement of sn-1,2-diacylglycerols present in platelets, hepatocytes, and ras- and sis-transformed normal rat kidney cells
    • Preiss, J., Loomis, C. R., Bishop, W. R., Stein, R., Niedel, J. E., and Bell, R. M. Quantitative measurement of sn-1,2-diacylglycerols present in platelets, hepatocytes, and ras- and sis-transformed normal rat kidney cells. J. Biol. Chem., 261:8597-8600,1986.
    • (1986) J. Biol. Chem. , vol.261 , pp. 8597-8600
    • Preiss, J.1    Loomis, C.R.2    Bishop, W.R.3    Stein, R.4    Niedel, J.E.5    Bell, R.M.6
  • 19
    • 0021221071 scopus 로고
    • Transforming protein of avian sarcoma virus UR2 is associated with phosphatidylinositol kinase activity: possible role in tumorigenesis
    • Macara, I. G., Marinetti, G. V., and Balduzzi, P. C. Transforming protein of avian sarcoma virus UR2 is associated with phosphatidylinositol kinase activity: possible role in tumorigenesis. Proc. Natl. Acad. Sci. USA, 81: 2728–2732, 1984.
    • (1984) Proc. Natl. Acad. Sci. USA , vol.81 , pp. 2728-2732
    • Macara, I.G.1    Marinetti, G.V.2    Balduzzi, P.C.3
  • 21
    • 0021220257 scopus 로고
    • Protein kinase C phosphorylation of the EGF receptor at a threonine residue close to the cytoplasmic face of the plasma membrane
    • Hunter, T., Ling, N., and Cooper, J. A. Protein kinase C phosphorylation of the EGF receptor at a threonine residue close to the cytoplasmic face of the plasma membrane. Nature (Lond.), 311:480-483,1984.
    • (1984) Nature (Lond.) , vol.311 , pp. 480-483
    • Hunter, T.1    Ling, N.2    Cooper, J.A.3
  • 22
    • 0016287690 scopus 로고
    • Effect of tumor-promoting phorbol esters on the normal and the isoproterenol-elevated level of adenosine 3‘,5'-cyclic monophosphate in mouse epidermis in vivo
    • Grimm, W., and Marks, F. Effect of tumor-promoting phorbol esters on the normal and the isoproterenol-elevated level of adenosine 3‘,5'-cyclic monophosphate in mouse epidermis in vivo. Cancer Res., 34:3128-3134,1974.
    • (1974) Cancer Res. , vol.34 , pp. 3128-3134
    • Grimm, W.1    Marks, F.2
  • 23
    • 0017360627 scopus 로고
    • The effect of the phorbol ester tumor promoters on their basal and catecholamine-stimulated levels of cyclic adenosine 3‘:5'-monophosphate in mouse skin and epidermis in vivo
    • Mufson, R. A., Simsiman, R. C., and Boutwell, R. K. The effect of the phorbol ester tumor promoters on their basal and catecholamine-stimulated levels of cyclic adenosine 3‘:5'-monophosphate in mouse skin and epidermis in vivo. Cancer Res., 37: 665–669, 1977.
    • (1977) Cancer Res. , vol.37 , pp. 665-669
    • Mufson, R.A.1    Simsiman, R.C.2    Boutwell, R.K.3
  • 24
    • 0022549501 scopus 로고
    • Protein kinase C phosphorylates human platelet inositol trisphosphate 5‘-phosphomonoester-ase, increasing the phosphatase activity
    • Connolly, T. M., Lawing, W. J., and Majerus, P. W. Protein kinase C phosphorylates human platelet inositol trisphosphate 5‘-phosphomonoester-ase, increasing the phosphatase activity. Cell, 46:951-958,1986.
    • (1986) Cell , vol.46 , pp. 951-958
    • Connolly, T.M.1    Lawing, W.J.2    Majerus, P.W.3
  • 26
    • 0022969855 scopus 로고
    • Induction of c-fos and c-myc mRNA by epidermal growth factor or calcium ionophore is cAMP dependent
    • Ran, W., Dean, M., Levine, R. A., Henkle, C., and Campisi, J. Induction of c-fos and c-myc mRNA by epidermal growth factor or calcium ionophore is cAMP dependent. Proc. Natl. Acad. Sci. USA, 83:8216-8220,1986.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 8216-8220
    • Ran, W.1    Dean, M.2    Levine, R.A.3    Henkle, C.4    Campisi, J.5
  • 27
    • 0023023281 scopus 로고
    • Modulation of c-fos and c-myc mRNA levels in normal human lymphocytes by calcium ionophore A23187 and phorbol ester
    • Grausz, J. D., Fradelizi, D., Dautry, F., Monier, R., and Lehn, P. Modulation of c-fos and c-myc mRNA levels in normal human lymphocytes by calcium ionophore A23187 and phorbol ester. Eur. J. Immunol., 16: 1217–1221, 1986.
    • (1986) Eur. J. Immunol. , vol.16 , pp. 1217-1221
    • Grausz, J.D.1    Fradelizi, D.2    Dautry, F.3    Monier, R.4    Lehn, P.5
  • 28
    • 0020033880 scopus 로고
    • 3H]phorbol 12,13-dibutyrate in the nematode Caenorhabditis elegans, a manipulable genetic system
    • 3H]phorbol 12,13-dibutyrate in the nematode Caenorhabditis elegans, a manipulable genetic system. Teratogen. Carcinogen. Mutagen. 2:19-30,1982.
    • (1982) Teratogen. Carcinogen. Mutagen. , vol.2 , pp. 19-30
    • Lew, K.K.1    Chritton, S.2    Blumberg, P.M.3
  • 29
    • 1842394775 scopus 로고
    • Competitive inhibition by diacylglycerol of specific phorbol ester binding
    • Sharkey, N. A., Leach, K. L., and Blumberg, P. M. Competitive inhibition by diacylglycerol of specific phorbol ester binding. Proc. Natl. Acad. Sci. USA, 81:607-610, 1984.
    • (1984) Proc. Natl. Acad. Sci. USA , vol.81 , pp. 607-610
    • Sharkey, N.A.1    Leach, K.L.2    Blumberg, P.M.3
  • 30
    • 0022332395 scopus 로고
    • Kinetic evidence that 1,2-diolein inhibits phorbol ester binding to protein kinase C via a competitive mechanism
    • Sharkey, N. A., and Blumberg, P. M. Kinetic evidence that 1,2-diolein inhibits phorbol ester binding to protein kinase C via a competitive mechanism. Biochem. Biophys. Res. Commun., 133:1051-1056,1985.
    • (1985) Biochem. Biophys. Res. Commun. , vol.133 , pp. 1051-1056
    • Sharkey, N.A.1    Blumberg, P.M.2
  • 31
    • 0021971695 scopus 로고
    • Stoichiometric binding of diacylglycerol to the phorbol ester receptor
    • Konig, B., DiNitto, P. A., and Blumberg, P. Stoichiometric binding of diacylglycerol to the phorbol ester receptor. J. Cell. Biochem., 29: 37–44, 1985.
    • (1985) J. Cell. Biochem. , vol.29 , pp. 37-44
    • Konig, B.1    DiNitto, P.A.2    Blumberg, P.3
  • 32
    • 0022341259 scopus 로고
    • Activation of protein kinase-C by Triton X-100 mixed micelles containing diacylglycerol and phosphati-dylserine
    • Hannun, J. A., Loomis, C. R., and Bell, R. M. Activation of protein kinase-C by Triton X-100 mixed micelles containing diacylglycerol and phosphati-dylserine. J. Biol. Chem., 260:39-43,1985.
    • (1985) J. Biol. Chem. , vol.260 , pp. 39-43
    • Hannun, J.A.1    Loomis, C.R.2    Bell, R.M.3
  • 33
    • 0022991272 scopus 로고
    • Comparison of the activity of phorbol 12-myristate 13-acetate and the diglyceride glycerol 1-myristate 2-acetate
    • Sharkey, N. A., and Blumberg, P. M. Comparison of the activity of phorbol 12-myristate 13-acetate and the diglyceride glycerol 1-myristate 2-acetate. Carcinogenesis (Lond.), 7; 677-679,1986.
    • (1986) Carcinogenesis (Lond.) , vol.7 , pp. 677-679
    • Sharkey, N.A.1    Blumberg, P.M.2
  • 35
    • 0020962197 scopus 로고
    • Synergistic functions of protein phosphorylation and calcium mobilization in platelet activation
    • Kaibuchi, K., Takai, Y., Sawamura, M., Hoshijima, M., Fujikura, T., and Nishizuka, Y. Synergistic functions of protein phosphorylation and calcium mobilization in platelet activation. J. Biol. Chem., 258:6701-6704,1983.
    • (1983) J. Biol. Chem. , vol.258 , pp. 6701-6704
    • Kaibuchi, K.1    Takai, Y.2    Sawamura, M.3    Hoshijima, M.4    Fujikura, T.5    Nishizuka, Y.6
  • 37
    • 0022372865 scopus 로고
    • Similar effects of phospholipase C and phorbol ester tumor promoters on primary mouse epidermal cells
    • Jeng, A. Y., Lichti, U., Strickland, J. E., and Blumberg, P. M. Similar effects of phospholipase C and phorbol ester tumor promoters on primary mouse epidermal cells. Cancer Res., 45:5714-5721, 1985.
    • (1985) Cancer Res. , vol.45 , pp. 5714-5721
    • Jeng, A.Y.1    Lichti, U.2    Strickland, J.E.3    Blumberg, P.M.4
  • 38
    • 0343465635 scopus 로고
    • Role of protein kinase C in diacylglycerol-mediated induction of ornithine decarboxylase and reduction of epidermal growth factor binding
    • Jetten, A. M., Ganong, B. R., Vandenbark, G. R., Shirley, J. E., and Bell, R. M. Role of protein kinase C in diacylglycerol-mediated induction of ornithine decarboxylase and reduction of epidermal growth factor binding. Proc. Natl. Acad. Sci. USA, 82:1941-1945,1985.
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 1941-1945
    • Jetten, A.M.1    Ganong, B.R.2    Vandenbark, G.R.3    Shirley, J.E.4    Bell, R.M.5
  • 39
    • 0022343275 scopus 로고
    • R 59 022, a diacylglycerol kinase inhibitor. Its effect on diacylglycerol and thrombin-induced C kinase activation in the intact platelet
    • de Chaffoy de Courcelles, D., Roevens, P., and Van Belle, H. R 59 022, a diacylglycerol kinase inhibitor. Its effect on diacylglycerol and thrombin-induced C kinase activation in the intact platelet. J. Biol. Chem., 260:15762-15770, 1985.
    • (1985) J. Biol. Chem. , vol.260 , pp. 15762-15770
    • de Chaffoy de Courcelles, D.1    Roevens, P.2    Van Belle, H.3
  • 40
    • 0021853150 scopus 로고
    • Inhibition of diacylglycerol acyltransferase by 2-bromooctanoate in cultured rate hepatocytes
    • Mayorek, N., and Bar-Tana, J. Inhibition of diacylglycerol acyltransferase by 2-bromooctanoate in cultured rate hepatocytes. J. Biol. Chem., 260:6528-6532, 1985.
    • (1985) J. Biol. Chem. , vol.260 , pp. 6528-6532
    • Mayorek, N.1    Bar-Tana, J.2
  • 41
    • 0021824442 scopus 로고
    • Dissociation of protein kinase C activation from phorbol ester-induced maturation of HL-60 leukemia cells
    • Kreutter, D., Caldwell, A. B., and Morin, M. J. Dissociation of protein kinase C activation from phorbol ester-induced maturation of HL-60 leukemia cells. J. Biol. Chem., 260:5979-5984,1985.
    • (1985) J. Biol. Chem. , vol.260 , pp. 5979-5984
    • Kreutter, D.1    Caldwell, A.B.2    Morin, M.J.3
  • 42
    • 0021247065 scopus 로고
    • Mechanism of action of the phorbol ester tumor promoters: specific receptors for lipophilic ligands
    • Blumberg, P. M., Jaken, S., Konig, B., Sharkey, N. A., Leach, K. L., Jeng, A. Y., and Yeh, E. Mechanism of action of the phorbol ester tumor promoters: specific receptors for lipophilic ligands. Biochem. Pharmacol., 33: 933-940,1984.
    • (1984) Biochem. Pharmacol. , vol.33 , pp. 933-940
    • Blumberg, P.M.1    Jaken, S.2    Konig, B.3    Sharkey, N.A.4    Leach, K.L.5    Jeng, A.Y.6    Yeh, E.7
  • 43
    • 0020638353 scopus 로고
    • 3H)-12-deoxyphor-bol 13-isobutyrate to phorbol ester receptor subclasses in mouse skin particulate preparations
    • 3H)-12-deoxyphor-bol 13-isobutyrate to phorbol ester receptor subclasses in mouse skin particulate preparations. Cancer Res., 43:4632-4637, 1983.
    • (1983) Cancer Res. , vol.43 , pp. 4632-4637
    • Dunn, J.A.1    Blumberg, P.M.2
  • 44
    • 84965820523 scopus 로고
    • 2+-sensitive, phospholipid-dependent protein kinase
    • D. Evered, J. Nugent, and J. Whelan (eds.) London: Pitman Publishing, Ltd
    • 2+-sensitive, phospholipid-dependent protein kinase. In: D. Evered, J. Nugent, and J. Whelan (eds.), Growth Factors in Biology and Medicine, pp. 205–233. London: Pitman Publishing, Ltd., 1985.
    • (1985) Growth Factors in Biology and Medicine , pp. 205-233
    • Rozengurt, E.1    Rodriguez-Pena, A.2    Sinnett-Smith, J.3
  • 45
    • 0022355371 scopus 로고
    • Activation of the human neutrophil nicotinamide adenine dinucleotide phosphate (NADPH)-oxidase by protein kinase C
    • Cox, J. A., Jeng, A. Y., Sharkey, N. A., Blumberg, P. M., and Tauber, A. I. Activation of the human neutrophil nicotinamide adenine dinucleotide phosphate (NADPH)-oxidase by protein kinase C. J. Clin. Invest., 76: 1932–1938, 1985.
    • (1985) J. Clin. Invest. , vol.76 , pp. 1932-1938
    • Cox, J.A.1    Jeng, A.Y.2    Sharkey, N.A.3    Blumberg, P.M.4    Tauber, A.I.5
  • 46
    • 0022996283 scopus 로고
    • Loss of Swiss 3T3 response to phorbol ester restored by microinjected protein kinase C
    • Pasti, G., Lacal, J.-C., Warren, B. S., Aaronson, S., and Blumberg, P. M. Loss of Swiss 3T3 response to phorbol ester restored by microinjected protein kinase C. Nature (Lond.), 324:375-377,1986.
    • (1986) Nature (Lond.) , vol.324 , pp. 375-377
    • Pasti, G.1    Lacal, J.-C.2    Warren, B.S.3    Aaronson, S.4    Blumberg, P.M.5
  • 47
    • 0023106936 scopus 로고
    • Isolation of cDNA clones encoding protein kinase C: evidence for a protein kinase C-related gene family
    • Housey, G. M., O'Brian, C. A., Johnson, M. D., Kirschmeier, P., and Weinstein, I. B. Isolation of cDNA clones encoding protein kinase C: evidence for a protein kinase C-related gene family. Proc. Natl. Acad. Sci. USA, 84:1065-1069,1987.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 1065-1069
    • Housey, G.M.1    O'Brian, C.A.2    Johnson, M.D.3    Kirschmeier, P.4    Weinstein, I.B.5
  • 51
    • 0023600266 scopus 로고
    • Modulation by palmitoylcarnitine of protein kinase C activation
    • Nakadate, T., and Blumberg, P. M. Modulation by palmitoylcarnitine of protein kinase C activation. Cancer Res., 47:6537-6542,1987.
    • (1987) Cancer Res. , vol.47 , pp. 6537-6542
    • Nakadate, T.1    Blumberg, P.M.2
  • 52
    • 0020698115 scopus 로고
    • 2+, phospholipid-dependent protein kinase associated with plasma membrane
    • 2+, phospholipid-dependent protein kinase associated with plasma membrane. Nature (Lond.) 301:621-623, 1983.
    • (1983) Nature (Lond.) , vol.301 , pp. 621-623
    • Kraft, A.S.1    Anderson, W.B.2
  • 53
    • 0020356002 scopus 로고
    • Decrease in cytosolic calcium/phospholipid-dependent protein kinase activity following phorbol ester treatment of EL4 thymoma cells
    • Kraft, A. S., Anderson, W. B., Cooper, H. L., and Sando, J. J. Decrease in cytosolic calcium/phospholipid-dependent protein kinase activity following phorbol ester treatment of EL4 thymoma cells. J. Biol. Chem., 257: 13193-13196,1982.
    • (1982) J. Biol. Chem. , vol.257 , pp. 13193-13196
    • Kraft, A.S.1    Anderson, W.B.2    Cooper, H.L.3    Sando, J.J.4
  • 54
    • 0023003536 scopus 로고
    • The involvement of calpain in the activation of protein kinase C in neutrophils stimulated by phorbol myristic acid
    • Melloni, E., Pontremoli, S., Michetti, M., Sacco, O., Sparatore, B., and Horecker, B. L. The involvement of calpain in the activation of protein kinase C in neutrophils stimulated by phorbol myristic acid. J. Biol. Chem., 261: 4101-4105,1986.
    • (1986) J. Biol. Chem. , vol.261 , pp. 4101-4105
    • Melloni, E.1    Pontremoli, S.2    Michetti, M.3    Sacco, O.4    Sparatore, B.5    Horecker, B.L.6
  • 55
    • 0018776318 scopus 로고
    • Binding of epidermal growth factor to primary and permanent cultures of mouse epidermal cells: inhibition by tumor-promoting phorbol esters
    • Murray, A. W., and Fusenig, N. E. Binding of epidermal growth factor to primary and permanent cultures of mouse epidermal cells: inhibition by tumor-promoting phorbol esters. Cancer Lett., 7: 71–77, 1979.
    • (1979) Cancer Lett. , vol.7 , pp. 71-77
    • Murray, A.W.1    Fusenig, N.E.2
  • 56
    • 0023664768 scopus 로고
    • Effect of phospholipid on substrate phosphorylation by a catalytic fragment of protein kinase C
    • Nakadate, T., Jeng, A. Y., and Blumberg, P. M. Effect of phospholipid on substrate phosphorylation by a catalytic fragment of protein kinase C. J. Biol. Chem., 262:11507-11513,1987.
    • (1987) J. Biol. Chem. , vol.262 , pp. 11507-11513
    • Nakadate, T.1    Jeng, A.Y.2    Blumberg, P.M.3
  • 58
    • 0022375243 scopus 로고
    • Bryostatins: potent, new mitogens that mimic phorbol ester tumor promoters
    • Smith, J. A., Smith, L., and Pettit, G. R. Bryostatins: potent, new mitogens that mimic phorbol ester tumor promoters. Biochem. Biophys. Res. Commun., 132:939-945,1985.
    • (1985) Biochem. Biophys. Res. Commun. , vol.132 , pp. 939-945
    • Smith, J.A.1    Smith, L.2    Pettit, G.R.3
  • 59
    • 0022410234 scopus 로고
    • Bryostatin, a non-phorbol macrocyclic lactone, activates intact human polymorphonuclear leukocytes and binds to the phorbol ester receptor
    • Berkow, R. L., and Kraft, A. S. Bryostatin, a non-phorbol macrocyclic lactone, activates intact human polymorphonuclear leukocytes and binds to the phorbol ester receptor. Biochem. Biophys. Res. Commun., 131:1109-1116,1985.
    • (1985) Biochem. Biophys. Res. Commun. , vol.131 , pp. 1109-1116
    • Berkow, R.L.1    Kraft, A.S.2
  • 60
    • 0010543768 scopus 로고
    • Bryostatin, an activator of the calcium phospholipid-dependent protein kinase, blocks phorbol ester-induced differentiation of human promyelocytic leukemia cells HL-60
    • Kraft, A. S., Smith, J. B., and Berkow, R. L. Bryostatin, an activator of the calcium phospholipid-dependent protein kinase, blocks phorbol ester-induced differentiation of human promyelocytic leukemia cells HL-60. Proc. Natl. Acad. Sci. USA, 83:1334-1338,1986.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 1334-1338
    • Kraft, A.S.1    Smith, J.B.2    Berkow, R.L.3
  • 61
    • 0023603491 scopus 로고
    • Inhibition by bryostatin 1 of the phorbol ester-induced blockage of differentiation in hexamethylene bisacetamide-treated Friend erythroleukemia cells
    • Dell'Aquila, M. L., Nguyen, H. T., Herald, C. L., Pettit, G. R., and Blumberg, P. M. Inhibition by bryostatin 1 of the phorbol ester-induced blockage of differentiation in hexamethylene bisacetamide-treated Friend erythroleukemia cells. Cancer Res., 47:6006-6009,1987.
    • (1987) Cancer Res. , vol.47 , pp. 6006-6009
    • Dell'Aquila, M.L.1    Nguyen, H.T.2    Herald, C.L.3    Pettit, G.R.4    Blumberg, P.M.5
  • 62
    • 0023629814 scopus 로고
    • Partial parallelism and partial blockade by bryostatin 1 of effects of phorbol ester tumor promoters on primary mouse epidermal cells
    • Sako, T., Yuspa, S. H., Herald, C. L., Pettit, G. R., and Blumberg, P. M. Partial parallelism and partial blockade by bryostatin 1 of effects of phorbol ester tumor promoters on primary mouse epidermal cells. Cancer Res., 47: 5445-5450,1987.
    • (1987) Cancer Res. , vol.47 , pp. 5445-5450
    • Sako, T.1    Yuspa, S.H.2    Herald, C.L.3    Pettit, G.R.4    Blumberg, P.M.5
  • 63
    • 0019806377 scopus 로고
    • Initiator and promoter induced specific changes in epidermal function and biological potential
    • Yuspa, S. H., Hennings, H., and Lichti, U. Initiator and promoter induced specific changes in epidermal function and biological potential. J. Cell. Biochem., 17:245-257,1981.
    • (1981) J. Cell. Biochem. , vol.17 , pp. 245-257
    • Yuspa, S.H.1    Hennings, H.2    Lichti, U.3
  • 64
    • 84965819169 scopus 로고
    • Transient inhibition of cell-cell communication in primary mouse epidermal cells by bryostatin 1
    • in press
    • Pasti, G., Rivedal, E., Yuspa, S. H., Herald, C. L., Pettit, G. R., and Blumberg, P. M. Transient inhibition of cell-cell communication in primary mouse epidermal cells by bryostatin 1. Cancer Res., in press, 1988.
    • (1988) Cancer Res
    • Pasti, G.1    Rivedal, E.2    Yuspa, S.H.3    Herald, C.L.4    Pettit, G.R.5    Blumberg, P.M.6
  • 65
    • 84965834079 scopus 로고
    • Bryostatin 1 and 9 induce phosphorylation of a unique series of 70 kDa proteins in HL-60 cells
    • Warren, B. S., Herald, C. L., Pettit, G. R., and Blumberg, P. M. Bryostatin 1 and 9 induce phosphorylation of a unique series of 70 kDa proteins in HL-60 cells. J. Cell Biochem., 11A: 47,1987.
    • (1987) J. Cell Biochem , vol.11A , pp. 47
    • Warren, B.S.1    Herald, C.L.2    Pettit, G.R.3    Blumberg, P.M.4
  • 66
    • 0023253596 scopus 로고
    • Bryostatin 1, an activator of protein kinase C, inhibits tumor promotion by phorbol esters in Sencar mouse skin
    • Hennings, H., Blumberg, P. M., Pettit, G. R., Herald, C. L., Shores, R., and Yuspa, S. H. Bryostatin 1, an activator of protein kinase C, inhibits tumor promotion by phorbol esters in Sencar mouse skin. Carcinogenesis (Lond.), 8:1312-1316 1987.
    • (1987) Carcinogenesis (Lond.) , vol.8 , pp. 1312-1316
    • Hennings, H.1    Blumberg, P.M.2    Pettit, G.R.3    Herald, C.L.4    Shores, R.5    Yuspa, S.H.6
  • 67
    • 0000370784 scopus 로고
    • Analysis of the phorbol ester pharmacophore on protein kinase C as a guide to the rational design of new classes of analogs
    • Wender, P. A., Koehler, K. F., Sharkey, N. A., Dell'Aquila, M. L., and Blumberg, P. M. Analysis of the phorbol ester pharmacophore on protein kinase C as a guide to the rational design of new classes of analogs. Proc. Natl Acad. Sci. USA, 83:4214-4218,1986.
    • (1986) Proc. Natl Acad. Sci. USA , vol.83 , pp. 4214-4218
    • Wender, P.A.1    Koehler, K.F.2    Sharkey, N.A.3    Dell'Aquila, M.L.4    Blumberg, P.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.